• 3017 Citations
  • 26 h-Index
20002020

Research output per year

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Research Output

  • 3017 Citations
  • 26 h-Index
  • 37 Article
  • 5 Review article
  • 1 Chapter
  • 1 Short survey
2020
1 Citation (Scopus)
Open Access
2019

Identification of anticancer OATP2B1 substrates by an in vitro triple-fluorescence-based cytotoxicity screen

Windt, T., Tóth, S., Patik, I., Sessler, J., Kucsma, N., Szepesi, Á., Zdrazil, B., Özvegy-Laczka, C. & Szakács, G., jan. 1 2019, In : Archives of Toxicology.

Research output: Article

Open Access
2 Citations (Scopus)
2018
8 Citations (Scopus)

Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography

Bauer, M., Matsuda, A., Wulkersdorfer, B., Philippe, C., Traxl, A., Özvegy-Laczka, C., Stanek, J., Nics, L., Klebermass, E. M., Poschner, S., Jäger, W., Patik, I., Bakos, É., Szakács, G., Wadsak, W., Hacker, M., Zeitlinger, M. & Langer, O., júl. 2018, In : Clinical Pharmacology and Therapeutics. 104, 1, p. 139-147 9 p.

Research output: Article

19 Citations (Scopus)

Pd-Catalyzed microwave-assisted synthesis of phosphonated 13α-estrones as potential OATP2B1, 17β-HSD1 and/or STS inhibitors

Jójárt, R., Pécsy, S., Keglevich, G., Szécsi, M., Rigó, R., Ozvegy-Laczka, C., Kecskeméti, G. & Mernyák, E., nov. 14 2018, In : Beilstein Journal of Organic Chemistry. 14, p. 2838-2845 8 p.

Research output: Article

4 Citations (Scopus)
2017

The importance of steroid uptake and intracrine action in endometrial and ovarian cancers

Rižner, T. L., Thalhammer, T. & özvegy-Laczka, C., 2017, In : Frontiers in Pharmacology. 8, JUN, 346.

Research output: Review article

15 Citations (Scopus)
25 Citations (Scopus)
2015

Functional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate

Patik, I., Kovacsics, D., Német, O., Gera, M., Várady, G., Stieger, B., Hagenbuch, B., Szakács, G. & Özvegy-Laczka, C., dec. 15 2015, In : Biochemical Pharmacology. 98, 4, p. 649-658 10 p.

Research output: Article

13 Citations (Scopus)

Lipid Regulation of the ABCB1 and ABCG2 Multidrug Transporters

Hegedüs, C., Telbisz, Á., Hegedus, T., Sarkadi, B. & Özvegy-Laczka, C., jan. 1 2015, Advances in Cancer Research. Academic Press Inc., p. 97-137 41 p. (Advances in Cancer Research; vol. 125).

Research output: Chapter

19 Citations (Scopus)
14 Citations (Scopus)
2014
24 Citations (Scopus)
2013
9 Citations (Scopus)
20 Citations (Scopus)
28 Citations (Scopus)

Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2

Winter, E., Lecerf-Schmidt, F., Gozzi, G., Peres, B., Lightbody, M., Gauthier, C., Ozvegy-Laczka, C., Szakacs, G., Sarkadi, B., Creczynski-Pasa, T. B., Boumendjel, A. & Di Pietro, A., dec. 27 2013, In : Journal of Medicinal Chemistry. 56, 24, p. 9849-9860 12 p.

Research output: Article

26 Citations (Scopus)
2012

Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter

Telbisz, Á., Hegedüs, C., Özvegy-Laczka, C., Goda, K., Várady, G., Takáts, Z., Szabó, E., Sorrentino, B. P., Váradi, A. & Sarkadi, B., jan. 23 2012, In : European Journal of Pharmaceutical Sciences. 45, 1-2, p. 101-109 9 p.

Research output: Article

17 Citations (Scopus)
45 Citations (Scopus)

PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter

Hegedüs, C., Truta-Feles, K., Antalffy, G., Brózik, A., Kasza, I., Német, K., Orbán, T. I., Özvegy-Laczka, C., Váradi, A. & Sarkadi, B., ápr. 20 2012, In : Biochemical and biophysical research communications. 420, 4, p. 869-874 6 p.

Research output: Article

14 Citations (Scopus)
2011
85 Citations (Scopus)
2009

Arginine 383 is a crucial residue in ABCG2 biogenesis

Polgar, O., Ediriwickrema, L. S., Robey, R. W., Sharma, A., Hegde, R. S., Li, Y., Xia, D., Ward, Y., Dean, M., Ozvegy-Laczka, C., Sarkadi, B. & Bates, S. E., júl. 1 2009, In : Biochimica et Biophysica Acta - Biomembranes. 1788, 7, p. 1434-1443 10 p.

Research output: Article

17 Citations (Scopus)
36 Citations (Scopus)
154 Citations (Scopus)
2008
16 Citations (Scopus)

Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter

Özvegy-Laczka, C., Laczko, R., Hegedus, C., Litman, T., Várady, G., Goda, K., Hegedus, T., Dokholyan, N. V., Sorrentino, B. P., Váradi, A. & Sarkadi, B., szept. 19 2008, In : Journal of Biological Chemistry. 283, 38, p. 26059-26070 12 p.

Research output: Article

30 Citations (Scopus)
329 Citations (Scopus)
2007
93 Citations (Scopus)
2006

Mutational studies of G553 in TM5 of ABCG2: A residue potentially involved in dimerization

Polgar, O., Ozvegy-Laczka, C., Robey, R. W., Morisaki, K., Okada, M., Tamaki, A., Koblos, G., Elkind, N. B., Ward, Y., Dean, M., Sarkadi, B. & Bates, S. E., ápr. 25 2006, In : Biochemistry. 45, 16, p. 5251-5260 10 p.

Research output: Article

30 Citations (Scopus)
136 Citations (Scopus)
34 Citations (Scopus)
2005

Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface

Özvegy-Laczka, C., Várady, G., Köblös, G., Ujhelly, O., Cervenak, J., Schuetz, J. D., Sorrentino, B. P., Koomen, G. J., Váradi, A., Német, K. & Sarkadi, B., febr. 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4219-4227 9 p.

Research output: Article

67 Citations (Scopus)
195 Citations (Scopus)
66 Citations (Scopus)

Single nucleotide polymorphisms modify the transporter activity of ABCG2

Morisaki, K., Robey, R. W., Özvegy-Laczka, C., Honjo, Y., Polgar, O., Steadman, K., Sarkadi, B. & Bates, S. E., aug. 1 2005, In : Cancer Chemotherapy And Pharmacology. 56, 2, p. 161-172 12 p.

Research output: Article

173 Citations (Scopus)
109 Citations (Scopus)
2004

ABCG2 - A transporter for all seasons

Sarkadi, B., Özvegy-Laczka, C., Német, K. & Váradi, A., jún. 1 2004, In : FEBS letters. 567, 1, p. 116-120 5 p.

Research output: Article

225 Citations (Scopus)

Functional expression and characterization of the human ABCG1 and ABCG4 proteins: Indications for heterodimerization

Cserepes, J., Szentpétery, Z., Seres, L., Özvegy-Laczka, C., Langmann, T., Schmitz, G., Glavinas, H., Klein, I., Homolya, L., Váradi, A., Sarkadi, B. & Elkind, N. B., júl. 30 2004, In : Biochemical and biophysical research communications. 320, 3, p. 860-867 8 p.

Research output: Article

69 Citations (Scopus)
279 Citations (Scopus)
2003

Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells

Ujhelly, O., Özvegy, C., Várady, G., Cervenak, J., Homolya, L., Grez, M., Scheffer, G., Roos, D., Bates, S. E., Váradi, A., Sarkadi, B. & Német, K., márc. 1 2003, In : Human Gene Therapy. 14, 4, p. 403-412 10 p.

Research output: Article

31 Citations (Scopus)
2002
181 Citations (Scopus)
2001
44 Citations (Scopus)
248 Citations (Scopus)
41 Citations (Scopus)
2000
26 Citations (Scopus)