Wound healing, haze, and urokinase plasminogen activator after laser vision correction surgery

Adrienne Csutak, David M. Silver, József Tozsér, András Berta

Research output: Contribution to journalArticle

1 Citation (Scopus)


Photorefractive surgery corrects the refractive error of the eye by directly changing the curvature of the front surface of the cornea. Some fraction of the patients who have laser vision correction surgery develop haze (cloudy cornea) after a few weeks to a few months during the wound healing period after surgery. Once haze develops, it can last from weeks to months, with some occurrences lasting more than a year. The condition can be mild to severe, with or without affecting visual acuity. We review our observations and experiments demonstrating that urokinase plasminogen activator ameliorates the occurrence of haze during the corneal wound healing process.

Original languageEnglish
Pages (from-to)198-207
Number of pages10
JournalJohns Hopkins APL Technical Digest (Applied Physics Laboratory)
Issue number3
Publication statusPublished - Dec 1 2007


ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this