What do we know about the diagnostics, treatment and epidemiology of Clostridioides (Clostridium) difficile infection in Europe?

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Clostridium difficile, recently reclassified as Clostridioides difficile is responsible for a significant part of diarrheal diseases in the hospitals and in the community. Besides the main pathogenic factors, toxin A, toxin B and the binary toxin, several other putative virulence factors have been investigated. This manuscript summarize recent findings in Europe concerning source of infection, epidemiology of CDI, the changing pattern of PCR ribotypes of C. difficile strains in different European countries, recommendations for diagnosis and treatment of CDI.

Original languageEnglish
Pages (from-to)164-170
Number of pages7
JournalJournal of Infection and Chemotherapy
Volume24
Issue number3
DOIs
Publication statusPublished - Mar 1 2018

Fingerprint

Clostridium Infections
Clostridium difficile
Epidemiology
Ribotyping
Virulence Factors
Polymerase Chain Reaction
Infection

Keywords

  • Clostridioides difficile
  • Diagnostics
  • Epidemiology
  • European perspective
  • Pathogenesis
  • Therapy

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

@article{ede5528b8eaa401a8d69ff2039eeead7,
title = "What do we know about the diagnostics, treatment and epidemiology of Clostridioides (Clostridium) difficile infection in Europe?",
abstract = "Clostridium difficile, recently reclassified as Clostridioides difficile is responsible for a significant part of diarrheal diseases in the hospitals and in the community. Besides the main pathogenic factors, toxin A, toxin B and the binary toxin, several other putative virulence factors have been investigated. This manuscript summarize recent findings in Europe concerning source of infection, epidemiology of CDI, the changing pattern of PCR ribotypes of C. difficile strains in different European countries, recommendations for diagnosis and treatment of CDI.",
keywords = "Clostridioides difficile, Diagnostics, Epidemiology, European perspective, Pathogenesis, Therapy",
author = "E. Nagy",
year = "2018",
month = "3",
day = "1",
doi = "10.1016/j.jiac.2017.12.003",
language = "English",
volume = "24",
pages = "164--170",
journal = "Journal of Infection and Chemotherapy",
issn = "1341-321X",
publisher = "Elsevier BV",
number = "3",

}

TY - JOUR

T1 - What do we know about the diagnostics, treatment and epidemiology of Clostridioides (Clostridium) difficile infection in Europe?

AU - Nagy, E.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Clostridium difficile, recently reclassified as Clostridioides difficile is responsible for a significant part of diarrheal diseases in the hospitals and in the community. Besides the main pathogenic factors, toxin A, toxin B and the binary toxin, several other putative virulence factors have been investigated. This manuscript summarize recent findings in Europe concerning source of infection, epidemiology of CDI, the changing pattern of PCR ribotypes of C. difficile strains in different European countries, recommendations for diagnosis and treatment of CDI.

AB - Clostridium difficile, recently reclassified as Clostridioides difficile is responsible for a significant part of diarrheal diseases in the hospitals and in the community. Besides the main pathogenic factors, toxin A, toxin B and the binary toxin, several other putative virulence factors have been investigated. This manuscript summarize recent findings in Europe concerning source of infection, epidemiology of CDI, the changing pattern of PCR ribotypes of C. difficile strains in different European countries, recommendations for diagnosis and treatment of CDI.

KW - Clostridioides difficile

KW - Diagnostics

KW - Epidemiology

KW - European perspective

KW - Pathogenesis

KW - Therapy

UR - http://www.scopus.com/inward/record.url?scp=85039054908&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85039054908&partnerID=8YFLogxK

U2 - 10.1016/j.jiac.2017.12.003

DO - 10.1016/j.jiac.2017.12.003

M3 - Review article

VL - 24

SP - 164

EP - 170

JO - Journal of Infection and Chemotherapy

JF - Journal of Infection and Chemotherapy

SN - 1341-321X

IS - 3

ER -