Volume estimation in dialysis patients: The concordance of brain-type natriuretic peptide measurements and bioimpedance values

Mihály Tapolyai, Mária Faludi, Virág Réti, Zsolt Lengvárszky, Tibor Szarvas, Tibor Fülöp, G. Bekő, Klára Berta

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Correct estimation of the dialysis patients' hydration status remains an important clinical challenge. Bioimpedance measurements have been validated by various physiological tests, and the use of brain-type natriuretic peptide (BNP) has been validated by inferior vena cava diameter measurements. This is an observational cohort study that evaluated the correspondence between bioimpedance-measured overhydration percentage (OH%) and BNP. We measured predialysis OH% by bioimpedance apparatus (Body Composition Monitor) and BNP by microparticle enzyme-linked immunoassay in 41 prevalent stable hemodialysis patients, 19 (46%) women, aged 58.9±14.5 years. The cohort's average BNP was 2694±3278pg/mL and 10 (24.4%) of these 41 patients had BNP0.097x, predicting a BNP of 216.4pg/mL at 0% overhydration status (r 0.61). Receiver-operating curves revealed an area under the curve of 0.885 for BNP when the OH% was set ≥15% of overhydration and an area under the curve of 0.918 for OH% when the BNP was set ≥500pg/mL for being abnormal. We conclude that in our cohort there was a high degree of correspondence between these two tests with an exponential relationship between the measurements.

Original languageEnglish
Pages (from-to)406-412
Number of pages7
JournalHemodialysis International
Volume17
Issue number3
DOIs
Publication statusPublished - Jul 2013

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Brain Natriuretic Peptide
Dialysis
Area Under Curve
Inferior Vena Cava
Body Composition
Immunoenzyme Techniques
Observational Studies
Renal Dialysis
Cohort Studies

Keywords

  • Bioimpedance
  • Dry weight
  • End-stage renal disease
  • Natriuretic peptides
  • Volume overload

ASJC Scopus subject areas

  • Hematology
  • Nephrology

Cite this

Volume estimation in dialysis patients : The concordance of brain-type natriuretic peptide measurements and bioimpedance values. / Tapolyai, Mihály; Faludi, Mária; Réti, Virág; Lengvárszky, Zsolt; Szarvas, Tibor; Fülöp, Tibor; Bekő, G.; Berta, Klára.

In: Hemodialysis International, Vol. 17, No. 3, 07.2013, p. 406-412.

Research output: Contribution to journalArticle

Tapolyai, Mihály ; Faludi, Mária ; Réti, Virág ; Lengvárszky, Zsolt ; Szarvas, Tibor ; Fülöp, Tibor ; Bekő, G. ; Berta, Klára. / Volume estimation in dialysis patients : The concordance of brain-type natriuretic peptide measurements and bioimpedance values. In: Hemodialysis International. 2013 ; Vol. 17, No. 3. pp. 406-412.
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