Országos Onkológiai Intézet

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Article
2020

Absolute improvements in freedom from distant recurrence to tailor adjuvant endocrine therapies for premenopausal women: Results from TExT and Soft

Pagani, O., Francis, P. A., Fleming, G. F., Walley, B. A., Viale, G., Colleoni, M., Láng, I., Gómez, H. L., Tondini, C., Pinotti, G., Di Leo, A., Coates, A. S., Goldhirsch, A., Gelber, R. D. & Regan, M. M., ápr. 20 2020, In : Journal of Clinical Oncology. 38, 12, p. 1293-1303 11 p.

Research output: Article

Open Access
7 Citations (Scopus)
Open Access
3 Citations (Scopus)

Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab

Balatoni, T., Ladányi, A., Fröhlich, G., Czirbesz, K., Kovács, P., Pánczél, G., Bence, E., Plótár, V. & Liszkay, G., jan. 1 2020, In : Pathology and Oncology Research. 26, 1, p. 317-325 9 p.

Research output: Article

8 Citations (Scopus)

Implementation of Stereotactic Accelerated Partial Breast Irradiation Using Cyber-Knife – Technical Considerations and Early Experiences of a Phase II Clinical Study

Mészáros, N., Smanykó, V., Major, T., Stelczer, G., Jánváry, L., Kovács, E., Mária, B., Zaka, Z., Pukancsik, D., Takácsi, N. Z. & Polgár, C., jan. 1 2020, (Accepted/In press) In : Pathology and Oncology Research.

Research output: Article

Open Access

Long-term cardiac outcomes of patients with HER2-positive breast cancer treated in the adjuvant lapatinib and/or trastuzumab Treatment Optimization Trial

Eiger, D., Pondé, N. F., Agbor-Tarh, D., Moreno-Aspitia, A., Piccart, M., Hilbers, F. S., Werner, O., Chumsri, S., Dueck, A., Kroep, J. R., Gomez, H., Láng, I., Rodeheffer, R. J., Ewer, M. S., Suter, T. & de Azambuja, E., máj. 12 2020, In : British journal of cancer. 122, 10, p. 1453-1460 8 p.

Research output: Article

Normal tissue sparing using different techniques for prostate irradiation

Melles-Bencsik, B., Pócza, T., Major, T., Ágoston, P., Jorgo, K., Polgár, C. & Pesznyák, C., jan. 1 2020, In : Reports of Practical Oncology and Radiotherapy. 25, 1, p. 85-90 6 p.

Research output: Article

Selective Inhibition of HIF1α Expression by ZnSO4 Has Antitumoral Effects in Human Melanoma

Burián, Z., Ladányi, A., Barbai, T., Piurkó, V., Garay, T., Rásó, E. & Tímár, J., ápr. 1 2020, In : Pathology and Oncology Research. 26, 2, p. 673-679 7 p.

Research output: Article

1 Citation (Scopus)
2019

Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non- BRCA1/2 breast cancer families

Lakeman, I. M. M., Hilbers, F. S., Rodríguez-Girondo, M., Lee, A., Vreeswijk, M. P. G., Hollestelle, A., Seynaeve, C., Meijers-Heijboer, H., Oosterwijk, J. C., Hoogerbrugge, N., Oláh, E., Vasen, H. F. A., Van Asperen, C. J. & Devilee, P., jan. 1 2019, In : Journal of medical genetics.

Research output: Article

4 Citations (Scopus)

Adjuvant Anti-HER2 Therapy, treatment-related amenorrhea, and survival in premenopausal HER2-positive early breast cancer patients

Lambertini, M., Campbell, C., Bines, J., Korde, L. A., Izquierdo, M., Fumagalli, D., Del Mastro, L., Ignatiadis, M., Pritchard, K., Wolff, A. C., Jackisch, C., Lang, I., Untch, M., Smith, I., Boyle, F., Xu, B., Barrios, C. H., Baselga, J., Moreno-Aspitia, A., Piccart, M. & 2 others, Gelber, R. D. & De Azambuja, E., jan. 1 2019, In : Journal of the National Cancer Institute. 111, 1, djy094.

Research output: Article

18 Citations (Scopus)
1 Citation (Scopus)

A magyar sugárterápia jelenlegi helyzetének bemutatása

Major, T., Király, R. & Polgár, C., jún. 21 2019, In : Magyar onkologia. 64, 2, p. 93-101 9 p.

Research output: Article

Analysis of microRNA expression in brush cytology specimens improves the diagnosis of pancreatobiliary cancer

Le, N., Fillinger, J., Szanyi, S., Wichmann, B., Nagy, Z. B., Ivády, G., Burai, M., Tarpay, Pozsár, J., Pap, Molnár, B., Csuka, O., Bak, M., Tulassay, Z. & Szmola, R., szept. 2019, In : Pancreatology. 19, 6, p. 873-879 7 p.

Research output: Article

2 Citations (Scopus)

Assessment of the Role of Everolimus Therapy in Patients with Renal Cell Carcinoma Based on Daily Routine and Recent Research Results

Maráz, A., Csejtei, A., Kocsis, J., Szűcs, M., Kahán, Z., Bodoky, G., Dank, M., Mangel, L., Révész, J., Varga, Z. & Géczi, L., jan. 15 2019, In : Pathology and Oncology Research. 25, 1, p. 149-156 8 p.

Research output: Article

2 Citations (Scopus)

Assessment of the Safety of Glucocorticoid Regimens in Combination with Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer: A Randomized, Open-label Phase 2 Study

Attard, G., Merseburger, A. S., Arlt, W., Sternberg, C. N., Feyerabend, S., Berruti, A., Joniau, S., Géczi, L., Lefresne, F., Lahaye, M., Shelby, F. N., Pissart, G., Chua, S., Jones, R. J. & Tombal, B., aug. 2019, In : JAMA Oncology. 5, 8, p. 1159-1167 9 p.

Research output: Article

8 Citations (Scopus)

Az axilláris nyirokcsomók dózisa különféle besugárzási mezõelrendezésekbõl emlõmegtartó mûtét után

Bukovszky, B., Fodor, J., Zongor, Z., Mihály, D., Mátrai, Z., Polgár, C. & Major, T., jún. 21 2019, In : Magyar onkologia. 64, 2, p. 103-110 8 p.

Research output: Article

Az immunellenőrzőpont-gátlók okozta mellékhatások és kezelésük

Tamás, D., Orsolya, H. & Lajos, G., jan. 1 2019, In : Magyar onkologia. 63, 3, p. 246-255 10 p.

Research output: Article

Open Access
1 Citation (Scopus)

Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases

Baska, F., Sipos, A., Őrfi, Z., Nemes, Z., Dobos, J., Szántai-Kis, C., Szabó, E., Szénási, G., Dézsi, L., Hamar, P., Cserepes, M. T., Tóvári, J., Garamvölgyi, R., Krekó, M. & Őrfi, L., dec. 15 2019, In : European Journal of Medicinal Chemistry. 184, 111710.

Research output: Article

1 Citation (Scopus)

DNA profiling of Hungarian King Béla III and other skeletal remains originating from the Royal Basilica of Székesfehérvár

Olasz, J., Seidenberg, V., Hummel, S., Szentirmay, Z., Szabados, G., Melegh, B. & Kásler, M., ápr. 5 2019, In : Archaeological and Anthropological Sciences. 11, 4, p. 1345-1357 13 p.

Research output: Article

3 Citations (Scopus)
Open Access

Durvalumab for recurrent or metastatic head and neck squamous cell carcinoma: Results from a single-arm, phase II study in patients with ≥25% tumour cell PD-L1 expression who have progressed on platinum-based chemotherapy

Zandberg, D. P., Algazi, A. P., Jimeno, A., Good, J. S., Fayette, J., Bouganim, N., Ready, N. E., Clement, P. M., Even, C., Jang, R. W., Wong, S., Keilholz, U., Gilbert, J., Fenton, M., Braña, I., Henry, S., Remenar, E., Papai, Z., Siu, L. L., Jarkowski, A. & 5 others, Armstrong, J. M., Asubonteng, K., Fan, J., Melillo, G. & Mesía, R., jan. 2019, In : European Journal of Cancer. 107, p. 142-152 11 p.

Research output: Article

32 Citations (Scopus)

Emlőrák miatti szervmegtartó műtétek reszekciós széleinek vizsgálata. Multicentrikus retrospektív elemzés

Fakan, B., Baranyi, E., Horváth, R., Kálmán, E., Kulka, J., Tölgyesi, K., Török, M., Udvarhelyi, N., Zombori, T. & Cserni, G., jún. 1 2019, In : Orvosi hetilap. 160, 26, p. 1036-1044 9 p.

Research output: Article

ERG expression can predict the outcome of docetaxel combinedwith androgen deprivation therapy in metastatic hormone-sensitiveprostate cancer

Küronya, Z., Sükösd, F., Varga, L., Bíró, K., Gyergyay, F., Géczi, L., Nagyiványi, K., Jorgo, K., Szarvas, T., Kovács, Á., Laczó, I., Varga, Z., Pósfai, B., Pepó, J. & Maráz, A., jan. 1 2019, (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Article

1 Citation (Scopus)
2 Citations (Scopus)

Final analysis of the prevention of early menopause study (POEMS)/SWOG intergroup S0230

Moore, H. C. F., Unger, J. M., Phillips, K. A., Boyle, F., Hitre, E., Moseley, A., Porter, D. J., Francis, P. A., Goldstein, L. J., Gomez, H. L., Vallejos, C. S., Partridge, A. H., Dakhil, S. R., Garcia, A. A., Gralow, J. R., Lombard, J. M., Forbes, J. F., Martino, S., Barlow, W. E., Fabian, C. J. & 5 others, Minasian, L. M., Meyskens, F. L., Gelber, R. D., Hortobagyi, G. N. & Albain, K. S., jan. 1 2019, In : Journal of the National Cancer Institute. 111, 2, p. 210-213 4 p.

Research output: Article

11 Citations (Scopus)

Follow-up on: optimizing lesion detection in small bowel capsule endoscopy and beyond: from present problems to future solutions

Vasilakakis, M., Koulaouzidis, A., Yung, D. E., Plevris, J. N., Toth, E. & Iakovidis, D. K., febr. 1 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 2, p. 129-141 13 p.

Research output: Article

4 Citations (Scopus)

Forceps Biopsies Are Not Reliable in the Workup of Large Colorectal Lesions Referred for Endoscopic Resection: Should They Be Abandoned?

Rönnow, C. F., Uedo, N., Stenfors, I., Tóth, E. & Thorlacius, H., szept. 1 2019, In : Diseases of the colon and rectum. 62, 9, p. 1063-1070 8 p.

Research output: Article

1 Citation (Scopus)

Genetic counselling and testing of susceptibility genes for therapeutic decision-making in breast cancer—an European consensus statement and expert recommendations

Singer, C. F., Balmaña, J., Bürki, N., Delaloge, S., Filieri, M. E., Gerdes, A. M., Grindedal, E. M., Han, S., Johansson, O., Kaufman, B., Krajc, M., Loman, N., Oláh, E., Paluch-Shimon, S., Plavetic, N. D., Pohlodek, K., Rhiem, K., Teixeira, M. & Evans, D. G., jan. 1 2019, In : European Journal of Cancer. 106, p. 54-60 7 p.

Research output: Article

6 Citations (Scopus)

Kis és közepes kockázatú prosztatarákos betegek sztereotaxiás sugárkezelése CyberKnife gyorsítóval: korai radiogén mellékhatások

Jorgo, K., Ágoston, P., Jánváry, L., Gesztesi, L., Stelczer, G., Kontra, G., Major, T. & Polgár, C., márc. 19 2019, In : Magyar onkologia. 63, 1, p. 52-59 8 p.

Research output: Article

1 Citation (Scopus)

Local immune parameters as potential predictive markers in head and neck squamous cell carcinoma patients receiving induction chemotherapy and cetuximab

Ladányi, A., Kapuvári, B., Papp, E., Tóth, E., Lövey, J., Horváth, K., Gődény, M. & Remenár, É., máj. 2019, In : Head and Neck. 41, 5, p. 1237-1245 9 p.

Research output: Article

2 Citations (Scopus)

Macroscopic appearance of the major duodenal papilla influences bile duct cannulation: a prospective multicenter study by the Scandinavian Association for Digestive Endoscopy Study Group for ERCP

Haraldsson, E., Kylänpää, L., Grönroos, J., Saarela, A., Toth, E., Qvigstad, G., Hult, M., Lindström, O., Laine, S., Karjula, H., Hauge, T., Sadik, R. & Arnelo, U., dec. 2019, In : Gastrointestinal endoscopy. 90, 6, p. 957-963 7 p.

Research output: Article

6 Citations (Scopus)

Measurement of dose exposure of image guidance in external beam accelerated partial breast irradiation: Evaluation of different techniques and linear accelerators

Stelczer, G., Tatai-Szabó, D., Major, T., Mészáros, N., Polgár, C., Pálvölgyi, J. & Pesznyák, C., júl. 1 2019, In : Physica Medica. 63, p. 70-78 9 p.

Research output: Article

2 Citations (Scopus)

Nõgyógyászati tumorok képvezérelt, intenzitásmodulált adjuváns sugárkezelésével szerzett kezdeti tapasztalataink

Király, R., Pesznyák, C., Varga, S., Nguyen, N. A., Major, T. & Polgár, C., jún. 21 2019, In : Magyar onkologia. 64, 2, p. 111-116 6 p.

Research output: Article

Patritumab or placebo, with cetuximab plus platinum therapy in recurrent or metastatic squamous cell carcinoma of the head and neck: A randomised phase II study

Forster, M. D., Dillon, M. T., Kocsis, J., Remenár, É., Pajkos, G., Rolland, F., Greenberg, J. & Harrington, K. J., dec. 2019, In : European Journal of Cancer. 123, p. 36-47 12 p.

Research output: Article

Open Access

Primary Results from SAUL, a Multinational Single-arm Safety Study of Atezolizumab Therapy for Locally Advanced or Metastatic Urothelial or Nonurothelial Carcinoma of the Urinary Tract

Sternberg, C. N., Loriot, Y., James, N., Choy, E., Castellano, D., Lopez-Rios, F., Banna, G. L., De Giorgi, U., Masini, C., Bamias, A., Garcia del Muro, X., Duran, I., Powles, T., Gamulin, M., Zengerling, F., Geczi, L., Gedye, C., de Ducla, S., Fear, S. & Merseburger, A. S., júl. 2019, In : European Urology. 76, 1, p. 73-81 9 p.

Research output: Article

Open Access
17 Citations (Scopus)

Progressive breast fibrosis caused by extreme radiosensitivity: Oncocytogenetic diagnosis and treatment by reconstructive flap surgery

Mészáros, N., Farkas, G., Székely, G., Kocsis, Z. S., Kelemen, P. B., Fodor, J., Polgár, C. & Jurányi, Z., febr. 1 2019, In : Cancer Reports. 2, 1, e1126.

Research output: Article

Quantifying biological effects of radiation from high-energy linear accelerators on lymphocytes

Farkas, G., Kocsis, Z. S., Székely, G., Mihály, D., Pesznyák, C., Pócza, T., Major, T., Polgár, C. & Jurányi, Z., dec. 10 2019, In : Journal of radiation research. 61, 1, p. 73-81 9 p.

Research output: Article

Open Access
Open Access
1 Citation (Scopus)
2 Citations (Scopus)

Safety and Efficacy of Durvalumab with or Without Tremelimumab in Patients with PD-L1-Low/Negative Recurrent or Metastatic HNSCC: The Phase 2 CONDOR Randomized Clinical Trial

Siu, L. L., Even, C., Mesía, R., Remenar, E., Daste, A., Delord, J. P., Krauss, J., Saba, N. F., Nabell, L., Ready, N. E., Braña, I., Kotecki, N., Zandberg, D. P., Gilbert, J., Mehanna, H., Bonomi, M., Jarkowski, A., Melillo, G., Armstrong, J. M., Wildsmith, S. & 1 others, Fayette, J., febr. 2019, In : JAMA Oncology. 5, 2, p. 195-203 9 p.

Research output: Article

38 Citations (Scopus)

Second breast-conserving surgery and interstitial brachytherapy vs. salvage mastectomy for the treatment of local recurrences: 5-year results

Smanykó, V., Mészáros, N., Újhelyi, M., Fröhlich, G., Stelczer, G., Major, T., Mátrai, Z. & Polgár, C., jan. 1 2019, In : Brachytherapy.

Research output: Article

1 Citation (Scopus)

Sentinel lymph node biopsy following previous axillary surgery in recurrent breast cancer

Sávolt, Cserni, G., Lázár, G., Maráz, R., Kelemen, P., Kovács, E., Győrffy, B., Udvarhelyi, N., Vörös, A., Ormándi, K. & Mátrai, Z., okt. 2019, In : European Journal of Surgical Oncology. 45, 10, p. 1835-1838 4 p.

Research output: Article

Sunitinib Rechallenge After Other Targeted Therapies in Metastatic Renal Cell Carcinoma Patients: A Single-Center, Retrospective Study

Nagyiványi, K., Budai, B., Gyergyay, F., Küronya, Z., Bíró, K. & Géczi, L., jún. 1 2019, In : Clinical drug investigation. 39, 6, p. 577-583 7 p.

Research output: Article

Open Access
1 Citation (Scopus)

Survival outcomes of the NeoALTTO study (BIG 1–06): updated results of a randomised multicenter phase III neoadjuvant clinical trial in patients with HER2-positive primary breast cancer

Huober, J., Holmes, E., Baselga, J., de Azambuja, E., Untch, M., Fumagalli, D., Sarp, S., Lang, I., Smith, I., Boyle, F., Xu, B., Lecocq, C., Wildiers, H., Jouannaud, C., Hackman, J., Dasappa, L., Ciruelos, E., Toral Pena, J. C., Adamchuk, H., Hickish, T. & 5 others, de la Pena, L., Jackisch, C., Gelber, R. D., Piccart-Gebhart, M. & Di Cosimo, S., szept. 2019, In : European Journal of Cancer. 118, p. 169-177 9 p.

Research output: Article

3 Citations (Scopus)

Targeted drug combination therapy design based on driver genes

Zsákai, L., Sipos, A., Dobos, J., Eros, D., Szántai-Kis, C., Bánhegyi, P., Pató, J., Orfi, L., Matula, Z., Mikala, G., Kéri, G., Peták, I. & Vályi-Nagy, I., jan. 1 2019, In : Oncotarget. 10, 51, p. 5255-5266 12 p.

Research output: Article

Testicular Cancer in a Lung Transplant Patient With Cystic Fibrosis: A Case Report

Barczi, E., Meszaros, M., Bohacs, A., Géczi, L., Vereczkey, I. & Müller, V., máj. 1 2019, In : Transplantation Proceedings. 51, 4, p. 1293-1295 3 p.

Research output: Article

Tumor-associated disialylated glycosphingolipid antigen-revealing antibodies found in melanoma patients' immunoglobulin repertoire suggest a two-direction regulation mechanism between immune B cells and the tumor

Kotlan, B., Horvath, S., Eles, K., Plotar, V. K., Naszados, G., Czirbesz, K., Blank, M., Farkas, E., Toth, L., Tovari, J., Szekacs, A., Shoenfeld, Y., Godeny, M., Kasler, M. & Liszkay, G., jan. 1 2019, In : Frontiers in immunology. 10, APR, 650.

Research output: Article

Open Access
2018
1 Citation (Scopus)

A CyberKnife sztereotaxiás sugárterápia alkalmazásának lehetõsége fej-nyaki daganatok kezelésében

Jánváry, L. Z., Ferenczi, Ö., Takácsi, N. Z., Bajcsay, A. & Polgár, C., szept. 26 2018, In : Magyar onkologia. 62, 3, p. 180-185 6 p.

Research output: Article

1 Citation (Scopus)