Országos Kémiai Biztonsági Intézet

Research Output 1985 2019

  • 61 Article
  • 1 Conference contribution
2018
5 Citations (Scopus)

Parallel effect of 4-octylphenol and cyclic adenosine monophosphate (cAMP) alters steroidogenesis, cell viability and ROS production in mice Leydig cells

Jambor, T., Greifova, H., Kovacik, A., Kovacikova, E., Tvrda, E., Forgács, Z., Massanyi, P. & Lukac, N., máj. 1 2018, In : Chemosphere. 199, p. 747-754 8 p.

Research output: Article

Leydig Cells
Cholesterol
secretion
Cyclic AMP
Reactive Oxygen Species
2017
1 Citation (Scopus)

Effects of 4-nonylphenol on the steroidogenesis of human adrenocarcinoma cell line (NCI-H295R)

Bistakova, J., Forgács, Z., Bartos, Z., Szivosne, M. R., Jambor, T., Knazicka, Z., Tvrda, E., Libova, L., Goc, Z., Massanyi, P. & Lukac, N., febr. 23 2017, In : Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering. 52, 3, p. 221-227 7 p.

Research output: Article

Cells
Steroid hormones
Hormones
2016
9 Citations (Scopus)

The impact of 4-nonylphenol on the viability and hormone production of mouse Leydig cells

Jambor, T., Lukáčová, J., Tvrdá, E., Kňažická, Z., Forgács, Z. & Lukáč, N., 2016, In : Folia Biologica. 62, 1, p. 34-39 6 p.

Research output: Article

Leydig Cells
Hormones
Testosterone
Androstenedione
Assays
2015
2 Citations (Scopus)
Cytostatic Agents
Thyroid Gland
Chromosome Aberrations
B-Lymphocytes
Working Women
12 Citations (Scopus)
Adrenocortical Carcinoma
Cadmium Chloride
Cadmium
Toxicity
Cells
2013
10 Citations (Scopus)

Effects of mercury on the steroidogenesis of human adrenocarcinoma (NCI-H295R) cell line

Knazicka, Z., Lukac, N., Forgács, Z., Tvrda, E., Lukacova, J., Slivkova, J., Binkowski, Ł. & Massanyi, P., febr. 1 2013, In : Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering. 48, 3, p. 348-353 6 p.

Research output: Article

Cells
Assays
Steroid hormones
Mitochondria
Physiology
2012
30 Citations (Scopus)
Nickel
Toxicity
Calcium
Transcription factors
Mammals
2011
3 Citations (Scopus)
Malathion
Choriocarcinoma
malathion
Gas chromatography
Mass spectrometry
12 Citations (Scopus)

Immunotoxicity monitoring of hospital staff occupationally exposed to cytostatic drugs

Biró, A., Fodor, Z., Major, J. & Tompa, A., jún. 2011, In : Pathology and Oncology Research. 17, 2, p. 301-308 8 p.

Research output: Article

Cytostatic Agents
T-Lymphocytes
Smoking
Lymphocyte Subsets
Antineoplastic Agents
2 Citations (Scopus)
Sister Chromatid Exchange
Chemoprevention
Occupational Health
Primary Prevention
Benzene
2010
34 Citations (Scopus)
Chromosome Aberrations
Formaldehyde
Lymphocytes
Apoptosis
Pathology
2007
15 Citations (Scopus)

Effect of nickel administration in vivo on the testicular structure in male mice

Massányi, P., Lukáč, N., Zemanová, J., Makarevich, A. V., Chrenek, P., Cigánková, V., Flešárová, S., Toman, R., Forgács, Z., Somosy, Z. & Lazor, P., jún. 2007, In : Acta Veterinaria Brno. 76, 2, p. 223-229 7 p.

Research output: Article

Nickel
nickel
Seminiferous Tubules
seminiferous tubules
epithelium
43 Citations (Scopus)

Female reproductive toxicology of cadmium

Massányi, P., Lukáč, N., Uhrín, V., Toman, R., Pivko, J., Rafay, J., Forgács, Z. & Somosy, Z., szept. 2007, In : Acta Biologica Hungarica. 58, 3, p. 287-299 13 p.

Research output: Article

reproductive toxicology
Oviducts
toxicology
oviducts
Cadmium
12 Citations (Scopus)
asphalt
Hungary
Chromosome Aberrations
Health
Petroleum
19 Citations (Scopus)

Lead-induced alterations in rat kidneys and testes in vivo

Massanyi, P., Lukac, N., Makarevich, A. V., Chrenek, P., Forgács, Z., Zakrzewski, M., Stawarz, R., Toman, R., Lazor, P. & Flesarova, S., ápr. 2007, In : Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering. 42, 5, p. 671-676 6 p.

Research output: Article

Rats
Lead
apoptosis
Cell death
Apoptosis
20 Citations (Scopus)

Mercury-induced alterations in rat kidneys and testes in vivo

Massanyi, P., Lukac, N., Slivkova, J., Kovacik, J., Makarevich, A. V., Chrenek, P., Toman, R., Forgács, Z., Somosy, Z., Stawarz, R. & Formicki, G., jún. 2007, In : Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering. 42, 7, p. 865-870 6 p.

Research output: Article

Mercuric Chloride
Mercury
Rats
Blood vessels
Cell death
2006
42 Citations (Scopus)

Altered calcium handling is an early sign of streptozotocin-induced diabetic cardiomyopathy

Ligeti, L., Szenczi, O., Prestia, C. M., Szabó, C., Horváth, K., Marcsek, Z. L., Van Stiphout, R. G. P. M., Van Riel, N. A. W., Den Buijs, J. O., Van Der Vusse, G. J. & Ivanics, T., jún. 2006, In : International Journal of Molecular Medicine. 17, 6, p. 1035-1043 9 p.

Research output: Article

Diabetic Cardiomyopathies
Streptozocin
Ryanodine Receptor Calcium Release Channel
Calcium
Poly(ADP-ribose) Polymerases
18 Citations (Scopus)

Chemical safety and health conditions among Hungarian Hospital Nurses

Tompa, A., Jakab, M., Biró, A., Magyar, B., Fodor, Z., Klupp, T. & Major, J., szept. 2006, Annals of the New York Academy of Sciences. Vol. 1076. p. 635-648 14 p. (Annals of the New York Academy of Sciences; vol. 1076).

Research output: Conference contribution

Chemical Safety
Lymphocytes
Cytostatic Agents
Inhalation Anesthetics
Nurses
4 Citations (Scopus)

Citosztatikumokkal exponált novérek egészségi állapotának jellemzése génés immuntoxikológiai módszerekkel

Tompa, A., Magyar, B., Tóth, F., Biró, A., Fodor, Z., Jakab, M. & Major, J., 2006, In : Magyar Onkologia. 50, 2, p. 153-161 9 p.

Research output: Article

Biomarkers
Nurses
Health
Cytostatic Agents
Iron
54 Citations (Scopus)

Effect of whole-body 1800 MHz GSM-like microwave exposure on testicular steroidogenesis and histology in mice

Forgács, Z., Somosy, Z., Kubinyi, G., Bakos, J., Hudák, A., Surján, A. & Thuróczy, G., júl. 2006, In : Reproductive Toxicology. 22, 1, p. 111-117 7 p.

Research output: Article

Histology
Global system for mobile communications
Microwaves
Leydig Cells
Animals
2005
12 Citations (Scopus)

1800 MHz-es GSM-szerǔ sugárzás hatása hím egerek gonádmǔködésére és hematológiai paramétereire

Zsolt, F., Györgyi, K., Gáborné, S., József, B., Aranka, H., András, S., Csaba, R. & György, T., 2005, In : Magyar Onkologia. 49, 2, p. 149-151 3 p.

Research output: Article

Leydig Cells
Testis
Erythrocyte Count
Hematology
Pituitary Gland
14 Citations (Scopus)
Estrogen Receptors
Cell Line
In Vitro Techniques
resveratrol
2-chloro-N-(ethoxymethyl)-N-(2-methyl-6-(trifluoromethyl)phenyl)acetamide
27 Citations (Scopus)
Risk Management
Benzene
Oils
Sister Chromatid Exchange
Chromosome Aberrations
10 Citations (Scopus)

Ultrastructural changes of ovaries in rabbits following cadmium administration

Massányi, P., Uhrín, V., Toman, R., Pivko, J., Lukáč, N., Forgács, Z., Somosy, Z., Fabiš, M. & Danko, J., 2005, In : Acta Veterinaria Brno. 74, 1, p. 29-35 7 p.

Research output: Article

Cadmium
Ovary
cadmium
rabbits
Rabbits
2004
1 Citation (Scopus)

A kemoprevenció biomarker indikátorai fémexponá ltak körében

Major, J., Jakab, M., Anna, B., Tibor, K., Balázs, M., Katalin, G., Gábor, O., Zoltán, F. & Tompa, A., 2004, In : Magyar Onkologia. 48, 2, p. 125-129 5 p.

Research output: Article

3 Citations (Scopus)
Adherens Junctions
Madin Darby Canine Kidney Cells
Tight Junctions
beta Catenin
Magnetic Fields
4 Citations (Scopus)

Effect of nickel (Ni2+) on primary human ovarian granulosa cells in vitro

Révész, C., Forgács, Z., Lázár, P., Mátyás, S., Rajczy, K., Krizsa, F., Bernard, A. & Gáti, I., szept. 2004, In : Toxicology Mechanisms and Methods. 14, 5, p. 287-292 6 p.

Research output: Article

Granulosa Cells
Nickel
Cyclic AMP Receptors
Progesterone
Cell Survival
25 Citations (Scopus)

Effects of whole-body 50-Hz magnetic field exposure on mouse Leydig cells.

Forgács, Z., Somosy, Z., Kubinyi, G., Sinay, H., Bakos, J., Thuróczy, G., Surján, A., Hudák, A., Olajos, F. & Lázár, P., okt. 20 2004, In : TheScientificWorldJournal [electronic resource]. 4 Suppl 2, p. 83-90 8 p.

Research output: Article

Leydig Cells
Magnetic Fields
Magnetic fields
magnetic field
Chorionic Gonadotropin
16 Citations (Scopus)
Tamoxifen
Estrogen Receptors
Breast Neoplasms
S Phase
Apoptosis
2003
2 Citations (Scopus)
primary contact
Leydig cells
Leydig Cells
Magnetic Fields
magnetic fields
2002
41 Citations (Scopus)
Styrene
Polycyclic Aromatic Hydrocarbons
Benzene
Chromosome Aberrations
Lymphocytes
2001
48 Citations (Scopus)
Antineoplastic Agents
drug
Nurses
Monitoring
monitoring
20 Citations (Scopus)
Leydig Cells
testosterone
Histidine
Testosterone
Amino acids
12 Citations (Scopus)
working conditions
Chromosomes
Aberrations
Chromosome Aberrations
chromosome
2000
20 Citations (Scopus)

Effects of cadmium on ultrastructure and steroidogenesis in cultured porcine ovarian granulosa cells

Massányi, P., Uhrín, V., Sirotkin, A. V., Paksy, K., Forgács, Z., Toman, R. & Kováčik, J., 2000, In : Acta Veterinaria Brno. 69, 2, p. 101-106 6 p.

Research output: Article

steroidogenesis
Granulosa Cells
granulosa cells
Cadmium
cadmium
2 Citations (Scopus)

Influence of sinusoidal 50-Hz magnetic field on cultured human ovarian granulosa cells

Paksy, K., Thuróczy, G., Forgács, Z., Lázár, P. & Gáti, I., 2000, In : Electromagnetic Biology and Medicine. 19, 2, p. 91-97 7 p.

Research output: Article

Granulosa Cells
granulosa cells
Magnetic Fields
magnetic fields
in vitro fertilization
1 Citation (Scopus)

Influence of sinusoidal 50-Hz magnetic field on cultured human ovarian granulosa cells

Paksy, K., Thuróczy, G., Forgács, Z., Lázár, P. & Gáti, I., 2000, In : Electro- and Magnetobiology. 19, 1, p. 91-97 7 p.

Research output: Article

Granulosa Cells
granulosa cells
Magnetic Fields
magnetic fields
in vitro fertilization
11 Citations (Scopus)
Chromosome Breakage
Somatostatin
Chromosome Aberrations
Lymphoid Leukemia
Lymphocytes
1999
16 Citations (Scopus)

In vitro comparative effect of Cd2+, Ni2+, and Co2+ on mouse postblastocyst development

Paksy, K., Forgács, Z. & Gáti, I., máj. 1999, In : Environmental Research. 80, 4, p. 340-347 8 p.

Research output: Article

Trophoblasts
Adhesion
Agglomeration
Cells
Ions
14 Citations (Scopus)
Ethylene Oxide
Hungary
Nurses
Breast Neoplasms
Incidence
39 Citations (Scopus)
Ethylene Oxide
Chromosomal Instability
asphalt
Centromere
Cytostatic Agents
1998
24 Citations (Scopus)
Primary Cell Culture
Leydig Cells
testosterone
Cell culture
Testosterone
32 Citations (Scopus)

Effect of Sinusoidal 50 Hz Magnetic Field on the Testosterone Production of Mouse Primary Leydig Cell Culture

Forgács, Z., Thuróczy, G., Paksy, K. & Szabó, L. D., 1998, In : Bioelectromagnetics. 19, 7, p. 429-431 3 p.

Research output: Article

Leydig cells
Primary Cell Culture
Leydig Cells
Magnetic Fields
magnetic fields
23 Citations (Scopus)
Acrylonitrile
Dimethylformamide
Environmental Monitoring
Sister Chromatid Exchange
chromosome
1997
78 Citations (Scopus)

Effect of cadmium on morphology and steroidogenesis of cultured human ovarian granulosa cells

Paksy, K., Rajczy, K., Forgács, Z., Lázár, P., Bernard, A., Gáti, I. & Kaáli, G. S., szept. 1997, In : Journal of Applied Toxicology. 17, 5, p. 321-327 7 p.

Research output: Article

Granulosa Cells
Cadmium
Follicle Stimulating Hormone
Progesterone
Cadmium Chloride
Chromosome Aberrations
DNA Repair
Population
Mitosis
Hypoxanthine Phosphoribosyltransferase