Xenofuranones A and B: Phenylpyruvate dimers from Xenorhabdus szentirmaii

Alexander O. Brachmann, Steven Forst, Ghazala M. Furgani, Andras Fodor, Helge B. Bode

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Xenofuranones A (1) and B (2) have been isolated from cultures of the insect-pathogenic bacterium Xenorhabdus szentirmaii, and their structures were elucidated by NMR and mass spectroscopy. Both compounds show similarities to fungal furanones, and their biosynthesis was studied using a reversed approach by feeding putative 12C precursors to an overall 13C background in small-scale experiments followed by gas chromatographic analysis coupled to mass spectrometry.

Original languageEnglish
Pages (from-to)1830-1832
Number of pages3
JournalJournal of Natural Products
Issue number12
Publication statusPublished - Dec 1 2006


ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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