• 766 Citations
  • 15 h-Index
1991 …2019
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Research Output 1991 2019

  • 766 Citations
  • 15 h-Index
  • 49 Article
2019

Critical evaluation of modified-release formulation containing silybum marianum extract for oral application

Sinka, D., Hagymási, A., Fehér, P., Ujhelyi, Z., Vecsernyés, M., Fenyvesi, F., Váradi, J., Vasvári, G., Jurca, T., Nemeth, S., Popa, D. E. & Bácskay, I., jan. 1 2019, In : Farmacia. 67, 5, p. 806-819 14 p.

Research output: Article

Open Access
Milk Thistle
Silymarin
Cyclodextrins
Solubility
Biological Availability

Development and Characterisation of Gastroretentive Solid Dosage Form Based on Melt Foaming

Vasvári, G., Haimhoffer, Á., Horváth, L., Budai, I., Trencsényi, G., Béresová, M., Dobó-Nagy, C., Váradi, J., Bácskay, I., Ujhelyi, Z., Fehér, P., Sinka, D., Vecsernyés, M. & Fenyvesi, F., okt. 1 2019, In : AAPS PharmSciTech. 20, 7, 290.

Research output: Article

Open Access
Dosage Forms
Metronidazole
Stomach
Air
Technology

Fused depositionmodeling 3D printing: Test platforms for evaluating post-fabrication chemical modifications and in-vitro biological properties

Arany, P., Róka, E., Mollet, L., Coleman, A. W., Perret, F., Kim, B., Kovács, R., Kazsoki, A., Zelkó, R., Gesztelyi, R., Ujhelyi, Z., Fehér, P., Váradi, J., Fenyvesi, F., Vecsernyés, M. & Bácskay, I., jún. 2019, In : Pharmaceutics. 11, 6, 277.

Research output: Article

Open Access
Biofilms
Hydrophobic and Hydrophilic Interactions
Spectrum Analysis
Caco-2 Cells
Candida albicans

Pharmacokinetic Properties of Fluorescently Labelled Hydroxypropyl-Beta-Cyclodextrin

Váradi, J., Hermenean, A., Gesztelyi, R., Jeney, V., Balogh, E., Majoros, L., Malanga, M., Fenyvesi, É., Szente, L., Bácskay, I., Vecsernyés, M., Fehér, P., Ujhelyi, Z., Vasvári, G., Árvai, I., Rusznyák, Á., Balta, C., Herman, H. & Fenyvesi, F., szept. 20 2019, In : Biomolecules. 9, 10

Research output: Article

Open Access
Pharmacokinetics
Fluorescein-5-isothiocyanate
2-hydroxypropyl-beta-cyclodextrin
Type C Niemann-Pick Disease
Optical Imaging

Physiological and Transcriptional Responses of Candida parapsilosis to Exogenous Tyrosol

Jakab, Á., Tóth, Z., Nagy, F., Nemes, D., Bácskay, I., Kardos, G., Emri, T., Pócsi, I., Majoros, L. & Kovács, R., okt. 15 2019, In : Applied and environmental microbiology. 85, 20

Research output: Article

Candida parapsilosis
Candida
virulence
gene
genes
3 Citations (Scopus)

Radiochemical synthesis and preclinical evaluation of 68Ga-labeled NODAGA-hydroxypropyl-beta-cyclodextrin (68Ga-NODAGA-HPBCD)

Hajdu, I., Angyal, J., Szikra, D., Kertész, I., Malanga, M., Fenyvesi, É., Szente, L., Vecsernyés, M., Bácskay, I., Váradi, J., Fehér, P., Ujhelyi, Z., Vasvári, G., Rusznyák, Á., Trencsényi, G. & Fenyvesi, F., febr. 1 2019, In : European Journal of Pharmaceutical Sciences. 128, p. 202-208 7 p.

Research output: Article

Cyclodextrins
Pharmacokinetics
2-hydroxypropyl-beta-cyclodextrin
Positron-Emission Tomography
Type C Niemann-Pick Disease
1 Citation (Scopus)

Silymarin: Friend or foe of UV exposed keratinocytes?

Fidrus, E., Ujhelyi, Z., Fehér, P., Hegedus, C., Janka, E. A., Paragh, G., Vasas, G., Bácskay, I. & Remenyik, E., jan. 1 2019, In : Molecules. 24, 9, 1652.

Research output: Article

Open Access
Silymarin
Keratinocytes
cyclobutane
dosage
photosensitivity
1 Citation (Scopus)

The hepatoprotective effect of livergol microemulsion preparation (nanoparticle)against bromobenzene induced toxicity in mice

Kalantari, A., Salimi, A., Kalantari, H., Ebrahimi Broojeni, J., Rashidi, I., Raesi Vanani, A. & Bácskay, I., jan. 1 2019, In : Toxicology Reports. 6, p. 444-448 5 p.

Research output: Article

Open Access
Microemulsions
Liver
Nanoparticles
Toxicity
Milk Thistle
2018
2 Citations (Scopus)

Biocompatibility investigation of different pharmaceutical excipients used in liquid dosage forms

Nemes, D., Ujhelyi, Z., Arany, P., Peto, A., Feher, P., Váradi, J., Fenyvesi, F., Vecsernyés, M. & Bácskay, I., jan. 1 2018, In : Pharmazie. 73, 1, p. 16-18 3 p.

Research output: Article

Pharmaceutical Solutions
Benzalkonium Compounds
Polysorbates
Excipients
Social Conditions
1 Citation (Scopus)

Development and Characterisation of Modified Release Hard Gelatin Capsules, Based on In Situ Lipid Matrix Formation

Vasvári, G., Csontos, B., Sovány, T., Regdon, G., Bényei, A., Váradi, J., Bácskay, I., Ujhelyi, Z., Fehér, P., Sinka, D., Nguyen, T. L. P., Vecsernyés, M. & Fenyvesi, F., jan. 1 2018, (Accepted/In press) In : AAPS PharmSciTech.

Research output: Article

Gelatin
gelatin
Capsules
Diclofenac
Lipids
3 Citations (Scopus)

Enhancement of silymarin anti-fibrotic effects by complexation with hydroxypropyl (HPBCD) and randomly methylated (RAMEB) β-cyclodextrins in a mouse model of liver fibrosis

Gharbia, S., Balta, C., Herman, H., Rosu, M., Váradi, J., Bácskay, I., Vecsernyés, M., Gyöngyösi, S., Fenyvesi, F., Voicu, S. N., Stan, M. S., Cristian, R. E., Dinischiotu, A. & Hermenean, A., aug. 13 2018, In : Frontiers in Pharmacology. 9, AUG, 883.

Research output: Article

Silymarin
Cyclodextrins
Liver Cirrhosis
Collagen
Hepatic Stellate Cells
2 Citations (Scopus)

Interaction between different pharmaceutical excipients in liquid dosage forms—assessment of cytotoxicity and antimicrobial activity

Nemes, D., Kovács, R., Nagy, F., Mez o, M., Poczok, N., Ujhelyi, Z., Pet o, A., Fehér, P., Fenyvesi, F., Váradi, J., Vecsernyés, M. & Bácskay, I., jan. 1 2018, In : Molecules. 23, 7, 1827;.

Research output: Article

Parabens
preservatives
Excipients
biocompatibility
Cytotoxicity
6 Citations (Scopus)

Matrix systems for oral drug delivery: Formulations and drug release

Vasvári, G., Kalmár, J., Veres, P., Vecsernyés, M., Bácskay, I., Fehér, P., Ujhelyi, Z., Haimhoffer, Á., Rusznyák, Á., Fenyvesi, F. & Váradi, J., jan. 1 2018, (Accepted/In press) In : Drug Discovery Today: Technologies.

Research output: Article

Drug Compounding
Excipients
Pharmaceutical Technology
Dosage Forms
Pharmaceutical Preparations

Physico-chemical characterization of self-emulsifying drug delivery systems

Ujhelyi, Z., Vecsernyés, M., Fehér, P., Kósa, D., Arany, P., Nemes, D., Sinka, D., Vasvári, G., Fenyvesi, F., Váradi, J. & Bácskay, I., jan. 1 2018, (Accepted/In press) In : Drug Discovery Today: Technologies.

Research output: Article

Drug Delivery Systems
Fourier Transform Infrared Spectroscopy
Photons
Viscosity
Biological Availability
7 Citations (Scopus)

Protective effect of pure sour cherry anthocyanin extract on cytokine-induced inflammatory caco-2 monolayers

Nguyen, T. L. P., Fenyvesi, F., Remenyik, J., Homoki, J. R., Gogolák, P., Bácskay, I., Fehér, P., Ujhelyi, Z., Vasvári, G., Vecsernyés, M. & Váradi, J., júl. 3 2018, In : Nutrients. 10, 7, 861.

Research output: Article

Prunus cerasus
Anthocyanins
protective effect
anthocyanins
cytokines
2017
3 Citations (Scopus)

Self-nanoemulsifying drug delivery systems containing plantago lanceolata—an assessment of their antioxidant and antiinflammatory effects

Kalantari, A., Kósa, D., Nemes, D., Ujhelyi, Z., Fehér, P., Vecsernyés, M., Váradi, J., Fenyvesi, F., Kuki, Á., Gonda, S., Vasas, G., Gesztelyi, R., Salimi, A. & Bácskay, I., okt. 1 2017, In : Molecules. 22, 10, 1773.

Research output: Article

Plantago
antioxidants
Drug Delivery Systems
delivery
drugs
2016
14 Citations (Scopus)
Milk Thistle
guinea pigs
Oxidative stress
Keratinocytes
pretreatment
2015
7 Citations (Scopus)

Antioxidant and hepatoprotective activity of milk thistle (Silybum marianum L. Gaertn.) seed oil

Hermenean, A., Stan, M., Ardelean, A., Pilat, L., Mihali, C. V., Popescu, C., Nagy, L., Deák, G., Zsuga, M., Kéki, S., Bácskay, I., Fenyvesi, F., Costache, M., Dinischiotu, A. & Vecsernyés, M., jan. 1 2015, In : Open Life Sciences. 10, 1, p. 147-158 12 p.

Research output: Article

Milk Thistle
Silybum marianum
Oilseeds
hepatoprotective effect
seed oils
24 Citations (Scopus)

Endocytosis of fluorescent cyclodextrins by intestinal Caco-2 cells and its role in paclitaxel drug delivery

Réti-Nagy, K., Malanga, M., Fenyvesi, É., Szente, L., Vámosi, G., Váradi, J., Bácskay, I., Fehér, P., Ujhelyi, Z., Róka, E., Vecsernyés, M., Balogh, G., Vasvári, G. & Fenyvesi, F., dec. 30 2015, In : International Journal of Pharmaceutics. 496, 2, p. 509-517 9 p.

Research output: Article

Caco-2 Cells
Cyclodextrins
Endocytosis
Paclitaxel
Pharmaceutical Preparations
22 Citations (Scopus)

Evaluation of the cytotoxicity of α-cyclodextrin derivatives on the caco-2 cell line and human erythrocytes

Róka, E., Ujhelyi, Z., Deli, M., Bocsik, A., Fenyvesi, É., Szente, L., Fenyvesi, F., Vecsernyés, M., Váradi, J., Fehér, P., Gesztelyi, R., Félix, C., Perret, F. & Bácskay, I., nov. 11 2015, In : Molecules. 20, 11, p. 20269-20285 17 p.

Research output: Article

Caco-2 Cells
Cyclodextrins
erythrocytes
Cytotoxicity
cultured cells
8 Citations (Scopus)

Hepatoprotective effects of a self-micro emulsifying drug delivery system containing Silybum marianum native seed oil against experimentally induced liver injury

Fehér, P., Ujhelyi, Z., Vecsernyés, M., Fenyvesi, F., Damache, G., Ardelean, A., Costache, M., Dinischiotu, A., Hermenean, A. & Bácskay, I., ápr. 1 2015, In : Pharmazie. 70, 4, p. 231-238 8 p.

Research output: Article

Milk Thistle
Drug Delivery Systems
Seeds
Oils
Silymarin
6 Citations (Scopus)

para-sulphonato-calix[n]arenes as selective activators for the passage of molecules across the Caco-2 model intestinal membrane

Roka, E., Vecsernyés, M., Bácskay, I., Félix, C., Rhimi, M., Coleman, A. W. & Perret, F., jún. 7 2015, In : Chemical Communications. 51, 45, p. 9374-9376 3 p.

Research output: Article

Calixarenes
Membranes
Molecules
lucifer yellow
11 Citations (Scopus)

The enhanced inhibitory effect of different antitumor agents in self-microemulsifying drug delivery systems on human cervical cancer HeLa cells

Ujhelyi, Z., Kalantari, A., Vecsernyés, M., Róka, E., Fenyvesi, F., Póka, R., Kozma, B. & Bácskay, I., júl. 1 2015, In : Molecules. 20, 7, p. 13226-13239 14 p.

Research output: Article

Drug Delivery Systems
HeLa Cells
Uterine Cervical Neoplasms
Antineoplastic Agents
delivery
2014
41 Citations (Scopus)

Cyclodextrins, Blood-Brain Barrier, and Treatment of Neurological Diseases

Vecsernyés, M., Fenyvesi, F., Bácskay, I., Deli, M., Szente, L. & Fenyvesi, É., nov. 1 2014, In : Archives of Medical Research. 45, 8, p. 711-729 19 p.

Research output: Article

Cyclodextrins
Blood-Brain Barrier
Pharmaceutical Preparations
Excipients
Therapeutics
29 Citations (Scopus)

Fluorescently labeled methyl-beta-cyclodextrin enters intestinal epithelial Caco-2 cells by fluid-phase endocytosis

Fenyvesi, F., Réti-Nagy, K., Bacsó, Z., Gutay-Tóth, Z., Malanga, M., Fenyvesi, É., Szente, L., Váradi, J., Ujhelyi, Z., Fehér, P., Szabó, G., Vecsernyés, M. & Bácskay, I., jan. 8 2014, In : PLoS One. 9, 1, e84856.

Research output: Article

Caco-2 Cells
Fluorescein-5-isothiocyanate
beta-cyclodextrin
endocytosis
Endocytosis
10 Citations (Scopus)

Investigation of the cytotoxic effects of titanate nanotubes on Caco-2 cells

Fenyvesi, F., Kónya, Z., Rázga, Z., Vecsernyés, M., Kása, P., Pintye-Hódi, K. & Bácskay, I., 2014, In : AAPS PharmSciTech. 15, 4, p. 858-861 4 p.

Research output: Article

nanotubes
Nanotubes
Caco-2 Cells
cytotoxicity
Drug Delivery Systems
1 Citation (Scopus)
Drug Delivery Systems
Surface-Active Agents
Caco-2 Cells
HeLa Cells
Poisons
2013
5 Citations (Scopus)

Assessment of the hemolytic activity and cytotoxicity of different PEG-based solubilizing agents

Ujhelyi, Z., Róka, E., Fenyvesi, F., Fehér, P., Váradi, J., Réti-Nagy, K., Vecsernyés, M. & Bácskay, I., máj. 2013, In : Pharmazie. 68, 5, p. 383-384 2 p.

Research output: Article

Surface-Active Agents
In Vitro Techniques
thiazolyl blue
2012
83 Citations (Scopus)
Caco-2 Cells
Drug Delivery Systems
Surface-Active Agents
Polysorbates
Esters
2011
31 Citations (Scopus)
Caco-2 Cells
Cyclodextrins
Paclitaxel
Permeability
Epithelial Cells
2010
12 Citations (Scopus)
Median Eminence
Tyrosine 3-Monooxygenase
Prolactin
Hypothalamus
Hormones
105 Citations (Scopus)

Evaluation of the cytotoxicity of β-cyclodextrin derivatives: Evidence for the role of cholesterol extraction

Kiss, T., Fenyvesi, F., Bácskay, I., Váradi, J., Fenyvesi, É., Iványi, R., Szente, L., Tósaki, A. & Vecsernyés, M., júl. 2010, In : European Journal of Pharmaceutical Sciences. 40, 4, p. 376-380 5 p.

Research output: Article

Cyclodextrins
Cholesterol
Caco-2 Cells
Poisons
Cell Survival
2009
12 Citations (Scopus)

Dopamine-regulated adrenocorticotropic hormone secretion in lactating rats: Functional plasticity of melanotropes

Oláh, M., Fehér, P., Ihm, Z., Bácskay, I., Kiss, T., Freeman, M. E., Nagy, G. M. & Vecsernyés, M., nov. 2009, In : Neuroendocrinology. 90, 4, p. 391-401 11 p.

Research output: Article

Adrenocorticotropic Hormone
Dopamine
Melanocyte-Stimulating Hormones
Intermediate Pituitary Gland
Domperidone
2008
55 Citations (Scopus)

P-glycoprotein inhibition by membrane cholesterol modulation

Fenyvesi, F., Fenyvesi, É., Szente, L., Goda, K., Bacsó, Z., Bácskay, I., Váradi, J., Kiss, T., Molnár, É., Janáky, T., Szabó, G. & Vecsernyés, M., aug. 7 2008, In : European Journal of Pharmaceutical Sciences. 34, 4-5, p. 236-242 7 p.

Research output: Article

P-Glycoprotein
Cholesterol
Membranes
Cyclodextrins
Adenosine Triphosphate
2007
39 Citations (Scopus)

Beneficial effects of carbon monoxide-releasing molecules on post-ischemic myocardial recovery

Váradi, J., Lekli, I., Juhász, B., Bácskay, I., Szabo, G., Gesztelyi, R., Szendrei, L., Varga, E., Bak, I., Foresti, R., Motterlini, R. & Tósaki, A., ápr. 3 2007, In : Life Sciences. 80, 17, p. 1619-1626 8 p.

Research output: Article

Carbon Monoxide
Recovery
Molecules
Ventricular Fibrillation
Incidence
20 Citations (Scopus)

Cytotoxicity of different types of methylated β-cyclodextrins and ionic derivatives

Kiss, T., Fenyvesi, F., Pasztor, N., Feher, P., Váradi, J., Kocsan, R., Szente, L., Fenyvesi, E., Szabo, G., Vecsernyés, M. & Bácskay, I., júl. 2007, In : Pharmazie. 62, 7, p. 557-558 2 p.

Research output: Article

Cyclodextrins
Cytotoxicity
Derivatives
Substitution reactions
Poisons
2006
54 Citations (Scopus)
Reperfusion Injury
Reperfusion
Seeds
Ischemia
Ventricular Fibrillation
31 Citations (Scopus)

Synthesis and cytotoxicity of leinamycin antibiotic analogues

Szilágyi, Á., Fenyvesi, F., Majercsik, O., Pelyvás, I. F., Bácskay, I., Fehér, P., Váradi, J., Vecsernyés, M. & Herczegh, P., szept. 7 2006, In : Journal of Medicinal Chemistry. 49, 18, p. 5626-5630 5 p.

Research output: Article

Cytotoxicity
Anti-Bacterial Agents
Carbon
Derivatives
Arabinose
2005
1 Citation (Scopus)

Cytotoxicity of different types of surfactants on HeLa cells

Bácskay, I., Kocsán, R., Fenyvesi, F., Fehér, P., Sipos, T., Váradi, J. & Vecsernyés, M., máj. 2005, In : European Journal of Pharmaceutical Sciences. 25, SUPPL. 1

Research output: Article

HeLa Cells
Surface-Active Agents
2004
26 Citations (Scopus)
Reperfusion
Myocardium
Hypercholesterolemia
Cardiac Arrhythmias
Animal Diseases
2003
51 Citations (Scopus)

Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium.

Bak, I., Szendrei, L., Turoczi, T., Papp, G., Joo, F., Das, D. K., de Leiris, J., Der, P., Juhász, B., Varga, E., Bácskay, I., Balla, J., Kovacs, P. & Tósaki, A., 2003, In : FASEB Journal. 17, 14, p. 2133-2135 3 p.

Research output: Article

Heme Oxygenase-1
Ventricular Fibrillation
Carbon Monoxide
Myocardium
Enzyme activity
25 Citations (Scopus)
Melanocyte-Stimulating Hormones
Reperfusion
Myocardium
Ventricular Fibrillation
Ventricular Pressure
2001
1 Citation (Scopus)
Photometry
Suppositories
Diazepam
Lasers
Status Epilepticus
1995
3 Citations (Scopus)
Cyclodextrins
Diazepam
Suppositories
Pharmaceutical Preparations
Solubility
1994
5 Citations (Scopus)

Formulation of diazepam containing rectal suppositories and experiences of their biopharmaceutical study

Regdon, G., Bacskay, I., Kata, M., Selmeczi, B., Szikszay, M., Santa, A. & Balint, G. S., 1994, In : Pharmazie. 49, 5, p. 346-349 4 p.

Research output: Article

Suppositories
Molecular mass
Diazepam
Membranes
Biological Availability
1993
2 Citations (Scopus)

Formulation of diazepam suppositories, results of the rheological and biopharmaceutical studies. 2. In vitro membrane diffusion and in vivo absorption results

Bácskay, I., Regdon, G., Kata, M., Selmeczi, B., Szikszay, M., Santa, A. & Balint, G. S., 1993, In : Acta Pharmaceutica Hungarica. 63, 5, p. 277-283 7 p.

Research output: Article

Suppositories
Diazepam
Membranes
Biological Availability
Publications
1 Citation (Scopus)
Suppositories
Diazepam
Viscosity
Plastics
1991
2 Citations (Scopus)

Production and in vitro examination of suppositoria of diazepam content

Regdon, G., Bácskay, I., Kata, M. & Regdon, G., 1991, In : Gyogyszereszet. 35, 5, p. 219-222 4 p.

Research output: Article

Diazepam
In Vitro Techniques