Vogt-Koyanagi-Harada disease presenting initially as aseptic meningoencephalitis

A. Kamondi, A. Szegedi, A. Papp, A. Seres, I. Szirmai

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Vogt-Koyanagi-Harada (VKH) disease in a Gypsy woman was diagnosed 4 months after her initial complaints. The delay is explained by the facts that: (1) the characteristic ophthalmological symptoms, which usually herald the disease and ensure early diagnosis, developed only late during the course; and (2) only retrospective analysis of the cerebrospinal fluid (CSF) cell preparation proved the presence of melanin-laden macrophages (MLMs), specific for the syndrome. We emphasize that VKH syndrome may initially present as aseptic meningitis, without specific ophthalmological symptoms. In suspected cases a very detailed CSF cell analysis is needed, because the presence of MLMs could confirm the diagnosis. However, VKH syndrome has a much higher incidence in Asia; cases in other races, including white people in Europe, also occur.

Original languageEnglish
Pages (from-to)719-722
Number of pages4
JournalEuropean Journal of Neurology
Volume7
Issue number6
DOIs
Publication statusPublished - 2000

Fingerprint

Uveomeningoencephalitic Syndrome
Meningoencephalitis
Melanins
Cerebrospinal Fluid
Macrophages
Roma
Aseptic Meningitis
Early Diagnosis
Incidence

Keywords

  • Immunoglobulin treatment
  • Melanin-laden macrophages
  • Meningoencephalitis
  • Pleocytosis
  • Vogt-Koyanagi-Harada disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Vogt-Koyanagi-Harada disease presenting initially as aseptic meningoencephalitis. / Kamondi, A.; Szegedi, A.; Papp, A.; Seres, A.; Szirmai, I.

In: European Journal of Neurology, Vol. 7, No. 6, 2000, p. 719-722.

Research output: Contribution to journalArticle

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