Which knee and probe position determines the final diagnosis of knee inflammation by ultrasound? Results from a European multicenter study

L. Terslev, M. A. Dagostino, M. Brossard, P. Aegerter, P. Bálint, M. Backhaus, G. A. Bruyn, I. Chary-Valckenare, E. Filippucci, J. Freeston, F. Gandjbakhch, A. Iagnocco, S. Jousse-Joulin, P. Mandl, I. Möller, E. Naredo, M. Szkudlarek, R. J. Wakefield, A. Zayat, W. A. Schmidt

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Purpose: To investigate which knee and probe position best identifies knee inflammation and to determine a cut-off level for abnormal synovial effusion. Materials and Methods: 18 experienced sonographers (all rheumatologists) performed ultrasound examinations of the knee joint in patients with knee symptoms and in healthy controls. Each sonographer performed longitudinal suprapatellar ultrasound scans using 9 different configurations at each knee: Midline, parapatallar lateral and parapatellar medial from midline in neutral position (0°) with and without quadriceps muscle contraction and in 30° flexion of the knee. The presence of synovial effusion (SE), the effusion measured in millimeters and the presence of synovial hypertrophy (SH) was noted. Results: A total of 298 knees of 149 subjects (129 patients and 20 controls) were examined. The detection of SH is more sensitive and specific than the detection of SE, independently of the knee and probe position, for the final diagnosis of abnormality. The detection of both synovial hypertrophy and effusion in the knee in neutral position (0°) with quadriceps contraction and with the probe in the midline position, are the best independent predictors for knee abnormalities. Knee effusion >3.2mm measured with the probe in the lateral aspect of the knee is the best diagnostic characteristics for predicting pathological SE. Conclusion: The best combination for detecting SH and SE is obtained by placing the probe in the midline position with the knee in 0° with quadriceps contraction. A cut-off value for pathological effusion may be obtained in the lateral aspect of the knee.

Original languageEnglish
JournalUltraschall in der Medizin
Volume33
Issue number7
DOIs
Publication statusPublished - 2012

Fingerprint

Multicenter Studies
Knee
Inflammation
Synovitis
Quadriceps Muscle
Muscle Contraction
Knee Joint

Keywords

  • arthritis
  • inflammation
  • ultrasound
  • ultrasound-doppler
  • ultrasound-spectral doppler

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Which knee and probe position determines the final diagnosis of knee inflammation by ultrasound? Results from a European multicenter study. / Terslev, L.; Dagostino, M. A.; Brossard, M.; Aegerter, P.; Bálint, P.; Backhaus, M.; Bruyn, G. A.; Chary-Valckenare, I.; Filippucci, E.; Freeston, J.; Gandjbakhch, F.; Iagnocco, A.; Jousse-Joulin, S.; Mandl, P.; Möller, I.; Naredo, E.; Szkudlarek, M.; Wakefield, R. J.; Zayat, A.; Schmidt, W. A.

In: Ultraschall in der Medizin, Vol. 33, No. 7, 2012.

Research output: Contribution to journalArticle

Terslev, L, Dagostino, MA, Brossard, M, Aegerter, P, Bálint, P, Backhaus, M, Bruyn, GA, Chary-Valckenare, I, Filippucci, E, Freeston, J, Gandjbakhch, F, Iagnocco, A, Jousse-Joulin, S, Mandl, P, Möller, I, Naredo, E, Szkudlarek, M, Wakefield, RJ, Zayat, A & Schmidt, WA 2012, 'Which knee and probe position determines the final diagnosis of knee inflammation by ultrasound? Results from a European multicenter study', Ultraschall in der Medizin, vol. 33, no. 7. https://doi.org/10.1055/s-0031-1281973
Terslev, L. ; Dagostino, M. A. ; Brossard, M. ; Aegerter, P. ; Bálint, P. ; Backhaus, M. ; Bruyn, G. A. ; Chary-Valckenare, I. ; Filippucci, E. ; Freeston, J. ; Gandjbakhch, F. ; Iagnocco, A. ; Jousse-Joulin, S. ; Mandl, P. ; Möller, I. ; Naredo, E. ; Szkudlarek, M. ; Wakefield, R. J. ; Zayat, A. ; Schmidt, W. A. / Which knee and probe position determines the final diagnosis of knee inflammation by ultrasound? Results from a European multicenter study. In: Ultraschall in der Medizin. 2012 ; Vol. 33, No. 7.
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abstract = "Purpose: To investigate which knee and probe position best identifies knee inflammation and to determine a cut-off level for abnormal synovial effusion. Materials and Methods: 18 experienced sonographers (all rheumatologists) performed ultrasound examinations of the knee joint in patients with knee symptoms and in healthy controls. Each sonographer performed longitudinal suprapatellar ultrasound scans using 9 different configurations at each knee: Midline, parapatallar lateral and parapatellar medial from midline in neutral position (0°) with and without quadriceps muscle contraction and in 30° flexion of the knee. The presence of synovial effusion (SE), the effusion measured in millimeters and the presence of synovial hypertrophy (SH) was noted. Results: A total of 298 knees of 149 subjects (129 patients and 20 controls) were examined. The detection of SH is more sensitive and specific than the detection of SE, independently of the knee and probe position, for the final diagnosis of abnormality. The detection of both synovial hypertrophy and effusion in the knee in neutral position (0°) with quadriceps contraction and with the probe in the midline position, are the best independent predictors for knee abnormalities. Knee effusion >3.2mm measured with the probe in the lateral aspect of the knee is the best diagnostic characteristics for predicting pathological SE. Conclusion: The best combination for detecting SH and SE is obtained by placing the probe in the midline position with the knee in 0° with quadriceps contraction. A cut-off value for pathological effusion may be obtained in the lateral aspect of the knee.",
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T1 - Which knee and probe position determines the final diagnosis of knee inflammation by ultrasound? Results from a European multicenter study

AU - Terslev, L.

AU - Dagostino, M. A.

AU - Brossard, M.

AU - Aegerter, P.

AU - Bálint, P.

AU - Backhaus, M.

AU - Bruyn, G. A.

AU - Chary-Valckenare, I.

AU - Filippucci, E.

AU - Freeston, J.

AU - Gandjbakhch, F.

AU - Iagnocco, A.

AU - Jousse-Joulin, S.

AU - Mandl, P.

AU - Möller, I.

AU - Naredo, E.

AU - Szkudlarek, M.

AU - Wakefield, R. J.

AU - Zayat, A.

AU - Schmidt, W. A.

PY - 2012

Y1 - 2012

N2 - Purpose: To investigate which knee and probe position best identifies knee inflammation and to determine a cut-off level for abnormal synovial effusion. Materials and Methods: 18 experienced sonographers (all rheumatologists) performed ultrasound examinations of the knee joint in patients with knee symptoms and in healthy controls. Each sonographer performed longitudinal suprapatellar ultrasound scans using 9 different configurations at each knee: Midline, parapatallar lateral and parapatellar medial from midline in neutral position (0°) with and without quadriceps muscle contraction and in 30° flexion of the knee. The presence of synovial effusion (SE), the effusion measured in millimeters and the presence of synovial hypertrophy (SH) was noted. Results: A total of 298 knees of 149 subjects (129 patients and 20 controls) were examined. The detection of SH is more sensitive and specific than the detection of SE, independently of the knee and probe position, for the final diagnosis of abnormality. The detection of both synovial hypertrophy and effusion in the knee in neutral position (0°) with quadriceps contraction and with the probe in the midline position, are the best independent predictors for knee abnormalities. Knee effusion >3.2mm measured with the probe in the lateral aspect of the knee is the best diagnostic characteristics for predicting pathological SE. Conclusion: The best combination for detecting SH and SE is obtained by placing the probe in the midline position with the knee in 0° with quadriceps contraction. A cut-off value for pathological effusion may be obtained in the lateral aspect of the knee.

AB - Purpose: To investigate which knee and probe position best identifies knee inflammation and to determine a cut-off level for abnormal synovial effusion. Materials and Methods: 18 experienced sonographers (all rheumatologists) performed ultrasound examinations of the knee joint in patients with knee symptoms and in healthy controls. Each sonographer performed longitudinal suprapatellar ultrasound scans using 9 different configurations at each knee: Midline, parapatallar lateral and parapatellar medial from midline in neutral position (0°) with and without quadriceps muscle contraction and in 30° flexion of the knee. The presence of synovial effusion (SE), the effusion measured in millimeters and the presence of synovial hypertrophy (SH) was noted. Results: A total of 298 knees of 149 subjects (129 patients and 20 controls) were examined. The detection of SH is more sensitive and specific than the detection of SE, independently of the knee and probe position, for the final diagnosis of abnormality. The detection of both synovial hypertrophy and effusion in the knee in neutral position (0°) with quadriceps contraction and with the probe in the midline position, are the best independent predictors for knee abnormalities. Knee effusion >3.2mm measured with the probe in the lateral aspect of the knee is the best diagnostic characteristics for predicting pathological SE. Conclusion: The best combination for detecting SH and SE is obtained by placing the probe in the midline position with the knee in 0° with quadriceps contraction. A cut-off value for pathological effusion may be obtained in the lateral aspect of the knee.

KW - arthritis

KW - inflammation

KW - ultrasound

KW - ultrasound-doppler

KW - ultrasound-spectral doppler

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U2 - 10.1055/s-0031-1281973

DO - 10.1055/s-0031-1281973

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