• 6667 Citations
  • 40 h-Index
19972019

Research output per year

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Research Output

  • 6667 Citations
  • 40 h-Index
  • 67 Article
  • 12 Review article
  • 2 Editorial
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Article
2019

Hematopoietic or osteoclast-specific deletion of Syk leads to increased bone mass in experimental mice

Csete, D., Simon, E., Alatshan, A., Aradi, P., Dobó-Nagy, C., Jakus, Z., Benko, S., Gyori, D. S. & Mócsai, A., jan. 1 2019, In : Frontiers in immunology. 10, APR, 937.

Research output: Article

Open Access
2 Citations (Scopus)
Open Access

TRPA1 ion channel determines beneficial and detrimental effects of GYY4137 in murine serum-transfer arthritis

Bátai, I. Z., Sár, C. P., Horváth, Á., Borbély, É., Bölcskei, K., Kemény, Á., Sándor, Z., Nemes, B., Helyes, Z., Perkecz, A., Mócsai, A., Pozsgai, G. & Pintér, E., jan. 1 2019, In : Frontiers in Pharmacology. 10, 964.

Research output: Article

Open Access
2018
8 Citations (Scopus)

Lineage-specific analysis of Syk function in autoantibody-induced arthritis

Németh, T., Futosi, K., Szilveszter, K., Vilinovszki, O., Kiss-Pápai, L. & Mócsai, A., márc. 19 2018, In : Frontiers in Immunology. 9, MAR, 555.

Research output: Article

5 Citations (Scopus)

Myeloid-specific deletion of Mcl-1 yields severely neutropenic mice that survive and breed in homozygous form

Csepregi, J. Z., Orosz, A., Zajta, E., Kasa, O., Nemeth, T., Simon, E., Fodor, S., Csonka, K., Baratki, B. L., Kovesdi, D., He, Y. W., Gacser, A. & Mocsai, A., dec. 15 2018, In : Journal of Immunology. 201, 12, p. 3793-3803 11 p.

Research output: Article

4 Citations (Scopus)

Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases

Wannick, M., Bezdek, S., Guillen, N., Thieme, M., Meshrkey, F., Mousavi, S., Seeling, M., Nimmerjahn, F., Mócsai, A., Zillikens, D., Sezin, T. & Sadik, C. D., dec. 1 2018, In : Pharmacology Research and Perspectives. 6, 6, e00438.

Research output: Article

2 Citations (Scopus)

The Yin and Yang of tyrosine kinase inhibition during experimental polymicrobial sepsis

Gonçalves-de-Albuquerque, C. F., Rohwedder, I., Silva, A. R., Ferreira, A. S., Kurz, A. R. M., Cougoule, C., Klapproth, S., Eggersmann, T., Silva, J. D., de Oliveira, G. P., Capelozzi, V. L., Schlesinger, G. G., Costa, E. R., Elias Estrela Marins, R. D. C., Mócsai, A., Maridonneau-Parini, I., Walzog, B., Rocco, P. R. M., Sperandio, M. & de Castro-Faria-Neto, H. C., ápr. 30 2018, In : Frontiers in immunology. 9, APR, 901.

Research output: Article

3 Citations (Scopus)
2017

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps

Kienhöfer, D., Hahn, J., Stoof, J., Csepregi, J. Z., Reinwald, C., Urbonaviciute, V., Johnsson, C., Maueröder, C., Podolska, M. J., Biermann, M. H., Leppkes, M., Harrer, T., Hultqvist, M., Olofsson, P., Munoz, L. E., Mócsai, A., Herrmann, M., Schett, G., Holmdahl, R. & Hoffmann, M. H., máj. 18 2017, In : JCI insight. 2, 10

Research output: Article

Open Access
42 Citations (Scopus)

Extracellular vesicles regulate the human osteoclastogenesis: divergent roles in discrete inflammatory arthropathies

Marton, N., Kovács, O. T., Baricza, E., Kittel, A., Győri, D., Mócsai, A., Meier, F. M. P., Goodyear, C. S., McInnes, I. B., Búzás, E. & Nagy, G., okt. 1 2017, In : Cellular and Molecular Life Sciences. 74, 19, p. 3599-3611 13 p.

Research output: Article

13 Citations (Scopus)
14 Citations (Scopus)
2016

Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

Németh, B., Doczi, J., Csete, D., Kacso, G., Ravasz, D., Adams, D., Kiss, G., Nagy, A. M., Horvath, G., Tretter, L., Mócsai, A., Csépányi-Kömi, R., Iordanov, I., Adam-Vizi, V. & Chinopoulos, C., jan. 1 2016, In : FASEB Journal. 30, 1, p. 286-300 15 p.

Research output: Article

50 Citations (Scopus)

Lack of Galanin 3 Receptor Aggravates Murine Autoimmune Arthritis

Botz, B., Kemény, Á., Brunner, S. M., Locker, F., Csepregi, J., Mócsai, A., Pintér, E., McDougall, J. J., Kofler, B. & Helyes, Z., jún. 1 2016, In : Journal of Molecular Neuroscience. 59, 2, p. 260-269 10 p.

Research output: Article

5 Citations (Scopus)
31 Citations (Scopus)

Nicotinic acetylcholine receptors modulate osteoclastogenesis

Mandl, P., Hayer, S., Karonitsch, T., Scholze, P., Gyori, D., Sykoutri, D., Blüml, S., Mócsai, A., Poór, G., Huck, S., Smolen, J. S. & Redlich, K., márc. 12 2016, In : Arthritis Research and Therapy. 18, 1, 63.

Research output: Article

11 Citations (Scopus)

Repercussion of megakaryocyte-specific Gata1 Loss on megakaryopoiesis and the hematopoietic precursor compartment

Meinders, M., Hoogenboezem, M., Scheenstra, M. R., De Cuyper, I. M., Papadopoulos, P., Németh, T., Mócsai, A., Van Den Berg, T. K., Kuijpers, T. W. & Gutiérrez, L., máj. 1 2016, In : PloS one. 11, 5, e0154342.

Research output: Article

5 Citations (Scopus)

Urine/plasma neutrophil gelatinase associated lipocalin ratio is a sensitive and specific marker of subclinical acute kidney injury in mice

Kaucsár, T., Godó, M., Révész, C., Kovács, M., Mócsai, A., Kiss, N., Albert, M., Krenács, T., Szénási, G. & Hamar, P., jan. 1 2016, In : PloS one. 11, 1, 0148043.

Research output: Article

16 Citations (Scopus)
2015
29 Citations (Scopus)

Erratum: Targeting vascular endothelial growth factor receptor 2 and protein kinase d1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro (PLoS ONE)

Varga, A., Gyulavári, P., Greff, Z., Futosi, K., Nemeth, T., Simon-Szabó, L., Kerekes, K., Szántai-Kis, C., Brauswetter, D., Kokas, M., Borbely, G., Erdei, A., Mócsai, A., Kéri, G. & Vántus, T., dec. 1 2015, In : PLoS One. 10, 12, e0144792.

Research output: Article

Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility

Medina, I., Cougoule, C., Drechsler, M., Bermudez, B., Koenen, R. R., Sluimer, J., Wolfs, I., Döring, Y., Herias, V., Gijbels, M., Bot, I., De Jager, S. C. A., Weber, C., Cleutjens, J., Van Berkel, T. J. C., Sikkink, K. J., Mócsai, A., Maridonneau-Parini, I., Soehnlein, O. & Biessen, E. A. L., aug. 11 2015, In : Circulation. 132, 6, p. 490-501 12 p.

Research output: Article

9 Citations (Scopus)

Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivity

Weber, F. C., Németh, T., Csepregi, J. Z., Dudeck, A., Roers, A., Ozsvári, B., Oswald, E., Puskás, L. G., Jakob, T., Mócsai, A. & Martin, S. F., jan. 1 2015, In : Journal of Experimental Medicine. 212, 1, p. 15-22 8 p.

Research output: Article

83 Citations (Scopus)

Targeting vascular endothelial growth factor receptor 2 and protein kinase D1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro

Varga, A., Gyulavári, P., Greff, Z., Futosi, K., Németh, T., Simon-Szabó, L., Kerekes, K., Szántai-Kis, C., Brauswetter, D., Kokas, M., Borbély, G., Erdei, A., Mócsai, A., Kéri, G. & Vántus, T., ápr. 14 2015, In : PloS one. 10, 4, e0124234.

Research output: Article

8 Citations (Scopus)

The Effects of Dasatinib in Experimental Acute Respiratory Distress Syndrome Depend on Dose and Etiology

Oliveira, G. P., Silva, J. D., Marques, P. S., Gonçalves-De-Albuquerque, C. F., Santos, H. L., Vascocellos, A. P., Takiya, C. M., Morales, M. M., Pelosi, P., Mócsai, A., De Castro-Faria-Neto, H. C. & Rocco, P. R. M., jan. 1 2015, In : Cellular Physiology and Biochemistry. 36, 4, p. 1644-1658 15 p.

Research output: Article

16 Citations (Scopus)
2014

Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model

Botz, B., Bölcskei, K., Kereskai, L., Kovács, M., Németh, T., Szigeti, K., Horváth, I., Máthé, D., Kovács, N., Hashimoto, H., Reglödi, D., Szolcsányi, J., Pintér, E., Mõcsai, A. & Helyes, Z., okt. 1 2014, In : Arthritis and Rheumatology. 66, 10, p. 2739-2750 12 p.

Research output: Article

30 Citations (Scopus)

MASP-1 induces a unique cytokine pattern in endothelial cells: A novel link between complement system and neutrophil granulocytes

Jani, P. K., Kajdácsi, E., Megyeri, M., Dobó, J., Doleschall, Z., Futosi, K., Tímár, C. I., Mócsai, A., Makó, V., Gál, P. & Cervenak, L., jan. 29 2014, In : PloS one. 9, 1, e87104.

Research output: Article

26 Citations (Scopus)

Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage

Schwab, L., Goroncy, L., Palaniyandi, S., Gautam, S., Triantafyllopoulou, A., Mocsai, A., Reichardt, W., Karlsson, F. J., Radhakrishnan, S. V., Hanke, K., Schmitt-Graeff, A., Freudenberg, M., Von Loewenich, F. D., Wolf, P., Leonhardt, F., Baxan, N., Pfeifer, D., Schmah, O., Schönle, A., Martin, S. F. & 9 others, Mertelsmann, R., Duyster, J., Finke, J., Prinz, M., Henneke, P., Häcker, H., Hildebrandt, G. C., Häcker, G. & Zeiser, R., jún. 2014, In : Nature medicine. 20, 6, p. 648-654 7 p.

Research output: Article

113 Citations (Scopus)

Research update for articles published in EJCI in 2012

Dullaart, R. P. F., Al-Daghri, N. M., Ashina, M., Bouzas-Mosquera, A., Brunetti, N. D., Buechler, C., Chen, H. S., Corrales, J. J., D'Archivio, M., Cas, A. D., Pino, G. G., Gómez-Abril, S. A., Gyori, D., Haslacher, H., Herder, C., Kerstens, M. N., Koutsilieris, M., Lombardi, C., Lupattelli, G., Mócsai, A. & 26 others, Msaouel, P., Orfao, A., Ormazabal, P., Pacher, R., Perkmann, T., Peteiro, J., Plischke, M., Reynaert, N. L., Ricci, M. A., Robles, N. R., Rocha, M., Rutten, E. P. A., Sabico, S., Santamaria, F., Santoro, F., Schmid, A., Schmidt, M., Schytz, H. W., Shyu, K. G., Tada, H., Thorand, B., Valerio, G., Vesely, D. L., Wu, T. E., Yamagishi, M. & Yeh, Y. T., okt. 1 2014, In : European Journal of Clinical Investigation. 44, 10, p. 1010-1023 14 p.

Research output: Article

1 Citation (Scopus)

The phosphoinositide 3-kinase isoform pi3kβ regulates osteoclast-mediated bone resorption in humans and mice

Györi, D., Csete, D., Benkö, S., Kulkarni, S., Mandl, P., Dobõ-Nagy, C., Vanhaesebroeck, B., Stephens, L., Hawkins, P. T. & Mõcsai, A., aug. 2014, In : Arthritis and Rheumatology. 66, 8, p. 2210-2221 12 p.

Research output: Article

14 Citations (Scopus)

The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment

Kova´cs, M., Ne´meth, T., Jakus, Z., Sitaru, C., Simon, E., Futosi, K., Botz, B., Helyes, Z., Lowell, C. A. & Mo´csai, A., jan. 1 2014, In : Journal of Experimental Medicine. 211, 10, p. 1993-2011 19 p.

Research output: Article

61 Citations (Scopus)

What is the future of targeted therapy in rheumatology: Biologics or small molecules?

Mócsai, A., Kovács, L. & Gergely, P., márc. 13 2014, In : BMC Medicine. 12, 1, 43.

Research output: Article

59 Citations (Scopus)
2013

Neutrophil cell surface receptors and their intracellular signal transduction pathways

Futosi, K., Fodor, S. & Mócsai, A., szept. 17 2013, In : International Immunopharmacology. 17, 3, p. 638-650 13 p.

Research output: Article

233 Citations (Scopus)

Phosphoinositide 3-OH kinase regulates integrin-dependent processes in neutrophils by signaling through its effector ARAP3

Gambardella, L., Anderson, K. E., Jakus, Z., Kovács, M., Voigt, S., Hawkins, P. T., Stephens, L., Mócsai, A. & Vermeren, S., jan. 1 2013, In : Journal of Immunology. 190, 1, p. 381-391 11 p.

Research output: Article

12 Citations (Scopus)

Reprint of Neutrophil cell surface receptors and their intracellular signal transduction pathways

Futosi, K., Fodor, S. & Mócsai, A., dec. 1 2013, In : International Immunopharmacology. 17, 4, p. 1185-1197 13 p.

Research output: Article

84 Citations (Scopus)
56 Citations (Scopus)

Tyrosine kinase inhibitors for the treatment of rheumatoid arthritis

Gomez-Puerta, J. A. & Mócsai, A., jún. 14 2013, In : Current topics in medicinal chemistry. 13, 6, p. 760-773 14 p.

Research output: Article

23 Citations (Scopus)
2012

Dasatinib inhibits proinflammatory functions of mature human neutrophils

Futosi, K., Németh, T., Pick, R., Vántus, T., Walzog, B. & Mócsai, A., máj. 24 2012, In : Blood. 119, 21, p. 4981-4991 11 p.

Research output: Article

55 Citations (Scopus)

Optimization of important early ADME(T) parameters of NADPH oxidase-4 inhibitor molecules

Borbély, G., Huszár, M., Varga, A., Futosi, K., Mócsai, A., Orfi, L., Idei, M., Mandl, J., Kéri, G. & Vántus, T., márc. 2012, In : Medicinal Chemistry. 8, 2, p. 174-181 8 p.

Research output: Article

3 Citations (Scopus)

Phospholipase Cγ2 is required for basal but not oestrogen deficiency-induced bone resorption

Kertész, Z., Gyori, D., Körmendi, S., Fekete, T., Kis-Tóth, K., Jakus, Z., Schett, G., Rajnavölgyi, É., Dobó-Nagy, C. & Mócsai, A., jan. 1 2012, In : European Journal of Clinical Investigation. 42, 1, p. 49-60 12 p.

Research output: Article

20 Citations (Scopus)

The role of neutrophils in autoimmune diseases

Németh, T. & Mócsai, A., márc. 30 2012, In : Immunology letters. 143, 1, p. 9-19 11 p.

Research output: Article

124 Citations (Scopus)
2011

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae

Boyle, K. B., Gyori, D., Sindrilaru, A., Scharffetter-Kochanek, K., Taylor, P. R., Mócsai, A., Stephens, L. R. & Hawkins, P. T., márc. 1 2011, In : Journal of Immunology. 186, 5, p. 2978-2989 12 p.

Research output: Article

46 Citations (Scopus)

PI3Kβ plays a critical role in neutrophil activation by immune complexes

Kulkarni, S., Sitaru, C., Jakus, Z., Anderson, K. E., Damoulakis, G., Davidson, K., Hirose, M., Juss, J., Oxley, D., Chessa, T. A. M., Ramadani, F., Guillou, H., Segonds-Pichon, A., Fritsch, A., Jarvis, G. E., Okkenhaug, K., Ludwig, R., Zillikens, D., Mocsai, A., Vanhaesebroeck, B. & 2 others, Stephens, L. R. & Hawkins, P. T., ápr. 12 2011, In : Science Signaling. 4, 168, ra23.

Research output: Article

99 Citations (Scopus)
2010

Genetic deficiency of Syk protects mice from autoantibody-induced arthritis

Jakus, Z., Simon, E., Balázs, B. & Mócsai, A., júl. 1 2010, In : Arthritis and rheumatism. 62, 7, p. 1899-1910 12 p.

Research output: Article

76 Citations (Scopus)

Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: Generation and analysis of a novel null mutation in mice

Németh, T., Futosi, K., Hably, C., Brouns, M. R., Jakob, S. M., Kovács, M., Kertész, Z., Walzog, B., Settleman, J. & Mócsai, A., szept. 1 2010, In : Journal of Immunology. 185, 5, p. 3064-3075 12 p.

Research output: Article

26 Citations (Scopus)
2009

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FclRγ-Syk- Card9-dependent innate immune activation

Werninghaus, K., Babiak, A., Groß, O., Hölscher, C., Dietrich, H., Agger, E. M., Mages, J., Mocsai, A., Schoenen, H., Finger, K., Nimmerjahn, F., Brown, G. D., Kirschning, C., Heit, A., Andersen, P., Wagner, H., Ruland, J. & Lang, R., jan. 16 2009, In : Journal of Experimental Medicine. 206, 1, p. 89-97 9 p.

Research output: Article

207 Citations (Scopus)

A fundamental role of mAbp1 in neutrophils: Impact on β2 integrin-mediated phagocytosis and adhesion in vivo

Schymeinsky, J., Gerstl, R., Mannigel, I., Niedung, K., Frommhold, D., Panthel, K., Heesemann, J., Sixt, M., Quast, T., Kolanus, W., Mocsai, A., Wienands, J., Sperandio, M. & Walzog, B., nov. 5 2009, In : Blood. 114, 19, p. 4209-4220 12 p.

Research output: Article

32 Citations (Scopus)
73 Citations (Scopus)

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

Gross, O., Poeck, H., Bscheider, M., Dostert, C., Hannesschläger, N., Endres, S., Hartmann, G., Tardivel, A., Schweighoffer, E., Tybulewicz, V., Mocsai, A., Tschopp, J. & Ruland, J., máj. 21 2009, In : Nature. 459, 7245, p. 433-436 4 p.

Research output: Article

578 Citations (Scopus)
2008
Open Access
42 Citations (Scopus)
2007

Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo

Frommhold, D., Mannigel, I., Schymeinsky, J., Mocsai, A., Poeschl, J., Walzog, B. & Sperandio, M., nov. 28 2007, In : BMC Immunology. 8, 31.

Research output: Article

46 Citations (Scopus)
2006

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

Mócsai, A., Abram, C. L., Jakus, Z., Hu, Y., Lanier, L. L. & Lowell, C. A., dec. 1 2006, In : Nature Immunology. 7, 12, p. 1326-1333 8 p.

Research output: Article

249 Citations (Scopus)