• 4990 Citations
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19972020

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Article
2020

A novel deep intronic SERPING1 variant as a cause of hereditary angioedema due to C1-inhibitor deficiency

Vatsiou, S., Zamanakou, M., Loules, G., Psarros, F., Parsopoulou, F., Csuka, D., Valerieva, A., Staevska, M., Porebski, G., Obtulowicz, K., Magerl, M., Maurer, M., Speletas, M., Farkas, H. & Germenis, A. E., jan. 1 2020, (Accepted/In press) In : Allergology International.

Research output: Article

Open Access

Changes of coagulation parameters during erythema marginatum in patients with hereditary angioedema

Kőhalmi, K. V., Mező, B., Veszeli, N., Benedek, S., Fehér, A., Holdonner, Á., Jesenak, M., Varga, L. & Farkas, H., ápr. 2020, In : International Immunopharmacology. 81, 106293.

Research output: Article

Open Access
1 Citation (Scopus)

Evaluation of the efficacy and safety of home treatment with the recombinant human C1-inhibitor in hereditary angioedema resulting from C1-inhibitor deficiency

Andrási, N., Veszeli, N., Holdonner, Á., Temesszentandrási, G., Kőhalmi, K. V., Varga, L. & Farkas, H., márc. 2020, In : International Immunopharmacology. 80, 106216.

Research output: Article

Open Access

Hereditary angioedema attack: what happens to vasoactive mediators?

Ferrara, A. L., Bova, M., Petraroli, A., Veszeli, N., Galdiero, M. R., Braile, M., Marone, G., Cristinziano, L., Marcella, S., Modestino, L., Farkas, H. & Loffredo, S., jan. 2020, In : International Immunopharmacology. 78, 106079.

Research output: Article

Open Access
1 Citation (Scopus)
Open Access

Long-term efficacy and safety of subcutaneous C1-inhibitor in women with hereditary angioedema: Subgroup analysis from an open-label extension of a phase 3 trial

Levy, D. S., Farkas, H., Riedl, M. A., Hsu, F. I., Brooks, J. P., Cicardi, M., Feuersenger, H., Pragst, I. & Reshef, A., febr. 4 2020, In : Allergy, Asthma and Clinical Immunology. 16, 1, 8.

Research output: Article

Open Access

Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients

Kajdácsi, E., Jandrasics, Z., Veszeli, N., Makó, V., Koncz, A., Gulyás, D., Köhalmi, K. V., Temesszentandrási, G., Cervenak, L., Gál, P., Dobó, J., de Maat, S., Maas, C., Farkas, H. & Varga, L., máj. 5 2020, In : Frontiers in immunology. 11, 794.

Research output: Article

Open Access
2019

Flow-mediated vasodilation assay indicates no endothelial dysfunction in hereditary angioedema patients with C1-inhibitor deficiency

Nebenführer, Z., Szabó, E., Kajdácsi, E., Kőhalmi, K. V., Karádi, I., Zsáry, A., Farkas, H. & Cervenák, L., jan. 1 2019, In : Annals of Allergy, Asthma and Immunology. 122, 1, p. 86-92 7 p.

Research output: Article

2 Citations (Scopus)

Recombinant human C1 esterase inhibitor treatment for hereditary angioedema attacks in children

Reshef, A., Grivcheva-Panovska, V., Kessel, A., Kivity, S., Klimaszewska-Rembiasz, M., Moldovan, D., Farkas, H., Gutova, V., Fritz, S., Relan, A., Giannetti, B. & Magerl, M., aug. 2019, In : Pediatric Allergy and Immunology. 30, 5, p. 562-568 7 p.

Research output: Article

Open Access
3 Citations (Scopus)
Open Access
2018

Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation

Cao, H., Biondo, M., Lioe, H., Busfield, S., Rayzman, V., Nieswandt, B., Bork, K., Harrison, L. C., Auyeung, P., Farkas, H., Csuka, D., Pelzing, M., Dower, S., Wilson, M. J., Nash, A., Nolte, M. W. & Panousis, C., jan. 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Article

5 Citations (Scopus)

Complete kinetic follow-up of symptoms and complement parameters during a hereditary angioedema attack

Veszeli, N., Kőhalmi, K. V., Kajdácsi, E., Gulyás, D., Temesszentandrási, G., Cervenak, L., Farkas, H. & Varga, L., febr. 1 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 2, p. 516-520 5 p.

Research output: Article

4 Citations (Scopus)

Diagnostyka wrodzonego obrzȩku naczynioruchowego

Koőhalmi, K. V., Cervenák, L. & Farkas, H., dec. 1 2018, In : Alergia Astma Immunologia. 23, 4, p. 168-174 7 p.

Research output: Article

Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema

Lumry, W. R., Craig, T., Zuraw, B., Longhurst, H., Baker, J., Li, H. H., Bernstein, J. A., Anderson, J., Riedl, M. A., Manning, M. E., Keith, P. K., Levy, D. S., Caballero, T., Banerji, A., Gower, R. G., Farkas, H., Lawo, J. P., Pragst, I., Machnig, T. & Watson, D. J., szept. 1 2018, In : Journal of Allergy and Clinical Immunology: In Practice. 6, 5, p. 1733-1741.e3

Research output: Article

16 Citations (Scopus)
6 Citations (Scopus)

Idiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema

Andrási, N., Veszeli, N., Kőhalmi, K. V., Csuka, D., Temesszentandrási, G., Varga, L. & Farkas, H., júl. 1 2018, In : Journal of Allergy and Clinical Immunology: In Practice. 6, 4, p. 1205-1208 4 p.

Research output: Article

3 Citations (Scopus)

Lanadelumab for the Prophylactic Treatment of Hereditary Angioedema with C1 Inhibitor Deficiency: A Review of Preclinical and Phase I Studies

Busse, P. J., Farkas, H., Banerji, A., Lumry, W. R., Longhurst, H. J., Sexton, D. J. & Riedl, M. A., jan. 1 2018, (Accepted/In press) In : BioDrugs.

Research output: Article

5 Citations (Scopus)

Secreted phospholipases A2 in hereditary angioedema with C1-inhibitor deficiency

Loffredo, S., Ferrara, A. L., Bova, M., Borriello, F., Suffritti, C., Veszeli, N., Petraroli, A., Galdiero, M. R., Varricchi, G., Granata, F., Zanichelli, A., Farkas, H., Cicardi, M., Lambeau, G. & Marone, G., júl. 23 2018, In : Frontiers in immunology. 9, JUL, 1721.

Research output: Article

8 Citations (Scopus)

Targeted next-generation sequencing for the molecular diagnosis of hereditary angioedema due to C1-inhibitor deficiency

Loules, G., Zamanakou, M., Parsopoulou, F., Vatsiou, S., Psarros, F., Csuka, D., Porebski, G., Obtulowicz, K., Valerieva, A., Staevska, M., López-Lera, A., López-Trascasa, M., Moldovan, D., Magerl, M., Maurer, M., Speletas, M., Farkas, H. & Germenis, A. E., aug. 15 2018, In : Gene. 667, p. 76-82 7 p.

Research output: Article

13 Citations (Scopus)

Wybrane aspekty genotypowania wrodzonego obrzȩku naczynioruchowego w erze NGS: Gen F12

Vatsiou, S., Zamanakou, M., Loules, G., González-Quevedo, T., Porȩbski, G., Juchacz, A., Bova, M., Suffritti, C., Firinu, D., Csuka, D., Manousakis, E., Valerieva, A., Staevska, M., Magerl, M., Farkas, H. & Germenis, A. E., dec. 2018, In : Alergia Astma Immunologia. 23, 4, p. 205-210 6 p.

Research output: Article

2017
4 Citations (Scopus)

Cleaved kininogen as a biomarker for bradykinin release in hereditary angioedema

Hofman, Z. L. M., de Maat, S., van Doorn, C., Sebastian, S. A. E., Pasterkamp, G., Maas, C., Hofman, Z. L. M., Hack, C. E., Suffritti, C., Zanichelli, A., Cicardi, M., Veszeli, N., Csuka, D., Farkas, H., Renné, T. & Renné, T., dec. 1 2017, In : Journal of Allergy and Clinical Immunology. 140, 6, p. 1700-1703.e8

Research output: Article

17 Citations (Scopus)

Genetic determinants of C1 inhibitor deficiency angioedema age of onset

Gianni, P., Loules, G., Zamanakou, M., Kompoti, M., Csuka, D., Psarros, F., Magerl, M., Moldovan, D., Maurer, M., Speletas, M. G., Farkas, H. & Germenis, A. E., jan. 1 2017, In : International archives of allergy and immunology. 174, 3-4, p. 200-204 5 p.

Research output: Article

9 Citations (Scopus)

Glucocorticoid receptor gene polymorphisms in hereditary angioedema with C1-inhibitor deficiency

Zotter, Z., Nagy, Z., Patócs, A., Csuka, D., Veszeli, N., Kohalmi, K. V. & Farkas, H., jan. 10 2017, In : Orphanet journal of rare diseases. 12, 1, 5.

Research output: Article

2 Citations (Scopus)

Health-related quality of life among children with hereditary angioedema

Engel-Yeger, B., Farkas, H., Kivity, S., Veszeli, N., Kőhalmi, K. V. & Kessel, A., jún. 1 2017, In : Pediatric Allergy and Immunology. 28, 4, p. 370-376 7 p.

Research output: Article

18 Citations (Scopus)
60 Citations (Scopus)

The relationship between anxiety and quality of life in children with hereditary angioedema

Kessel, A., Farkas, H., Kivity, S., Veszeli, N., Kőhalmi, K. V. & Engel-Yeger, B., nov. 1 2017, In : Pediatric Allergy and Immunology. 28, 7, p. 692-698 7 p.

Research output: Article

10 Citations (Scopus)

Treatment Effect and Safety of Icatibant in Pediatric Patients with Hereditary Angioedema

Farkas, H., Reshef, A., Aberer, W., Caballero, T., McCarthy, L., Hao, J., Nothaft, W., Schranz, J., Bernstein, J. A. & Li, H. H., nov. 2017, In : Journal of Allergy and Clinical Immunology: In Practice. 5, 6, p. 1671-1678.e2

Research output: Article

20 Citations (Scopus)
2016

Assessment of inhibitory antibodies in patients with hereditary angioedema treated with plasma-derived C1 inhibitor

Farkas, H., Varga, L., Moldovan, D., Obtulowicz, K., Shirov, T., Machnig, T., Feuersenger, H., Edelman, J., Williams-Herman, D. & Rojavin, M., nov. 1 2016, In : Annals of Allergy, Asthma and Immunology. 117, 5, p. 508-513 6 p.

Research output: Article

5 Citations (Scopus)
2 Citations (Scopus)

Bacteriuria increases the risk of edematous attacks in hereditary angioedema with C1-inhibitor deficiency

Zotter, Z., Veszeli, N., Kőhalmi, K. V., Varga, L., Imreh, Kovács, G., Nallbani, M. & Farkas, H., dec. 1 2016, In : Allergy: European Journal of Allergy and Clinical Immunology. 71, 12, p. 1791-1793 3 p.

Research output: Article

3 Citations (Scopus)

Erythema marginatum as an early symptom of hereditary angioedema: Case report of 2 newborns

Martinez-Saguer, I. & Farkas, H., febr. 1 2016, In : Pediatrics. 137, 2, e20152411.

Research output: Article

15 Citations (Scopus)

First report of icatibant treatment in a pregnant patient with hereditary angioedema

Farkas, H., Kőhalmi, K. V., Veszeli, N., Tóth, F. & Varga, L., aug. 1 2016, In : Journal of Obstetrics and Gynaecology Research. 42, 8, p. 1026-1028 3 p.

Research output: Article

9 Citations (Scopus)

Icatibant as acute treatment for hereditary angioedema in adults

Farkas, H., máj. 14 2016, (Accepted/In press) In : Expert Review of Clinical Pharmacology. p. 1-10 10 p.

Research output: Article

7 Citations (Scopus)
10 Citations (Scopus)

Psychometric Field Study of Hereditary Angioedema Quality of Life Questionnaire for Adults: HAE-QoL

Prior, N., Remor, E., Pérez-Fernández, E., Caminoa, M., Gómez-Traseira, C., Gayá, F., Aabom, A., Aberer, W., Betschel, S., Boccon-Gibod, I., Bouillet, L., Bygum, A., Csuka, D., Farkas, H., Gomide, M., Grumach, A., Leibovich, I., Malbran, A., Moldovan, D., Mihaly, E. & 9 others, Obtulowicz, K., Perpén, C., Peveling-Oberhag, A., Porebski, G., Chavannes, C. R., Reshef, A., Staubach, P., Wiednig, M. & Caballero, T., máj. 1 2016, In : Journal of Allergy and Clinical Immunology: In Practice. 4, 3, p. 464-473.e4

Research output: Article

19 Citations (Scopus)

Risk of thromboembolism in patients with hereditary angioedema treated with plasma-derived C1-inhibitor

Farkas, H., Kohalmi, K. V., Veszeli, N., Zotter, Z., Várnai, K. & Varga, L., márc. 1 2016, In : Allergy and Asthma Proceedings. 37, 2, p. 164-170 7 p.

Research output: Article

13 Citations (Scopus)

The effect of long-term danazol treatment on haematological parameters in hereditary angioedema Rare immune deficiencies

Kohalmi, K. V., Veszeli, N., Zotter, Z., Csuka, D., Benedek, S., Imreh, É., Varga, L. & Farkas, H., febr. 25 2016, In : Orphanet journal of rare diseases. 11, 1, 18.

Research output: Article

6 Citations (Scopus)

Thromboembolierisiko bei hereditärem Angioödem unter Therapie mit plasmatischem C1-Esterase-Inhibitor

Farkas, H., Köhalmi, K. V., Veszeli, N., Zotter, Z., Värnai, K. & Varga, L., márc. 1 2016, In : Vasomed. 28, 2, p. 72-73 2 p.

Research output: Article

Thyroid hormones and complement parameters in hereditary angioedema with C1-inhibitor deficiency

Czaller, I., Csuka, D., Zotter, Z., Veszeli, N., Takács, E., Imreh, É., Varga, L. & Farkas, H., aug. 1 2016, In : Annals of Allergy, Asthma and Immunology. 117, 2, p. 175-179 5 p.

Research output: Article

1 Citation (Scopus)
2015

A novel assay to diagnose hereditary angioedema utilizing inhibition of bradykinin-forming enzymes

Joseph, K., Bains, S., Tholanikunnel, B. G., Bygum, A., Aabom, A., Koch, C., Farkas, H., Varga, L., Ghebrehiwet, B. & Kaplan, A. P., jan. 1 2015, In : Allergy: European Journal of Allergy and Clinical Immunology. 70, 1, p. 115-119 5 p.

Research output: Article

14 Citations (Scopus)
23 Citations (Scopus)

F12-46C/T polymorphism as modifier of the clinical phenotype of hereditary angioedema

Speletas, M., Szilágyi, Csuka, D., Koutsostathis, N., Psarros, F., Moldovan, D., Magerl, M., Kompoti, M., Varga, L., Maurer, M., Farkas, H. & Germenis, A. E., dec. 1 2015, In : Allergy: European Journal of Allergy and Clinical Immunology. 70, 12, p. 1661-1664 4 p.

Research output: Article

19 Citations (Scopus)

Hereditary angioedema: Molecular and clinical differences among European populations

Speletas, M., Szilagyi, A., Psarros, F., Moldovan, D., Magerl, M., Kompoti, M., Gramoustianou, E., Bors, A., Mihaly, E., Tordai, A., Avramouli, A., Varga, L., Maurer, M., Farkas, H. & Germenis, A. E., febr. 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 2, p. 570-573.e10

Research output: Article

35 Citations (Scopus)

Icatibant for Multiple Hereditary Angioedema Attacks across the Controlled and Open-Label Extension Phases of FAST-3

Lumry, W. R., Farkas, H., Moldovan, D., Toubi, E., Baptista, J., Craig, T. & Riedl, M., dec. 1 2015, In : International archives of allergy and immunology. 168, 1, p. 44-55 12 p.

Research output: Article

12 Citations (Scopus)

Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency

Veszeli, N., Csuka, D., Zotter, Z., Imreh, É., Józsi, M., Benedek, S., Varga, L. & Farkas, H., dec. 10 2015, In : Orphanet journal of rare diseases. 10, 1, 374.

Research output: Article

14 Citations (Scopus)

Successful prophylaxis with recombinant human C1 inhibitor in a patient with hereditary angioedema

Farkas, H., Kohalmi, K. V., Veszeli, N., Zotter, Z. & Varga, L., jan. 1 2015, In : Annals of Allergy, Asthma and Immunology. 114, 1, p. 64-65 2 p.

Research output: Article

5 Citations (Scopus)