• 4608 Citations
  • 35 h-Index
19952019

Research output per year

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Research Output

  • 4608 Citations
  • 35 h-Index
  • 62 Article
  • 7 Review article
  • 1 Comment/debate
  • 1 Editorial
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Article
1995
7 Citations (Scopus)
1998
9 Citations (Scopus)

Inverse hierarchy of vimentin epitope expression in primary cultures of chicken and rat astrocytes: A double-immunofluorescence study

Gereben, B., Leuhuber, K., Rausch, W. D., Galfi, P., Jancsik, V. & Rudas, P., dec. 1 1998, In : NEUROBIOLOGY. 6, 2, p. 141-150 10 p.

Research output: Article

4 Citations (Scopus)
1999

Cloning and expression of the chicken type 2 iodothyronine 5'- deiodinase

Gereben, B., Bartha, T., Tu, H. M., Harney, J. W., Rudas, P. & Larsen, P. R., máj. 14 1999, In : Journal of Biological Chemistry. 274, 20, p. 13768-13776 9 p.

Research output: Article

69 Citations (Scopus)
2000

Characterization of the 5′-flanking and 5′-untranslated regions of the cyclic adenosine 3′,5′-monophosphate-responsive human type 2 iodothyronine deiodinase gene

Bartha, T., Kim, S. W., Salvatore, D., Gereben, B., Tu, H. M., Harney, J. W., Rudas, P. & Reed Larsen, P., jan. 1 2000, In : Endocrinology. 141, 1, p. 229-237 9 p.

Research output: Article

94 Citations (Scopus)

Distinct subcellular localization of transiently expressed types 1 and 2 iodothyronine deiodinases as determined by immunofluorescence confocal microscopy

Baqui, M. M. A., Gereben, B., Harney, J. W., Larsen, P. R. & Bianco, A. C., jan. 1 2000, In : Endocrinology. 141, 11, p. 4309-4312 4 p.

Research output: Article

Open Access
96 Citations (Scopus)

Selective proteolysis of human type 2 deiodinase: A novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation

Gereben, B., Goncalves, C., Harney, J. W., Larsen, P. R. & Bianco, A. C., jan. 1 2000, In : Molecular Endocrinology. 14, 11, p. 1697-1708 12 p.

Research output: Article

Open Access
116 Citations (Scopus)
2001

Cloning and functional characterization of an uncoupling protein homolog in hummingbirds

Vianna, C. R., Hagen, T., Zhang, C. Y., Bachman, E., Boss, O., Gereben, B., Moriscot, A. S., Lowell, B. B., Bicudo, J. E. P. W. & Bianco, A. C., jún. 2001, In : Physiological Genomics. 2001, 5, p. 137-145 9 p.

Research output: Article

69 Citations (Scopus)

The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1)

Gereben, B., Salvatore, D., Harney, J. W., Tu, H. M. & Larsen, P. R., jan. 1 2001, In : Molecular Endocrinology. 15, 1, p. 112-124 13 p.

Research output: Article

Open Access
55 Citations (Scopus)

Transcriptional regulation of iodothyronine deiodinases during embryonic development

Van der Geyten, S., Segers, I., Gereben, B., Bartha, T., Rudas, P., Larsen, P. R., Kühn, E. R. & Darras, V. M., okt. 25 2001, In : Molecular and Cellular Endocrinology. 183, 1-2, p. 1-9 9 p.

Research output: Article

52 Citations (Scopus)
2002

The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression

Gereben, B., Kollár, A., Harney, J. W. & ReedLarsen, P., 2002, In : Molecular Endocrinology. 16, 7, p. 1667-1679 13 p.

Research output: Article

44 Citations (Scopus)

Ubc6p and Ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase

Botero, D., Gereben, B., Goncalves, C., De Jesus, L. A., Harney, J. W. & Bianco, A. C., szept. 2002, In : Molecular Endocrinology. 16, 9, p. 1999-2007 9 p.

Research output: Article

48 Citations (Scopus)
2003

Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation

Curcio-Morelli, C., Zavacki, A. M., Christofollete, M., Gereben, B., De Freitas, B. C. G., Harney, J. W., Li, Z., Wu, G. & Bianco, A. C., júl. 2003, In : Journal of Clinical Investigation. 112, 2, p. 189-196 8 p.

Research output: Article

101 Citations (Scopus)

Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes

Baqui, M., Botero, D., Gereben, B., Curcio, C., Harney, J. W., Salvatore, D., Sorimachi, K., Larsen, P. R. & Bianco, A. C., jan. 10 2003, In : Journal of Biological Chemistry. 278, 2, p. 1206-1211 6 p.

Research output: Article

95 Citations (Scopus)

In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases

Curcio-Morelli, C., Gereben, B., Zavacki, A. M., Kim, B. W., Huang, S., Harney, J. W., Larsen, P. R. & Bianco, A. C., márc. 1 2003, In : Endocrinology. 144, 3, p. 937-946 10 p.

Research output: Article

53 Citations (Scopus)

The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure

Callebaut, I., Curcio-Morelli, C., Mornon, J. P., Gereben, B., Buettner, C., Huang, S., Castro, B., Fonseca, T. L., Harney, J. W., Larsen, P. R. & Bianco, A. C., szept. 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 36887-36896 10 p.

Research output: Article

99 Citations (Scopus)
2004

Chronic cardiac-specific thyrotoxicosis increases myocardial β-adrenergic responsiveness

Carvalho-Bianco, S. D., Kim, B. W., Zhang, J. X., Harney, J. W., Ribeiro, R. S., Gereben, B., Bianco, A. C., Mende, U. & Larsen, P. R., júl. 1 2004, In : Molecular Endocrinology. 18, 7, p. 1840-1849 10 p.

Research output: Article

41 Citations (Scopus)

Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: Implications for the nonthyroidal illness syndrome

Fekete, C., Gereben, B., Doleschall, M., Harney, J. W., Dora, J. M., Bianco, A. C., Sarkar, S., Liposits, Z., Rand, W., Emerson, C., Kacskovics, I., Reed Larsen, P. & Lechan, R. M., ápr. 2004, In : Endocrinology. 145, 4, p. 1649-1655 7 p.

Research output: Article

140 Citations (Scopus)

Ontogenic redistribution of type 2 deiodinase messenger ribonucleic acid in the brain of chicken

Gereben, B., Pachucki, J., Kollár, A., Liposits, Z. & Fekete, C., aug. 2004, In : Endocrinology. 145, 8, p. 3619-3625 7 p.

Research output: Article

35 Citations (Scopus)
2005

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Dentice, M., Bandyopadhyay, A., Gereben, B., Callebaut, I., Christoffolete, M. A., Kim, B. W., Nissim, S., Mornon, J. P., Zavacki, A. M., Zeöld, A., Capelo, L. P., Curcio-Morelli, C., Ribeiro, R., Harney, J. W., Tabin, C. J. & Bianco, A. C., júl. 2005, In : Nature Cell Biology. 7, 7, p. 698-705 8 p.

Research output: Article

160 Citations (Scopus)
2006

Characterization of the nuclear factor-κB responsiveness of the human dio2 gene

Zeöld, A., Doleschall, M., Haffner, M. C., Capelo, L. P., Menyhért, J., Liposits, Z., Da Silva, W. S., Bianco, A. C., Kacskovics, I., Fekete, C. & Gereben, B., 2006, In : Endocrinology. 147, 9, p. 4419-4429 11 p.

Research output: Article

55 Citations (Scopus)

Metabolic instability of type 2 deiodinase is transferable to stable proteins independently of subcellular localization

Zeöld, A., Pormüller, L., Dentice, M., Harney, J. W., Curcio-Morelli, C., Tente, S. M., Bianco, A. C. & Gereben, B., okt. 20 2006, In : Journal of Biological Chemistry. 281, 42, p. 31538-31543 6 p.

Research output: Article

37 Citations (Scopus)
2007

Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain

Fekete, C., Freitas, B. C. G., Zeöld, A., Wittmann, G., Kádár, A., Liposits, Z., Christoffolete, M. A., Singru, P., Lechan, R. M., Bianco, A. C. & Gereben, B., okt. 1 2007, In : Endocrinology. 148, 10, p. 4865-4874 10 p.

Research output: Article

28 Citations (Scopus)

Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity

Sagar, G. D. V., Gereben, B., Callebaut, I., Mornon, J. P., Zeöld, A., Da Silva, W. S., Luongo, C., Dentice, M., Tente, S. M., Freitas, B. C. G., Harney, J. W., Zavacki, A. M. & Bianco, A. C., júl. 2007, In : Molecular and cellular biology. 27, 13, p. 4774-4783 10 p.

Research output: Article

71 Citations (Scopus)
2008
32 Citations (Scopus)

The thyroid hormone-inactivating deiodinase functions as a homodimer

Sagar, G. D. V., Gereben, B., Callebaut, I., Mornon, J. P., Zeöld, A., Curcio-Morelli, C., Harney, J. W., Luongo, C., Mulcahey, M. A., Larsen, P. R., Huang, S. A. & Bianco, A. C., jún. 2008, In : Molecular Endocrinology. 22, 6, p. 1382-1393 12 p.

Research output: Article

32 Citations (Scopus)
2009

Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells

Aerts, G., Drigo, R. A., Van Herck, S. L. J., Sammels, E., Mirebeau-Prunier, D., Gereben, B., Zeöld, A., Harney, J. W., Huang, S. A., Mulcahey, M. A., Van Der Geyten, S., Van Den Bergh, G., Arckens, L., Darras, V. M. & Zavacki, A. M., nov. 2009, In : Endocrinology. 150, 11, p. 5171-5180 10 p.

Research output: Article

2 Citations (Scopus)

The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase

Zavacki, A. M., E Drigo, R. A., Freitas, B. C. G., Chung, M., Harney, J. W., Egri, P., Wittmann, G., Fekete, C., Gereben, B. & Bianco, A. C., okt. 2009, In : Molecular and cellular biology. 29, 19, p. 5339-5347 9 p.

Research output: Article

57 Citations (Scopus)
2010

Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells

Freitas, B. C. G., Gereben, B., Castillo, M., Kalló, I., Zeöld, A., Egri, P., Liposits, Z., Zavacki, A. M., Maciel, R. M. B., Jo, S., Singru, P., Sanchez, E., Lechan, R. M. & Bianco, A. C., jún. 1 2010, In : Journal of Clinical Investigation. 120, 6, p. 2206-2217 12 p.

Research output: Article

102 Citations (Scopus)

Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway

Christoffolete, M. A., Doleschall, M., Egri, P., Liposits, Z., Zavacki, A. M., Bianco, A. C. & Gereben, B., máj. 2010, In : Journal of Endocrinology. 205, 2, p. 179-186 8 p.

Research output: Article

23 Citations (Scopus)
11 Citations (Scopus)
2011

Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eiF2a-mediated decrease in type 2 deiodinase synthesis

e Drigo, R. A., Fonseca, T. L., Castillo, M., Salathe, M., Simovic, G., Mohácsik, P., Gereben, B. & Bianco, A. C., dec. 2011, In : Molecular Endocrinology. 25, 12, p. 2065-2075 11 p.

Research output: Article

21 Citations (Scopus)

KISS1R intracellular trafficking and degradation: Effect of the Arg386Pro disease-associated mutation

Bianco, S. D. C., Vandepas, L., Correa-Medina, M., Gereben, B., Mukherjee, A., Kuohung, W., Carroll, R., Teles, M. G., Latronico, A. C. & Kaiser, U. B., ápr. 2011, In : Endocrinology. 152, 4, p. 1616-1626 11 p.

Research output: Article

38 Citations (Scopus)
2012

A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons

Kalló, I., Mohácsik, P., Vida, B., Zeöld, A., Bardóczi, Z., Zavacki, A. M., Farkas, E., Kádár, A., Hrabovszky, E., Arrojo e Drigo, R., Dong, L., Barna, L., Palkovits, M., Borsay, B. A., Herczeg, L., Lechan, R. M., Bianco, A. C., Liposits, Z., Fekete, C. & Gereben, B., jún. 18 2012, In : PloS one. 7, 6, e37860.

Research output: Article

32 Citations (Scopus)

Interleukin-6 Receptor α is Co-localised with Melanin-Concentrating Hormone in Human and Mouse Hypothalamus

Schéle, E., Fekete, C., Egri, P., Füzesi, T., Palkovits, M., Keller, É., Liposits, Z., Gereben, B., Karlsson-Lindahl, L., Shao, R. & Jansson, J. O., jún. 2012, In : Journal of Neuroendocrinology. 24, 6, p. 930-943 14 p.

Research output: Article

21 Citations (Scopus)

Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism

Jo, S., Kalló, I., Bardóczi, Z., e Drigo, R. A., Zeöld, A., Liposits, Z., Oliva, A., Lemmon, V. P., Bixby, J. L., Gereben, B. & Bianco, A. C., jún. 20 2012, In : Journal of Neuroscience. 32, 25, p. 8491-8500 10 p.

Research output: Article

44 Citations (Scopus)
2013

Coordination of hypothalamic and pituitary T3 production regulates TSH expression

Fonseca, T. L., Correa-Medina, M., Campos, M. P. O., Wittmann, G., Werneck-de-Castro, J. P., Drigo, R. A., Mora-Garzon, M., Ueta, C. B., Caicedo, A., Fekete, C., Gereben, B., Lechan, R. M. & Bianco, A. C., ápr. 1 2013, In : Journal of Clinical Investigation. 123, 4, p. 1492-1500 9 p.

Research output: Article

86 Citations (Scopus)

The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex

Arrojo e Drigo, R., Egri, P., Jo, S., Gereben, B. & Bianco, A. C., dec. 1 2013, In : Molecular Endocrinology. 27, 12, p. 2105-2115 11 p.

Research output: Article

14 Citations (Scopus)
2014

American thyroid association guide to investigating thyroid hormone economy and action in rodent and cell models

Bianco, A. C., Anderson, G., Forrest, D., Galton, V. A., Gereben, B., Kim, B. W., Kopp, P. A., Liao, X. H., Obregon, M. J., Peeters, R. P., Refetoff, S., Sharlin, D. S., Simonides, W. S., Weiss, R. E. & Williams, G. R., jan. 1 2014, In : Thyroid. 24, 1, p. 88-168 81 p.

Research output: Article

99 Citations (Scopus)
7 Citations (Scopus)

Tissue-specific inactivation of type 2 deiodinase reveals multilevel control of fatty acid oxidation by thyroid hormone in the mouse

Fonseca, T. L., Werneck-De-Castro, J. P., Castillo, M., Bocco, B. M. L. C., Fernandes, G. W., McAninch, E. A., Ignacio, D. L., Moises, C. C. S., Ferreira, A., Gereben, B. & Bianco, A. C., máj. 2014, In : Diabetes. 63, 5, p. 1594-1604 11 p.

Research output: Article

36 Citations (Scopus)
2015

Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine

De Castro, J. P. W., Fonseca, T. L., Ueta, C. B., McAninch, E. A., Abdalla, S., Wittmann, G., Lechan, R. M., Gereben, B. & Bianco, A. C., febr. 2 2015, In : Journal of Clinical Investigation. 125, 2, p. 769-781 13 p.

Research output: Article

69 Citations (Scopus)
16 Citations (Scopus)

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

Jansen, S. W., Akintola, A. A., Roelfsema, F., Van Der Spoel, E., Cobbaert, C. M., Ballieux, B. E., Egri, P., Kvarta-Papp, Z., Gereben, B., Fekete, C., Slagboom, P. E., Van Der Grond, J., Demeneix, B. A., Pijl, H., Westendorp, R. G. J. & Van Heemst, D., jún. 19 2015, In : Scientific reports. 5, 11525.

Research output: Article

37 Citations (Scopus)

Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents

Wittmann, G., Szabon, J., Mohácsik, P., Nouriel, S. S., Gereben, B., Fekete, C. & Lechan, R. M., ápr. 1 2015, In : Endocrinology. 156, 4, p. 1552-1564 13 p.

Research output: Article

16 Citations (Scopus)

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity

Fonseca, T. L., Fernandes, G. W., McAninch, E. A., Bocco, B. M. L. C., Abdalla, S. M., Ribeiro, M. O., Mohácsik, P., Fekete, C., Li, D., Xing, X., Wang, T., Gereben, B. & Bianco, A. C., nov. 10 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 45, p. 14018-14023 6 p.

Research output: Article

Open Access
13 Citations (Scopus)

Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes

McAninch, E. A., Jo, S., Preite, N. Z., Farkas, E., Mohácsik, P., Fekete, C., Egri, P., Gereben, B., Li, Y., Deng, Y., Patti, M. E., Zevenbergen, C., Peeters, R. P., Mash, D. C. & Bianco, A. C., márc. 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 3, p. 920-933 14 p.

Research output: Article

37 Citations (Scopus)

Thyroid hormone signaling in male mouse skeletal muscle is largely independent of D2 in myocytes

Werneck-De-Castro, J. P., Fonseca, T. L., Ignacio, D. L., Fernandes, G. W., Andrade-Feraud, C. M., Lartey, L. J., Ribeiro, M. B., Ribeiro, M. O., Gereben, B. & Bianco, A. C., okt. 1 2015, In : Endocrinology. 156, 10, p. 3842-3852 11 p.

Research output: Article

13 Citations (Scopus)
2016

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Yavari, A., Stocker, C. J., Ghaffari, S., Wargent, E. T., Steeples, V., Czibik, G., Pinter, K., Bellahcene, M., Woods, A., Martínez De Morentin, P. B., Cansell, C., Lam, B. Y. H., Chuster, A., Petkevicius, K., Nguyen-Tu, M. S., Martinez-Sanchez, A., Pullen, T. J., Oliver, P. L., Stockenhuber, A., Nguyen, C. & 34 others, Lazdam, M., O'Dowd, J. F., Harikumar, P., Tóth, M., Beall, C., Kyriakou, T., Parnis, J., Sarma, D., Katritsis, G., Wortmann, D. D. J., Harper, A. R., Brown, L. A., Willows, R., Gandra, S., Poncio, V., De Oliveira Figueiredo, M. J., Qi, N. R., Peirson, S. N., McCrimmon, R. J., Gereben, B., Tretter, L., Fekete, C., Redwood, C., Yeo, G. S. H., Heisler, L. K., Rutter, G. A., Smith, M. A., Withers, D. J., Carling, D., Sternick, E. B., Arch, J. R. S., Cawthorne, M. A., Watkins, H. & Ashrafian, H., máj. 10 2016, In : Cell Metabolism. 23, 5, p. 821-836 16 p.

Research output: Article

48 Citations (Scopus)