• 4221 Citations
  • 35 h-Index
1981 …2020
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Research Output 1981 2020

  • 4221 Citations
  • 35 h-Index
  • 209 Article
  • 10 Conference contribution
  • 5 Chapter
  • 2 Review article
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Article
2020

Continuous drying of a protein-type drug using scaled-up fiber formation with HP-β-CD matrix resulting in a directly compressible powder for tableting

Vass, P., Nagy, Z. K., Kóczián, R., Fehér, C., Démuth, B., Szabó, E., Andersen, S. K., Vigh, T., Verreck, G., Csontos, I., Marosi, G. & Hirsch, E., jan. 1 2020, In : European Journal of Pharmaceutical Sciences. 141, 105089.

Research output: Article

Powders
Cyclodextrins
Pharmaceutical Preparations
Tablets
Proteins
2019

3D floating tablets: Appropriate 3D design from the perspective of different in vitro dissolution testing methodologies

Ilyés, K., Balogh, A., Casian, T., Igricz, T., Borbás, E., Démuth, B., Vass, P., Menyhárt, L., Kovács, N. K., Marosi, G., Tomuță, I. & Nagy, Z. K., aug. 15 2019, In : International Journal of Pharmaceutics. 567, 118433.

Research output: Article

Tablets
In Vitro Techniques

Application of artificial neural networks for Process Analytical Technology-based dissolution testing

Nagy, B., Petra, D., Galata, D. L., Démuth, B., Borbás, E., Marosi, G., Nagy, Z. K. & Farkas, A., aug. 15 2019, In : International Journal of Pharmaceutics. 567, 118464.

Research output: Article

Tablets
Technology
Neural Networks (Computer)
Least-Squares Analysis
Pharmaceutical Preparations
9 Citations (Scopus)

Continuous alternative to freeze drying: Manufacturing of cyclodextrin-based reconstitution powder from aqueous solution using scaled-up electrospinning

Vass, P., Démuth, B., Farkas, A., Hirsch, E., Szabó, E., Nagy, B., Andersen, S. K., Vigh, T., Verreck, G., Csontos, I., Marosi, G. & Nagy, Z. K., márc. 28 2019, In : Journal of Controlled Release. 298, p. 120-127 8 p.

Research output: Article

Freeze Drying
Cyclodextrins
Powders
Cyclonic Storms
Excipients
2 Citations (Scopus)

Continuous manufacturing of orally dissolving webs containing a poorly soluble drug via electrospinning

Domokos, A., Balogh, A., Dénes, D., Nyerges, G., Ződi, L., Farkas, B., Marosi, G. & Nagy, Z. K., márc. 15 2019, In : European Journal of Pharmaceutical Sciences. 130, p. 91-99 9 p.

Research output: Article

Nanofibers
Citric Acid
Pharmaceutical Preparations
Solubility
Mouth
3 Citations (Scopus)

Corona alternating current electrospinning: A combined approach for increasing the productivity of electrospinning

Farkas, B., Balogh, A., Cselkó, R., Molnár, K., Farkas, A., Borbás, E., Marosi, G. & Nagy, Z. K., ápr. 20 2019, In : International Journal of Pharmaceutics. 561, p. 219-227 9 p.

Research output: Article

Spironolactone
Povidone
Sodium Dodecyl Sulfate
Needles
Water

Data fusion strategies for performance improvement of a Process Analytical Technology platform consisting of four instruments: An electrospinning case study

Casian, T., Farkas, A., Ilyés, K., Démuth, B., Borbás, E., Madarász, L., Rapi, Z., Farkas, B., Balogh, A., Domokos, A., Marosi, G., Tomută, I. & Nagy, Z. K., aug. 15 2019, In : International Journal of Pharmaceutics. 567, 118473.

Research output: Article

meloxicam
Data Compression
Colorimetry
Near-Infrared Spectroscopy
Raman Spectrum Analysis

Development of bioepoxy resin microencapsulated ammonium-polyphosphate for flame retardancy of polylactic acid

Decsov, K., Bocz, K., Szolnoki, B., Bourbigot, S., Fontaine, G., Vadas, D. & Marosi, G., nov. 14 2019, In : Molecules. 24, 22, 4123.

Research output: Article

Open Access
Polyphosphates
Ammonium Compounds
resins
flames
flame retardants
Flame Retardants
Flammability
Sugars
Phosphorus
Polyphosphates

Electrospun amorphous solid dispersions of meloxicam: Influence of polymer type and downstream processing to orodispersible dosage forms

Casian, T., Borbás, E., Ilyés, K., Démuth, B., Farkas, A., Rapi, Z., Bogdan, C., Iurian, S., Toma, V., Știufiuc, R., Farkas, B., Balogh, A., Marosi, G., Tomuță, I. & Nagy, Z. K., okt. 5 2019, In : International Journal of Pharmaceutics. 569, 118593.

Research output: Article

meloxicam
Dosage Forms
Polymers
Tablets
Tensile Strength

Fast, spectroscopy-based prediction of in vitro dissolution profile of extended release tablets using artificial neural networks

Galata, D. L., Farkas, A., Könyves, Z., Mészáros, L. A., Szabó, E., Csontos, I., Pálos, A., Marosi, G., Nagy, Z. K. & Nagy, B., aug. 1 2019, In : Pharmaceutics. 11, 8, 400.

Research output: Article

Open Access
Neural Networks (Computer)
Tablets
Spectrum Analysis
Near-Infrared Spectroscopy
Raman Spectrum Analysis
1 Citation (Scopus)

Inline noninvasive Raman monitoring and feedback control of glucose concentration during ethanol fermentation

Hirsch, E., Pataki, H., Domján, J., Farkas, A., Vass, P., Fehér, C., Barta, Z., Nagy, Z. K., Marosi, G. & Csontos, I., jan. 1 2019, In : Biotechnology Progress. e2848.

Research output: Article

Open Access
Fermentation
Ethanol
Glucose
Raman Spectrum Analysis
Yeasts

Scaled-Up production and tableting of grindable electrospun fibers containing a protein-type drug

Vass, P., Hirsch, E., Kóczián, R., Démuth, B., Farkas, A., Fehér, C., Szabó, E., Németh, Á., Andersen, S. K., Vigh, T., Verreck, G., Csontos, I., Marosi, G. & Nagy, Z. K., júl. 1 2019, In : Pharmaceutics. 11, 7, 329.

Research output: Article

Open Access
Galactosidases
Tablets
Mannitol
Polyvinyl Alcohol
Pharmaceutical Preparations
3 Citations (Scopus)
Pharmaceutical Preparations
Excipients
Dosage Forms
Product Packaging
Humidity
2018
4 Citations (Scopus)

Application of hydroxypropyl methylcellulose as a protective agent against magnesium stearate induced crystallization of amorphous itraconazole

Démuth, B., Galata, D. L., Balogh, A., Szabó, E., Nagy, B., Farkas, A., Hirsch, E., Pataki, H., Vigh, T., Mensch, J., Verreck, G., Nagy, Z. K. & Marosi, G., aug. 30 2018, In : European Journal of Pharmaceutical Sciences. 121, p. 301-308 8 p.

Research output: Article

Protective Agents
Itraconazole
Crystallization
Pharmaceutical Preparations
Powders

Application of melt-blown Poly(lactic acid) fibres in self-reinforced composites

Vadas, D., Kmetykó, D., Marosi, G. & Bocz, K., júl. 12 2018, In : Polymers. 10, 7, 766.

Research output: Article

Lactic acid
Fibers
Composite materials
Mechanical properties
Blow molding
18 Citations (Scopus)

Continuous end-to-end production of solid drug dosage forms: Coupling flow synthesis and formulation by electrospinning

Balogh, A., Domokos, A., Farkas, B., Farkas, A., Rapi, Z., Kiss, D., Nyiri, Z., Eke, Z., Szarka, G., Örkényi, R., Mátravölgyi, B., Faigl, F., Marosi, G. & Nagy, Z. K., okt. 15 2018, In : Chemical Engineering Journal. 350, p. 290-299 10 p.

Research output: Article

Drug dosage
Dosage Forms
Electrospinning
drug
Aspirin
8 Citations (Scopus)

Flame retardancy of microcellular poly(lactic acid) foams prepared by supercritical CO2-assisted extrusion

Vadas, D., Igricz, T., Sarazin, J., Bourbigot, S., Marosi, G. & Bocz, K., júl. 1 2018, In : Polymer Degradation and Stability. 153, p. 100-108 9 p.

Research output: Article

Flame Retardants
flame retardants
lactic acid
Flame retardants
Lactic acid
1 Citation (Scopus)

Flame retarded self-reinforced polypropylene composites prepared by injection moulding

Vadas, D., Kmetty, Á., Bárány, T., Marosi, G. & Bocz, K., jan. 1 2018, In : Polymers for Advanced Technologies. 29, 1, p. 433-441 9 p.

Research output: Article

Flame Retardants
Polypropylenes
Flame retardants
Injection molding
Composite materials
2 Citations (Scopus)

Homogenization of amorphous solid dispersions prepared by electrospinning in low-dose tablet formulation

Fülöp, G., Balogh, A., Farkas, B., Farkas, A., Szabó, B., Démuth, B., Borbás, E., Nagy, Z. K. & Marosi, G., szept. 1 2018, In : Pharmaceutics. 10, 3, 114.

Research output: Article

Tablets
Pharmaceutical Preparations
Electron Scanning Microscopy
Powders
Plastics
7 Citations (Scopus)

Medicated straws based on electrospun solid dispersions

Farkas, B., Balogh, A., Farkas, A., Domokos, A., Borbás, E., Marosi, G. & Nagy, Z. K., máj. 16 2018, In : Periodica Polytechnica Chemical Engineering. 62, 3, p. 310-316 7 p.

Research output: Article

Straw
Electrospinning
Dispersions
Pharmaceutical Preparations
Povidone
1 Citation (Scopus)
Polypropylenes
X ray scattering
Raman spectroscopy
Composite materials
Elastic moduli
2 Citations (Scopus)

Pharmaceutical and macromolecular technologies in the spirit of industry 4.0

Marosi, G., Hirsch, E., Bocz, K., Toldy, A., Szolnoki, B., Bodzay, B., Csontos, I., Farkas, A., Balogh, A., Démuth, B., Nagy, Z. K. & Pataki, H., nov. 20 2018, In : Periodica Polytechnica Chemical Engineering. 62, 4, p. 457-466 10 p.

Research output: Article

Flame Retardants
Biopolymers
Flame retardants
Drug products
Polycaprolactone
2 Citations (Scopus)

Preparation and characterization of biocompatible electrospun nanofiber scaffolds

Hirsch, E., Nacsa, M., Ender, F., Mohai, M., Nagy, Z. K. & Marosi, G., nov. 20 2018, In : Periodica Polytechnica Chemical Engineering. 62, 4, p. 510-518 9 p.

Research output: Article

Nanofibers
Scaffolds
Fabrication
Hydroxybutyrates
Enzyme immobilization
2 Citations (Scopus)
Foams
Polymerization
Viscosity
Polyethylene Terephthalates
Polycondensation
4 Citations (Scopus)
Drug products
Tablets
Pharmaceutical Preparations
Spironolactone
Imipramine
4 Citations (Scopus)

Real-time feedback control of twin-screw wet granulation based on image analysis

Madarász, L., Nagy, Z. K., Hoffer, I., Szabó, B., Csontos, I., Pataki, H., Démuth, B., Szabó, B., Csorba, K. & Marosi, G., aug. 25 2018, In : International Journal of Pharmaceutics. 547, 1-2, p. 360-367 8 p.

Research output: Article

Particle Size
Pharmaceutical Technology
Lactose
Starch
Software
14 Citations (Scopus)

Scaled-up preparation of drug-loaded electrospun polymer fibres and investigation of their continuous processing to tablet form

Szabó, E., Démuth, B., Nagy, B., Molnár, K., Farkas, A., Szabó, B., Balogh, A., Hirsch, E., Nagy, B., Marosi, G. & Nagy, Z. K., máj. 1 2018, In : Express Polymer Letters. 12, 5, p. 436-451 16 p.

Research output: Article

tablets
Dispersions
Tablets
Polymers
drugs
8 Citations (Scopus)

Spectroscopic characterization of tablet properties in a continuous powder blending and tableting process

Nagy, B., Farkas, A., Magyar, K., Démuth, B., Nagy, Z. K. & Marosi, G., okt. 15 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 10-19 10 p.

Research output: Article

Near-Infrared Spectroscopy
Powders
Raman Spectrum Analysis
Tablets
Lubrication
2017
17 Citations (Scopus)

Controlled-release solid dispersions of Eudragit® FS 100 and poorly soluble spironolactone prepared by electrospinning and melt extrusion

Balogh, A., Farkas, B., Domokos, A., Farkas, A., Démuth, B., Borbás, E., Nagy, B., Marosi, G. & Nagy, Z. K., okt. 1 2017, In : European Polymer Journal. 95, p. 406-417 12 p.

Research output: Article

Spironolactone
Electrospinning
Dispersions
Extrusion
drugs
16 Citations (Scopus)

Development and tableting of directly compressible powder from electrospun nanofibrous amorphous solid dispersion

Démuth, B., Farkas, A., Szabó, B., Balogh, A., Nagy, B., Vágó, E., Vigh, T., Tinke, A. P., Kazsu, Z., Demeter, Bertels, J., Mensch, J., Van Dijck, A., Verreck, G., Van Assche, I., Marosi, G. & Nagy, Z. K., jún. 1 2017, In : Advanced Powder Technology. 28, 6, p. 1554-1563 10 p.

Research output: Article

Powders
Tablets
Compaction
Fillers
Atmospheric humidity
7 Citations (Scopus)

Flame retardancy of carbon fibre reinforced sorbitol based bioepoxy composites with phosphorus-containing additives

Toldy, A., Niedermann, P., Pomázi, Á., Marosi, G. & Szolnoki, B., jan. 1 2017, In : Materials. 10, 5, 467.

Research output: Article

Flame Retardants
Sorbitol
Flame retardants
Phosphorus
Carbon fibers
14 Citations (Scopus)

Immobilization engineering-How to design advanced sol-gel systems for biocatalysis?

Weiser, D., Nagy, F., Bánóczi, G., Oláh, M., Farkas, A., Szilágyi, A., László, K., Gellért, Á., Marosi, G., Kemény, S. & Poppe, L., jan. 1 2017, In : Green Chemistry. 19, 16, p. 3927-3937 11 p.

Research output: Article

immobilization
Sol-gels
gel
engineering
Enzymes
26 Citations (Scopus)

In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process

Nagy, B., Farkas, A., Gyürkés, M., Komaromy-Hiller, S., Démuth, B., Szabó, B., Nusser, D., Borbás, E., Marosi, G. & Nagy, Z. K., szept. 15 2017, In : International Journal of Pharmaceutics. 530, 1-2, p. 21-29 9 p.

Research output: Article

Powders
Raman Spectrum Analysis
Pharmaceutical Preparations
Technology
Pharmaceutical Technology
8 Citations (Scopus)

Investigation of Deteriorated Dissolution of Amorphous Itraconazole: Description of Incompatibility with Magnesium Stearate and Possible Solutions

Démuth, B., Galata, D. L., Szabó, E., Nagy, B., Farkas, A., Balogh, A., Hirsch, E., Pataki, H., Rapi, Z., Bezúr, L., Vigh, T., Verreck, G., Szalay, Z., Demeter, Marosi, G. & Nagy, Z. K., nov. 6 2017, In : Molecular Pharmaceutics. 14, 11, p. 3927-3934 8 p.

Research output: Article

Itraconazole
Tablets
Lubricants
Hydrogen Bonding
Crystallization
12 Citations (Scopus)

Novel Alternating Current Electrospinning of Hydroxypropylmethylcellulose Acetate Succinate (HPMCAS) Nanofibers for Dissolution Enhancement: The Importance of Solution Conductivity

Balogh, A., Farkas, B., Pálvölgyi, Á., Domokos, A., Démuth, B., Marosi, G. & Nagy, Z. K., jún. 1 2017, In : Journal of Pharmaceutical Sciences. 106, 6, p. 1634-1643 10 p.

Research output: Article

hydroxypropylmethylcellulose acetate succinate
Nanofibers
Spironolactone
calcium acetate
Sodium Dodecyl Sulfate
9 Citations (Scopus)

Oral bioavailability enhancement of flubendazole by developing nanofibrous solid dosage forms

Vigh, T., Démuth, B., Balogh, A., Galata, D. L., Van Assche, I., Mackie, C., Vialpando, M., Van Hove, B., Psathas, P., Borbás, E., Pataki, H., Boeykens, P., Marosi, G., Verreck, G. & Nagy, Z. K., márc. 8 2017, (Accepted/In press) In : Drug Development and Industrial Pharmacy. p. 1-8 8 p.

Research output: Article

Dosage Forms
Biological Availability
Ocular Onchocerciasis
Elephantiasis
Crystalline materials
3 Citations (Scopus)

Variable clustering and spectral angle mapper-orthogonal projection method for Raman mapping of compound detection in tablets

Farkas, A., Nagy, B., Démuth, B., Balogh, A., Pataki, H., Nagy, Z. K. & Marosi, G., jan. 1 2017, In : Journal of Chemometrics. 31, 1, e2861.

Research output: Article

Orthogonal Projection
Raman
Projection Method
Clustering algorithms
Tablets
2016
17 Citations (Scopus)

AC and DC electrospinning of hydroxypropylmethylcellulose with polyethylene oxides as secondary polymer for improved drug dissolution

Balogh, A., Farkas, B., Verreck, G., Mensch, J., Borbás, E., Nagy, B., Marosi, G. & Nagy, Z. K., máj. 30 2016, In : International Journal of Pharmaceutics. 505, 1-2, p. 159-166 8 p.

Research output: Article

Polymers
Spironolactone
Pharmaceutical Preparations
Drug Compounding
Drug Delivery Systems
29 Citations (Scopus)

Detailed stability investigation of amorphous solid dispersions prepared by single-needle and high speed electrospinning

Démuth, B., Farkas, A., Pataki, H., Balogh, A., Szabó, B., Borbás, E., Sóti, P. L., Vigh, T., Kiserdei, Farkas, B., Mensch, J., Verreck, G., Van Assche, I., Marosi, G. & Nagy, Z. K., febr. 10 2016, In : International Journal of Pharmaceutics. 498, 1-2, p. 234-244 11 p.

Research output: Article

Itraconazole
Needles
Humidity
Hydrogen
Povidone
3 Citations (Scopus)
Tetramisole
Enantiomers
enantiomers
Ternary systems
ternary systems
21 Citations (Scopus)

Electrospun polylactic acid and polyvinyl alcohol fibers as efficient and stable nanomaterials for immobilization of lipases

Sóti, P. L., Weiser, D., Vigh, T., Nagy, Z. K., Poppe, L. & Marosi, G., márc. 1 2016, In : Bioprocess and Biosystems Engineering. 39, 3, p. 449-459 11 p.

Research output: Article

Polyvinyl Alcohol
Nanostructures
Polyvinyl alcohols
Lipases
Lipase
7 Citations (Scopus)

Flame retardancy of sorbitol based bioepoxy via combined solid and gas phase action

Szolnoki, B., Bocz, K., Marosi, G. & Toldy, A., aug. 30 2016, In : Polymers. 8, 9, 322.

Research output: Article

Polyphosphates
Sorbitol
Ammonium Compounds
Ether
Ethers
5 Citations (Scopus)
Flame Retardants
Polypropylenes
Flame retardants
Composite materials
Fibers
13 Citations (Scopus)

Lubricant-Induced Crystallization of Itraconazole From Tablets Made of Electrospun Amorphous Solid Dispersion

Démuth, B., Farkas, A., Balogh, A., Bartosiewicz, K., Kállai-Szabó, B., Bertels, J., Vigh, T., Mensch, J., Verreck, G., Van Assche, I., Marosi, G. & Nagy, Z. K., szept. 1 2016, In : Journal of Pharmaceutical Sciences. 105, 9, p. 2982-2988 7 p.

Research output: Article

Lubricants
Itraconazole
Crystallization
Tablets
Povidone
Polymers
Bioengineering
4 Citations (Scopus)

Quantification and handling of nonlinearity in Raman micro-spectrometry of pharmaceuticals

Nagy, B., Farkas, A., Balogh, A., Pataki, H., Vajna, B., Nagy, Z. K. & Marosi, G., szept. 5 2016, In : Journal of Pharmaceutical and Biomedical Analysis. 128, p. 236-246 11 p.

Research output: Article

Spectrometry
Spectrum Analysis
Pharmaceutical Preparations
Least-Squares Analysis
Crystalline materials
8 Citations (Scopus)

Raman-Based Feedback Control of the Enzymatic Hydrolysis of Lactose

Hirsch, E., Pataki, H., Farkas, A., Bata, H., Vass, P., Fehér, C., Barta, Z., Párta, L., Csontos, I., Ballagi, A., Nagy, Z. K. & Marosi, G., okt. 21 2016, In : Organic Process Research and Development. 20, 10, p. 1721-1727 7 p.

Research output: Article

lactose
Enzymatic hydrolysis
Lactose
feedback control
Feedback control
4 Citations (Scopus)

Synthesis of a self-assembling gold nanoparticle-supported organocatalyst for enamine-based asymmetric aldol reactions

Sóti, P. L., Yamashita, H., Sato, K., Narumi, T., Toda, M., Watanabe, N., Marosi, G. & Mase, N., jan. 6 2016, (Accepted/In press) In : Tetrahedron.

Research output: Article

Proline
Gold
Nanoparticles
Benzaldehydes
Hydroxyproline
2015
22 Citations (Scopus)

Alternating current electrospinning for preparation of fibrous drug delivery systems

Balogh, A., Cselkó, R., Démuth, B., Verreck, G., Mensch, J., Marosi, G. & Nagy, Z. K., nov. 10 2015, In : International Journal of Pharmaceutics. 495, 1, p. 75-80 6 p.

Research output: Article

Drug Delivery Systems
Pharmaceutical Preparations
Nanofibers
Povidone
Drug Compounding