• 4608 Citations
  • 35 h-Index
19952019

Research output per year

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Research Output

  • 4608 Citations
  • 35 h-Index
  • 62 Article
  • 7 Review article
  • 1 Comment/debate
  • 1 Editorial
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Article
9 Citations (Scopus)

American thyroid association guide to investigating thyroid hormone economy and action in rodent and cell models

Bianco, A. C., Anderson, G., Forrest, D., Galton, V. A., Gereben, B., Kim, B. W., Kopp, P. A., Liao, X. H., Obregon, M. J., Peeters, R. P., Refetoff, S., Sharlin, D. S., Simonides, W. S., Weiss, R. E. & Williams, G. R., jan. 1 2014, In : Thyroid. 24, 1, p. 88-168 81 p.

Research output: Article

99 Citations (Scopus)

A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons

Kalló, I., Mohácsik, P., Vida, B., Zeöld, A., Bardóczi, Z., Zavacki, A. M., Farkas, E., Kádár, A., Hrabovszky, E., Arrojo e Drigo, R., Dong, L., Barna, L., Palkovits, M., Borsay, B. A., Herczeg, L., Lechan, R. M., Bianco, A. C., Liposits, Z., Fekete, C. & Gereben, B., jún. 18 2012, In : PloS one. 7, 6, e37860.

Research output: Article

32 Citations (Scopus)

A transgenic mouse model for detection of tissue-specific thyroid hormone action

Mohácsik, P., Erdélyi, F., Baranyi, M., Botz, B., Szabó, G., Tóth, M., Haltrich, I., Helyes, Z., Sperlágh, B., Tóth, Z., Sinkó, R., Lechan, R. M., Bianco, A. C., Fekete, C. & Gereben, B., febr. 2018, In : Endocrinology. 159, 2, p. 1159-1171 13 p.

Research output: Article

4 Citations (Scopus)

A unique haplotype of RCCX copy number variation: From the clinics of congenital adrenal hyperplasia to evolutionary genetics

Doleschall, M., Luczay, A., Koncz, K., Hadzsiev, K., Erhardt, É., Szilágyi, Á., Doleschall, Z., Németh, K., Török, D., Prohászka, Z., Gereben, B., Fekete, G., Gláz, E., Igaz, P., Korbonits, M., Tóth, M., Rácz, K. & Patócs, A., ápr. 12 2017, In : European Journal of Human Genetics. 25, 6, p. 702-710 9 p.

Research output: Article

2 Citations (Scopus)

Characterization of the 5′-flanking and 5′-untranslated regions of the cyclic adenosine 3′,5′-monophosphate-responsive human type 2 iodothyronine deiodinase gene

Bartha, T., Kim, S. W., Salvatore, D., Gereben, B., Tu, H. M., Harney, J. W., Rudas, P. & Reed Larsen, P., jan. 1 2000, In : Endocrinology. 141, 1, p. 229-237 9 p.

Research output: Article

94 Citations (Scopus)

Characterization of the nuclear factor-κB responsiveness of the human dio2 gene

Zeöld, A., Doleschall, M., Haffner, M. C., Capelo, L. P., Menyhért, J., Liposits, Z., Da Silva, W. S., Bianco, A. C., Kacskovics, I., Fekete, C. & Gereben, B., 2006, In : Endocrinology. 147, 9, p. 4419-4429 11 p.

Research output: Article

55 Citations (Scopus)

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Yavari, A., Stocker, C. J., Ghaffari, S., Wargent, E. T., Steeples, V., Czibik, G., Pinter, K., Bellahcene, M., Woods, A., Martínez De Morentin, P. B., Cansell, C., Lam, B. Y. H., Chuster, A., Petkevicius, K., Nguyen-Tu, M. S., Martinez-Sanchez, A., Pullen, T. J., Oliver, P. L., Stockenhuber, A., Nguyen, C. & 34 others, Lazdam, M., O'Dowd, J. F., Harikumar, P., Tóth, M., Beall, C., Kyriakou, T., Parnis, J., Sarma, D., Katritsis, G., Wortmann, D. D. J., Harper, A. R., Brown, L. A., Willows, R., Gandra, S., Poncio, V., De Oliveira Figueiredo, M. J., Qi, N. R., Peirson, S. N., McCrimmon, R. J., Gereben, B., Tretter, L., Fekete, C., Redwood, C., Yeo, G. S. H., Heisler, L. K., Rutter, G. A., Smith, M. A., Withers, D. J., Carling, D., Sternick, E. B., Arch, J. R. S., Cawthorne, M. A., Watkins, H. & Ashrafian, H., máj. 10 2016, In : Cell Metabolism. 23, 5, p. 821-836 16 p.

Research output: Article

48 Citations (Scopus)

Chronic cardiac-specific thyrotoxicosis increases myocardial β-adrenergic responsiveness

Carvalho-Bianco, S. D., Kim, B. W., Zhang, J. X., Harney, J. W., Ribeiro, R. S., Gereben, B., Bianco, A. C., Mende, U. & Larsen, P. R., júl. 1 2004, In : Molecular Endocrinology. 18, 7, p. 1840-1849 10 p.

Research output: Article

41 Citations (Scopus)

Cloning and expression of the chicken type 2 iodothyronine 5'- deiodinase

Gereben, B., Bartha, T., Tu, H. M., Harney, J. W., Rudas, P. & Larsen, P. R., máj. 14 1999, In : Journal of Biological Chemistry. 274, 20, p. 13768-13776 9 p.

Research output: Article

69 Citations (Scopus)

Cloning and functional characterization of an uncoupling protein homolog in hummingbirds

Vianna, C. R., Hagen, T., Zhang, C. Y., Bachman, E., Boss, O., Gereben, B., Moriscot, A. S., Lowell, B. B., Bicudo, J. E. P. W. & Bianco, A. C., jún. 2001, In : Physiological Genomics. 2001, 5, p. 137-145 9 p.

Research output: Article

69 Citations (Scopus)

Coordination of hypothalamic and pituitary T3 production regulates TSH expression

Fonseca, T. L., Correa-Medina, M., Campos, M. P. O., Wittmann, G., Werneck-de-Castro, J. P., Drigo, R. A., Mora-Garzon, M., Ueta, C. B., Caicedo, A., Fekete, C., Gereben, B., Lechan, R. M. & Bianco, A. C., ápr. 1 2013, In : Journal of Clinical Investigation. 123, 4, p. 1492-1500 9 p.

Research output: Article

86 Citations (Scopus)

Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation

Curcio-Morelli, C., Zavacki, A. M., Christofollete, M., Gereben, B., De Freitas, B. C. G., Harney, J. W., Li, Z., Wu, G. & Bianco, A. C., júl. 2003, In : Journal of Clinical Investigation. 112, 2, p. 189-196 8 p.

Research output: Article

101 Citations (Scopus)

Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine

De Castro, J. P. W., Fonseca, T. L., Ueta, C. B., McAninch, E. A., Abdalla, S., Wittmann, G., Lechan, R. M., Gereben, B. & Bianco, A. C., febr. 2 2015, In : Journal of Clinical Investigation. 125, 2, p. 769-781 13 p.

Research output: Article

69 Citations (Scopus)

Different Types of Luciferase Reporters Show Distinct Susceptibility to T3-Evoked Downregulation

Kollár, A., Kvárta-Papp, Z., Egri, P. & Gereben, B., jan. 1 2016, In : Thyroid. 26, 1, p. 179-182 4 p.

Research output: Article

3 Citations (Scopus)

Distinct subcellular localization of transiently expressed types 1 and 2 iodothyronine deiodinases as determined by immunofluorescence confocal microscopy

Baqui, M. M. A., Gereben, B., Harney, J. W., Larsen, P. R. & Bianco, A. C., jan. 1 2000, In : Endocrinology. 141, 11, p. 4309-4312 4 p.

Research output: Article

Open Access
96 Citations (Scopus)

Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function

Ignacio, D. L., Silvestre, D. H. S., Anne-Palmer, E., Bocco, B. M. L. C., Fonseca, T. L., Ribeiro, M. O., Gereben, B., Bianco, A. C. & Werneck-De-Castro, J. P., ápr. 2017, In : Thyroid. 27, 4, p. 577-586 10 p.

Research output: Article

7 Citations (Scopus)

Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eiF2a-mediated decrease in type 2 deiodinase synthesis

e Drigo, R. A., Fonseca, T. L., Castillo, M., Salathe, M., Simovic, G., Mohácsik, P., Gereben, B. & Bianco, A. C., dec. 2011, In : Molecular Endocrinology. 25, 12, p. 2065-2075 11 p.

Research output: Article

21 Citations (Scopus)
16 Citations (Scopus)

Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain

Fekete, C., Freitas, B. C. G., Zeöld, A., Wittmann, G., Kádár, A., Liposits, Z., Christoffolete, M. A., Singru, P., Lechan, R. M., Bianco, A. C. & Gereben, B., okt. 1 2007, In : Endocrinology. 148, 10, p. 4865-4874 10 p.

Research output: Article

28 Citations (Scopus)

Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis

Fonseca, T. L., Fernandes, G. W., Bocco, B. M. L. C., Keshavarzian, A., Jakate, S., Donohue, T. M., Gereben, B. & Bianco, A. C., júl. 2019, In : Alcoholism: Clinical and Experimental Research. 43, 7, p. 1376-1383 8 p.

Research output: Article

1 Citation (Scopus)

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

Jansen, S. W., Akintola, A. A., Roelfsema, F., Van Der Spoel, E., Cobbaert, C. M., Ballieux, B. E., Egri, P., Kvarta-Papp, Z., Gereben, B., Fekete, C., Slagboom, P. E., Van Der Grond, J., Demeneix, B. A., Pijl, H., Westendorp, R. G. J. & Van Heemst, D., jún. 19 2015, In : Scientific reports. 5, 11525.

Research output: Article

37 Citations (Scopus)

Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes

Baqui, M., Botero, D., Gereben, B., Curcio, C., Harney, J. W., Salvatore, D., Sorimachi, K., Larsen, P. R. & Bianco, A. C., jan. 10 2003, In : Journal of Biological Chemistry. 278, 2, p. 1206-1211 6 p.

Research output: Article

95 Citations (Scopus)

Increased thyroid hormone activation accompanies the formation of thyroid hormone-dependent negative feedback in developing chicken hypothalamus

Mohácsik, P., Füzesi, T., Doleschall, M., Szilvásy-Szabó, A., Vancamp, P., Hadadi, Darras, V. M., Fekete, C. & Gereben, B., márc. 2016, In : Endocrinology. 157, 3, p. 1211-1221 11 p.

Research output: Article

3 Citations (Scopus)

Interleukin-6 Receptor α is Co-localised with Melanin-Concentrating Hormone in Human and Mouse Hypothalamus

Schéle, E., Fekete, C., Egri, P., Füzesi, T., Palkovits, M., Keller, É., Liposits, Z., Gereben, B., Karlsson-Lindahl, L., Shao, R. & Jansson, J. O., jún. 2012, In : Journal of Neuroendocrinology. 24, 6, p. 930-943 14 p.

Research output: Article

21 Citations (Scopus)

Inverse hierarchy of vimentin epitope expression in primary cultures of chicken and rat astrocytes: A double-immunofluorescence study

Gereben, B., Leuhuber, K., Rausch, W. D., Galfi, P., Jancsik, V. & Rudas, P., dec. 1 1998, In : NEUROBIOLOGY. 6, 2, p. 141-150 10 p.

Research output: Article

4 Citations (Scopus)

In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases

Curcio-Morelli, C., Gereben, B., Zavacki, A. M., Kim, B. W., Huang, S., Harney, J. W., Larsen, P. R. & Bianco, A. C., márc. 1 2003, In : Endocrinology. 144, 3, p. 937-946 10 p.

Research output: Article

53 Citations (Scopus)

KISS1R intracellular trafficking and degradation: Effect of the Arg386Pro disease-associated mutation

Bianco, S. D. C., Vandepas, L., Correa-Medina, M., Gereben, B., Mukherjee, A., Kuohung, W., Carroll, R., Teles, M. G., Latronico, A. C. & Kaiser, U. B., ápr. 2011, In : Endocrinology. 152, 4, p. 1616-1626 11 p.

Research output: Article

38 Citations (Scopus)

Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells

Aerts, G., Drigo, R. A., Van Herck, S. L. J., Sammels, E., Mirebeau-Prunier, D., Gereben, B., Zeöld, A., Harney, J. W., Huang, S. A., Mulcahey, M. A., Van Der Geyten, S., Van Den Bergh, G., Arckens, L., Darras, V. M. & Zavacki, A. M., nov. 2009, In : Endocrinology. 150, 11, p. 5171-5180 10 p.

Research output: Article

2 Citations (Scopus)
32 Citations (Scopus)

Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: Implications for the nonthyroidal illness syndrome

Fekete, C., Gereben, B., Doleschall, M., Harney, J. W., Dora, J. M., Bianco, A. C., Sarkar, S., Liposits, Z., Rand, W., Emerson, C., Kacskovics, I., Reed Larsen, P. & Lechan, R. M., ápr. 2004, In : Endocrinology. 145, 4, p. 1649-1655 7 p.

Research output: Article

140 Citations (Scopus)

Metabolic instability of type 2 deiodinase is transferable to stable proteins independently of subcellular localization

Zeöld, A., Pormüller, L., Dentice, M., Harney, J. W., Curcio-Morelli, C., Tente, S. M., Bianco, A. C. & Gereben, B., okt. 20 2006, In : Journal of Biological Chemistry. 281, 42, p. 31538-31543 6 p.

Research output: Article

37 Citations (Scopus)
7 Citations (Scopus)

Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism

Jo, S., Kalló, I., Bardóczi, Z., e Drigo, R. A., Zeöld, A., Liposits, Z., Oliva, A., Lemmon, V. P., Bixby, J. L., Gereben, B. & Bianco, A. C., jún. 20 2012, In : Journal of Neuroscience. 32, 25, p. 8491-8500 10 p.

Research output: Article

44 Citations (Scopus)

Ontogenic redistribution of type 2 deiodinase messenger ribonucleic acid in the brain of chicken

Gereben, B., Pachucki, J., Kollár, A., Liposits, Z. & Fekete, C., aug. 2004, In : Endocrinology. 145, 8, p. 3619-3625 7 p.

Research output: Article

35 Citations (Scopus)

Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells

Freitas, B. C. G., Gereben, B., Castillo, M., Kalló, I., Zeöld, A., Egri, P., Liposits, Z., Zavacki, A. M., Maciel, R. M. B., Jo, S., Singru, P., Sanchez, E., Lechan, R. M. & Bianco, A. C., jún. 1 2010, In : Journal of Clinical Investigation. 120, 6, p. 2206-2217 12 p.

Research output: Article

102 Citations (Scopus)

Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents

Wittmann, G., Szabon, J., Mohácsik, P., Nouriel, S. S., Gereben, B., Fekete, C. & Lechan, R. M., ápr. 1 2015, In : Endocrinology. 156, 4, p. 1552-1564 13 p.

Research output: Article

16 Citations (Scopus)

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity

Fonseca, T. L., Fernandes, G. W., McAninch, E. A., Bocco, B. M. L. C., Abdalla, S. M., Ribeiro, M. O., Mohácsik, P., Fekete, C., Li, D., Xing, X., Wang, T., Gereben, B. & Bianco, A. C., nov. 10 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 45, p. 14018-14023 6 p.

Research output: Article

Open Access
13 Citations (Scopus)

Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates the hypothalamo-pituitary-thyroid (HPT) axis via type 2 deiodinase in male mice

Egri, P., Fekete, C., Dénes, Reglodi, D., Hashimoto, H., Fülöp, B. D. & Gereben, B., jún. 2016, In : Endocrinology. 157, 6, p. 2356-2366 11 p.

Research output: Article

14 Citations (Scopus)

Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes

McAninch, E. A., Jo, S., Preite, N. Z., Farkas, E., Mohácsik, P., Fekete, C., Egri, P., Gereben, B., Li, Y., Deng, Y., Patti, M. E., Zevenbergen, C., Peeters, R. P., Mash, D. C. & Bianco, A. C., márc. 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 3, p. 920-933 14 p.

Research output: Article

37 Citations (Scopus)

Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway

Christoffolete, M. A., Doleschall, M., Egri, P., Liposits, Z., Zavacki, A. M., Bianco, A. C. & Gereben, B., máj. 2010, In : Journal of Endocrinology. 205, 2, p. 179-186 8 p.

Research output: Article

23 Citations (Scopus)

Selective proteolysis of human type 2 deiodinase: A novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation

Gereben, B., Goncalves, C., Harney, J. W., Larsen, P. R. & Bianco, A. C., jan. 1 2000, In : Molecular Endocrinology. 14, 11, p. 1697-1708 12 p.

Research output: Article

Open Access
116 Citations (Scopus)
7 Citations (Scopus)
11 Citations (Scopus)

The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase

Zavacki, A. M., E Drigo, R. A., Freitas, B. C. G., Chung, M., Harney, J. W., Egri, P., Wittmann, G., Fekete, C., Gereben, B. & Bianco, A. C., okt. 2009, In : Molecular and cellular biology. 29, 19, p. 5339-5347 9 p.

Research output: Article

57 Citations (Scopus)

The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia

Fernandes, G. W., Bocco, B. M. L. C., Fonseca, T. L., McAninch, E. A., Jo, S., Lartey, L. J., O-Sullivan, I. S., Unterman, T. G., Preite, N. Z., Voigt, R. M., Forsyth, C. B., Keshavarzian, A., Sinkó, R., Goldfine, A. B., Patti, M. E., Ribeiro, M. O., Gereben, B. & Bianco, A. C., 2018, In : Cell Reports. 22, 2, p. 523-534 12 p.

Research output: Article

7 Citations (Scopus)

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Dentice, M., Bandyopadhyay, A., Gereben, B., Callebaut, I., Christoffolete, M. A., Kim, B. W., Nissim, S., Mornon, J. P., Zavacki, A. M., Zeöld, A., Capelo, L. P., Curcio-Morelli, C., Ribeiro, R., Harney, J. W., Tabin, C. J. & Bianco, A. C., júl. 2005, In : Nature Cell Biology. 7, 7, p. 698-705 8 p.

Research output: Article

160 Citations (Scopus)

The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1)

Gereben, B., Salvatore, D., Harney, J. W., Tu, H. M. & Larsen, P. R., jan. 1 2001, In : Molecular Endocrinology. 15, 1, p. 112-124 13 p.

Research output: Article

Open Access
55 Citations (Scopus)

The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure

Callebaut, I., Curcio-Morelli, C., Mornon, J. P., Gereben, B., Buettner, C., Huang, S., Castro, B., Fonseca, T. L., Harney, J. W., Larsen, P. R. & Bianco, A. C., szept. 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 36887-36896 10 p.

Research output: Article

99 Citations (Scopus)