• 1073 Citations
  • 19 h-Index
19982019
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Research Output 1998 2019

  • 1073 Citations
  • 19 h-Index
  • 58 Article
  • 2 Conference contribution
  • 2 Review article
  • 1 Chapter
2019
1 Citation (Scopus)

Hypothalamic cell diversity: non-neuronal codes for long-distance volume transmission by neuropeptides

Alpár, A., Benevento, M., Romanov, R. A., Hökfelt, T. & Harkany, T., jún. 1 2019, In : Current Opinion in Neurobiology. 56, p. 16-23 8 p.

Research output: Review article

Ependyma
Neuropeptides
Ependymoglial Cells
Nerve Endings
Cerebrospinal Fluid

Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer’s disease

Zahola, P., Hanics, J., Pintér, A., Máté, Z., Gáspárdy, A., Hevesi, Z., Echevarria, D., Ádori, C., Barde, S., Törőcsik, B., Erdélyi, F., Szabó, G., Wagner, L., Kovacs, G. G., Hökfelt, T., Harkany, T. & Alpár, A., júl. 1 2019, In : Brain Structure and Function. 224, 6, p. 2061-2078 18 p.

Research output: Article

Brain Stem
Locus Coeruleus
Vertebrates
Alzheimer Disease
Norepinephrine

Unified Classification of Molecular, Network, and Endocrine Features of Hypothalamic Neurons

Romanov, R. A., Alpár, A., Hokfelt, T. & Harkany, T., jan. 1 2019, In : Annual Review of Neuroscience. 42, p. 1-26 26 p.

Research output: Review article

Neurons
Hypothalamus
gamma-Aminobutyric Acid
Glutamic Acid
Dopamine
2018
3 Citations (Scopus)

Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain

Király, K., Kozsurek, M., Lukácsi, E., Barta, B., Alpár, A., Balázsa, T., Fekete, C., Szabon, J., Helyes, Z., Bölcskei, K., Tékus, V., Tóth, Z., Pap, K., Gerber, G. & Puskár, Z., dec. 1 2018, In : Scientific Reports. 8, 1, 3490.

Research output: Article

Dipeptidyl Peptidase 4
Hyperalgesia
Neuroglia
Opioid Analgesics
Dipeptidyl-Peptidase IV Inhibitors
1 Citation (Scopus)
Hypothalamus
Dissection
Instinct
Neurophysiology
Metabolic Diseases
2017
2 Citations (Scopus)

Insulin-like growth factor I and its binding protein-3 are regulators of lactation and maternal responsiveness

Lékó, A. H., Cservenák, M., Szabó, É. R., Hanics, J., Alpár, A. & Dobolyi, A., dec. 1 2017, In : Scientific Reports. 7, 1, 3396.

Research output: Article

Insulin-Like Growth Factor I
Lactation
Insulin-Like Growth Factor Binding Protein 3
Carrier Proteins
Mothers
13 Citations (Scopus)

Molecular diversity of corticotropin-releasing hormone mRNA-containing neurons in the hypothalamus

Romanov, R. A., Alpár, A., Hokfelt, T. & Harkany, T., 2017, In : Journal of Endocrinology. 232, 3, p. R161-R172

Research output: Article

Corticotropin-Releasing Hormone
Hypothalamus
Neurons
Messenger RNA
Paraventricular Hypothalamic Nucleus
7 Citations (Scopus)

Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration

Hanics, J., Szodorai, E., Tortoriello, G., Malenczyk, K., Keimpema, E., Lubec, G., Hevesi, Z., Lutz, M. I., Kozsurek, M., Puskár, Z., Tóth, Z. E., Wagner, L., Kovács, G. G., Hökfelt, T. G. M., Harkany, T. & Alpár, A., márc. 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 10, p. E2006-E2015

Research output: Article

Metalloproteases
Neurons
Olfactory Bulb
Annexin A5
Neuroglia
2016
1 Citation (Scopus)

A novel form of compensation in the Tg2576 amyloid mouse model of alzheimer’s disease

Somogyi, A., Katonai, Z., Alpár, A. & Wolf, E., jún. 16 2016, In : Frontiers in Cellular Neuroscience. 10, JUN, 152.

Research output: Article

Amyloid
Alzheimer Disease
Neurons
Membranes
Aptitude
15 Citations (Scopus)

Tau phosphorylation-associated spine regression does not impair hippocampal-dependent memory in hibernating golden hamsters

Bullmann, T., Seeger, G., Stieler, J., Hanics, J., Reimann, K., Kretzschmann, T. P., Hilbrich, I., Holzer, M., Alpár, A. & Arendt, T., márc. 1 2016, In : Hippocampus. 26, 3, p. 301-318 18 p.

Research output: Article

Mesocricetus
Dendrites
Hibernation
Spine
Phosphorylation
2015
31 Citations (Scopus)

A secretagogin locus of the mammalian hypothalamus controls stress hormone release

Romanov, R. A., Alpár, A., Zhang, M. D., Zeisel, A., Calas, A., Landry, M., Fuszard, M., Shirran, S. L., Schnell, R., Dobolyi, A., Oláh, M., Spence, L., Mulder, J., Martens, H., Palkóvits, M., Uhlen, M., Sitte, H. H., Botting, C. H., Wagner, L., Linnarsson, S. & 2 others, Hökfelt, T. & Harkany, T., jan. 2 2015, In : EMBO Journal. 34, 1, p. 36-54 19 p.

Research output: Article

Corticotropin-Releasing Hormone
Hypothalamus
Neurons
Hormones
Paraventricular Hypothalamic Nucleus
22 Citations (Scopus)
Ice Cover
Cannabis
Cannabinoid Receptors
Endocannabinoids
Brain
11 Citations (Scopus)

Cannabinoid receptor-interacting protein Crip1a modulates CB1 receptor signaling in mouse hippocampus

Guggenhuber, S., Alpár, A., Chen, R., Schmitz, N., Wickert, M., Mattheus, T., Harasta, A. E., Purrio, M., Kaiser, N., Elphick, M. R., Monory, K., Kilb, W., Luhmann, H. J., Harkany, T., Lutz, B. & Klugmann, M., márc. 15 2015, (Accepted/In press) In : Brain Structure and Function.

Research output: Article

Receptor-Interacting Protein Serine-Threonine Kinases
Cannabinoid Receptor CB1
Cannabinoid Receptors
Hippocampus
Cannabinoids
2014
20 Citations (Scopus)

Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling

Alpár, A., Tortoriello, G., Calvigioni, D., Niphakis, M. J., Milenkovic, I., Bakker, J., Cameron, G. A., Hanics, J., Morris, C. V., Fuzik, J., Kovacs, G. G., Cravatt, B. F., Parnavelas, J. G., Andrews, W. D., Hurd, Y. L., Keimpema, E. & Harkany, T., júl. 17 2014, In : Nature Communications. 5, 4421.

Research output: Article

Endocannabinoids
axons
Growth
brain
Brain
4 Citations (Scopus)

Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents

Bitencourt, R. M., Alpár, A., Cinquina, V., Ferreira, S. G., Pinheiro, B. S., Lemos, C., Ledent, C., Takahashi, R. N., Sialana, F. J., Lubec, G., Cunha, R. A., Harkany, T. & Köfalvi, A., okt. 11 2014, In : Neurochemistry International. 90, p. 72-84 13 p.

Research output: Article

Cannabinoid Receptor CB1
Frontal Lobe
gamma-Aminobutyric Acid
Glucocorticoids
Rodentia
69 Citations (Scopus)

Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway

Tortoriello, G., Morris, C. V., Alpár, A., Fuzik, J., Shirran, S. L., Calvigioni, D., Keimpema, E., Botting, C. H., Reinecke, K., Herdegen, T., Courtney, M., Hurd, Y. L. & Harkany, T., ápr. 1 2014, In : EMBO Journal. 33, 7, p. 668-685 18 p.

Research output: Article

Stathmin
Superior Cervical Ganglion
Dronabinol
Cannabis
Brain
8 Citations (Scopus)

Revival of calcium-binding proteins for neuromorphology: Secretagogin typifies distinct cell populations in the avian brain

Gáti, G., Lendvai, D., Hökfelt, T., Harkany, T. & Alpár, A., 2014, In : Brain, Behavior and Evolution. 83, 2, p. 82-92 11 p.

Research output: Article

Calcium-Binding Proteins
Carrier Proteins
Brain
Population
Olfactory Bulb
2013
13 Citations (Scopus)

Diacylglycerol lipase a manipulation reveals developmental roles for intercellular endocannabinoid signaling

Keimpema, E., Alpár, A., Howell, F., Malenczyk, K., Hobbs, C., Hurd, Y. L., Watanabe, M., Sakimura, K., Kano, M., Doherty, P. & Harkany, T., jún. 28 2013, In : Scientific Reports. 3, 2093.

Research output: Article

Endocannabinoids
Lipoprotein Lipase
Cannabinoid Receptor CB1
Cholinergic Agents
Growth Cones
35 Citations (Scopus)

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

Zilberter, M., Ivanov, A., Ziyatdinova, S., Mukhtarov, M., Malkov, A., Alpár, A., Tortoriello, G., Botting, C. H., Fülöp, L., Osypov, A. A., Pitkänen, A., Tanila, H., Harkany, T. & Zilberter, Y., ápr. 2013, In : Journal of Neurochemistry. 125, 1, p. 157-171 15 p.

Research output: Article

Alzheimer Disease
Energy Metabolism
Transgenic Mice
Nutrition
Diet
29 Citations (Scopus)

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons

Keimpema, E., Tortoriello, G., Alpár, A., Capsoni, S., Arisi, I., Calvigioni, D., Hu, S. S. J., Cattaneo, A., Doherty, P., Mackie, K. & Harkany, T., jan. 29 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 5, p. 1935-1940 6 p.

Research output: Article

Monoacylglycerol Lipases
Endocannabinoids
Cholinergic Neurons
Nerve Growth Factor
Neurites
40 Citations (Scopus)

Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease

Lendvai, D., Morawski, M., Négyessy, L., Gáti, G., Jäger, C., Baksa, G., Glasz, T., Attems, J., Tanila, H., Arendt, T., Harkany, T. & Alpár, A., febr. 2013, In : Acta Neuropathologica. 125, 2, p. 215-229 15 p.

Research output: Article

Synapses
Hippocampus
Alzheimer Disease
Brevican
Chondroitin Sulfate Proteoglycans
5 Citations (Scopus)
Endocannabinoids
Synaptic Transmission
Obesity
Neurons
27 Citations (Scopus)

Perineuronal and perisynaptic extracellular matrix in the human spinal cord

Jäger, C., Lendvai, D., Seeger, G., Brückner, G., Matthews, R. T., Arendt, T., Alpár, A. & Morawski, M., máj. 5 2013, In : Neuroscience. 238, p. 168-184 17 p.

Research output: Article

Brevican
Extracellular Matrix
Spinal Cord
Aggrecans
Proteoglycans
2012
18 Citations (Scopus)

Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation

Attems, J., Alpár, A., Spence, L., McParland, S., Heikenwalder, M., Uhlén, M., Tanila, H., Hökfelt, T. G. M. & Harkany, T., ápr. 17 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6259-6264 6 p.

Research output: Article

Olfactory Bulb
Neurons
Calbindin 2
Neural Cell Adhesion Molecules
Tubulin
26 Citations (Scopus)

Cracking down on inhibition: Selective removal of GABAergic interneurons from hippocampal networks

Antonucci, F., Alpár, A., Kacza, J., Caleo, M., Verderio, C., Giani, A., Martens, H., Chaudhry, F. A., Allegra, M., Grosche, J., Michalski, D., Erck, C., Hoffmann, A., Harkany, T., Matteoli, M. & Härtig, W., febr. 8 2012, In : Journal of Neuroscience. 32, 6, p. 1989-2001 13 p.

Research output: Article

Interneurons
Antibodies
Amino Acid Transport System A
Hippocampus
Vesicular Glutamate Transport Protein 1
17 Citations (Scopus)

Perisynaptic aggrecan-based extracellular matrix coats in the human lateral geniculate body devoid of perineuronal nets

Lendvai, D., Morawski, M., Brückner, G., Négyessy, L., Baksa, G., Glasz, T., Patonay, L., Matthews, R. T., Arendt, T. & Alpár, A., febr. 2012, In : Journal of Neuroscience Research. 90, 2, p. 376-387 12 p.

Research output: Article

Geniculate Bodies
Aggrecans
Extracellular Matrix
Proteoglycans
Sulfates
37 Citations (Scopus)

The renaissance of Ca 2+-binding proteins in the nervous system: Secretagogin takes center stage

Alpár, A., Attems, J., Mulder, J., Hökfelt, T. & Harkany, T., febr. 2012, In : Cellular Signalling. 24, 2, p. 378-387 10 p.

Research output: Article

Nervous System
EF Hand Motifs
Neurons
Neurotransmitter Agents
Central Nervous System
2011
1 Citation (Scopus)

Activity-induced dendrite and dendritic spine development in human amyloid precursor protein transgenic mice

Alpár, A., Ueberham, U., Lendvai, D., Naumann, N., Rohn, S., Gáti, G., Arendt, T. & Gärtner, U., ápr. 2011, In : International Journal of Developmental Neuroscience. 29, 2, p. 107-114 8 p.

Research output: Article

Dendritic Spines
Amyloid beta-Protein Precursor
Human Development
Dendrites
Transgenic Mice
84 Citations (Scopus)

Molecular reorganization of endocannabinoid signalling in Alzheimer's disease

Mulder, J., Zilberter, M., Pasquaré, S. J., Alpár, A., Schulte, G., Ferreira, S. G., Köfalvi, A., Martín-Moreno, A. M., Keimpema, E., Tanila, H., Watanabe, M., MacKie, K., Hortobágyi, T., De Ceballos, M. L. & Harkany, T., ápr. 2011, In : Brain. 134, 4, p. 1041-1060 20 p.

Research output: Article

Endocannabinoids
Monoacylglycerol Lipases
Cannabinoid Receptor CB1
Hydrolases
Alzheimer Disease
2010
13 Citations (Scopus)

Chondroitin sulphate proteoglycan-based perineuronal net establishment is largely activity-independent in chick visual system

Gáti, G., Morawski, M., Lendvai, D., Matthews, R. T., Jäger, C., Zachar, G., Arendt, T. & Alpár, A., nov. 2010, In : Journal of Chemical Neuroanatomy. 40, 3, p. 243-247 5 p.

Research output: Article

Chondroitin Sulfate Proteoglycans
Extracellular Matrix
Light
Telencephalon
Birds

Cluster analysis of cortical pyramidal neurons using SOM

Schierwagen, A., Villmann, T., Alpár, A. & Gärtner, U., 2010, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 5998 LNAI. p. 120-130 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 5998 LNAI).

Research output: Conference contribution

Transgenic Mice
Cluster analysis
Cluster Analysis
Cortex
Neurons
14 Citations (Scopus)

Distribution and classification of aggrecan-based extracellular matrix in the thalamus of the rat

Gáti, G., Morawski, M., Lendvai, D., Jäger, C., Négyessy, L., Arendt, T. & Alpár, A., nov. 15 2010, In : Journal of Neuroscience Research. 88, 15, p. 3257-3266 10 p.

Research output: Article

Aggrecans
Thalamus
Extracellular Matrix
Neocortex
Extracellular Space
18 Citations (Scopus)

Slow age-dependent decline of doublecortin expression and BrdU labeling in the forebrain from lesser hedgehog tenrecs

Alpár, A., Künzle, H., Gärtner, U., Popfeoua, Y., Bauer, U., Grosche, J., Reichenbach, A. & Härtig, W., máj. 12 2010, In : Brain Research. 1330, p. 9-19 11 p.

Research output: Article

Insectivora
Deoxyuridine
Prosencephalon
Olfactory Bulb
Neurons
19 Citations (Scopus)

Transgenic expression of human wild-type amyloid precursor protein decreases neurogenesis in the adult hippocampus

Naumann, N., Alpár, A., Ueberham, U., Arendt, T. & Gärtner, U., aug. 2010, In : Hippocampus. 20, 8, p. 971-979 9 p.

Research output: Article

Amyloid beta-Protein Precursor
Neurogenesis
Hippocampus
Neuronal Plasticity
Survival
2009
20 Citations (Scopus)

Chondroitin sulfate proteoglycan-based extracellular matrix in chicken (Gallus domesticus) brain

Morawski, M., Alpár, A., Brückner, G., Fiedler, A., Jäger, C., Gati, G., Stieler, J. T. & Arendt, T., jún. 12 2009, In : Brain Research. 1275, p. 10-23 14 p.

Research output: Article

Chondroitin Sulfate Proteoglycans
Extracellular Matrix
Chickens
Neurons
Brain
1 Citation (Scopus)
Neuronal Plasticity
Neurons
Dendritic Spines
Monomeric GTP-Binding Proteins
Pyramidal Cells
6 Citations (Scopus)
Amyloid beta-Protein Precursor
Neuronal Plasticity
Neurons
Brain
2008
5 Citations (Scopus)
Neurons
Vibrissae
Pyramidal Cells
ras Proteins
Monomeric GTP-Binding Proteins
2 Citations (Scopus)

Neuromorphological phenotyping in transgenic mice: A multiscale fractal analysis

Schierwagen, A., Costa, L. D. F., Alpar, A., Gärtner, U. & Arendt, T., jan. 1 2008, Modeling and Simulation in Science, Engineering and Technology. 9780817645557 ed. Springer Basel, p. 185-192 8 p. (Modeling and Simulation in Science, Engineering and Technology; no. 9780817645557).

Research output: Chapter

Transgenic Mice
Fractal Analysis
Multiscale Analysis
Fractals
Neurons
2007
2 Citations (Scopus)

Effects of wild-type and mutant human amyloid precursor protein on cortical afferent network

Alpár, A., Ueberham, U., Seeger, G., Arendt, T. & Gärtner, U., aug. 2007, In : NeuroReport. 18, 12, p. 1247-1250 4 p.

Research output: Article

Amyloid beta-Protein Precursor
Pyramidal Cells
Transgenic Mice
Amyloid
Cholinergic Agents
2 Citations (Scopus)

Multiscale fractal analysis of cortical pyramidal neurons

Schierwagen, A., Da Fontoura Costa, L., Alpár, A. & Gärtner, U., 2007, Informatik aktuell. p. 424-428 5 p.

Research output: Conference contribution

Fractal Analysis
Multiscale Analysis
Fractal dimension
Fractal Dimension
Fractals
4 Citations (Scopus)

Scaling properties of pyramidal neurons in mice neocortex

Schierwagen, A., Alpár, A. & Gärtner, U., jún. 2007, In : Mathematical Biosciences. 207, 2, p. 352-364 13 p.

Research output: Article

neocortex
Pyramidal Cells
Neocortex
Neurons
Mouse
2006
24 Citations (Scopus)

Development and surgical anatomy of the round window niche

Tóth, M., Alpár, A., Patonay, L. & Oláh, I., 2006, In : Annals of Anatomy. 188, 2, p. 93-101 9 p.

Research output: Article

Osteogenesis
Anatomy
niches
bone formation
Exostoses
46 Citations (Scopus)

Different dendrite and dendritic spine alterations in basal and apical arbors in mutant human amyloid precursor protein transgenic mice

Alpár, A., Ueberham, U., Brückner, M. K., Seeger, G., Arendt, T. & Gärtner, U., júl. 12 2006, In : Brain Research. 1099, 1, p. 189-198 10 p.

Research output: Article

Dendritic Spines
Amyloid beta-Protein Precursor
Amyloid Plaques
Dendrites
Transgenic Mice
54 Citations (Scopus)

Distribution of pyramidal cells associated with perineuronal nets in the neocortex of rat

Alpár, A., Gärtner, U., Härtig, W. & Brückner, G., nov. 20 2006, In : Brain Research. 1120, 1, p. 13-22 10 p.

Research output: Article

Pyramidal Cells
Neocortex
Neurons
Interneurons
Somatosensory Cortex
6 Citations (Scopus)

Surgical anatomy of the cochlea for cochlear implantation

Tóth, M., Alpár, A., Bodon, G., Moser, G. & Patonay, L., júl. 3 2006, In : Annals of Anatomy. 188, 4, p. 363-370 8 p.

Research output: Article

Tympanis
Cochlear Implantation
Cochlea
laminae (animals)
acoustics
17 Citations (Scopus)
Amyloid beta-Protein Precursor
Pyramidal Cells
Transgenic Mice
Phenotype
Dendrites
6 Citations (Scopus)

Topographical organisation of projections from the nucleus isthmi magnocellularis to the optic tectum of the chick brain

Tömböl, T., Alpár, A., Eyre, M. D. & Németh, A., márc. 2006, In : Anatomy and Embryology. 211, 2, p. 119-128 10 p.

Research output: Article

Superior Colliculi
Neurons
Brain
Injections
Axons
2005
5 Citations (Scopus)

Active percolation analysis of pyramidal neurons of somatosensory cortex: A comparison of wild type and p21H-RasVal12 transgenic mice

Costa, L. D. A. F., Barbosa, M. S., Schierwagen, A., Alpár, A., Gärtner, U. & Arendt, T., ápr. 2005, In : International Journal of Modern Physics C. 16, 4, p. 655-667 13 p.

Research output: Article

Transgenic Mice
cortexes
Cortex
neurons
Dispersions