White sponge nevus (leukoedema exfoliativum mucosae oris)

Ultrastructural observations

Lars Frithiof, J. Bánóczy

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Biopsy specimens from the oral lesions of white sponge nevus (WSN) in thirteen patients were analyzed by electron microscopy. Several marked deviations from the normal ultrastructure were recorded. Similarities and dissimilarities with other hereditary disturbances affecting the epithelium are discussed. Profound disturbance of the tonofilament system, with atypical aggregation of tonofilaments, was observed. Odland bodies, which are numerous in keratinized epithelia and are extruded into the intercellular space prior to the exfoliation of the surface cells, were also abundant in the WSN specimens. Very little material originating from Odland bodies appears, however, in the intercellular space in WSN. Presumably, the Odland bodies fail to properly function enzymatically in WSN.

Original languageEnglish
Pages (from-to)607-622
Number of pages16
JournalOral Surgery, Oral Medicine, Oral Pathology
Volume41
Issue number5
DOIs
Publication statusPublished - 1976

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Nevus
Porifera
Mucous Membrane
Intermediate Filaments
Extracellular Space
Epithelium
Electron Microscopy
Biopsy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dentistry(all)

Cite this

White sponge nevus (leukoedema exfoliativum mucosae oris) : Ultrastructural observations. / Frithiof, Lars; Bánóczy, J.

In: Oral Surgery, Oral Medicine, Oral Pathology, Vol. 41, No. 5, 1976, p. 607-622.

Research output: Contribution to journalArticle

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