D-vitamin-szint mérése hazai gyulladásos bélbetegekben

Translated title of the contribution: Vitamin D level in Hungarian patients with inflammatory bowel diseases

Katalin Lorinczy, Péter László Lakatos, Miklós Tóth, Ágnes Salamon, Adrienn Nemes, Ágnes Anna Csontos, Bálint Fekete, Orsolya Terjék, László Herszényi, Márk Juhász, Zsolt Tulassay, Pál Miheller

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: Vitamin D has an important role in the immune regulation. Vitamin D is essential for innate and adaptive immune systems and it plays a significant role in the formation of immune tolerance, as well. Aim: Vitamin D deficiency has been observed in patients with inflammatory bowel diseases in Western Europe, but there is no data available from Eastern Europe. Method: The study included 169 patients with inflammatory bowel disease. Results: The median vitamin D level was 22.7±10.6 ng/ml. Only 20% of the patients had adequate vitamin D level (>30 ng/ml), 52% had vitamin D insufficiency (15-30 ng/ml), and 28% of them had severe vitamin D deficiency (<15 ng/ml). Vitamin D concentration failed to correlate with clinical activity indexes (partial Mayo score: r = -0.143; Crohn's disease activity index: r = -0.253) and with inflammatory parameters (C-reactive protein: r = 0.008; erythrocyte sedimentation rate: r = 0.012). Conclusions: Since vitamin D deficiency can be frequently observed in Hungarian patients with inflammatory bowel disease, its level should be tested in these patients. Orv. Hetil., 154(46), 1821-1828.

Original languageHungarian
Pages (from-to)1821-1828
Number of pages8
JournalOrvosi hetilap
Volume154
Issue number46
DOIs
Publication statusPublished - Nov 1 2013

    Fingerprint

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lorinczy, K., Lakatos, P. L., Tóth, M., Salamon, Á., Nemes, A., Csontos, Á. A., Fekete, B., Terjék, O., Herszényi, L., Juhász, M., Tulassay, Z., & Miheller, P. (2013). D-vitamin-szint mérése hazai gyulladásos bélbetegekben. Orvosi hetilap, 154(46), 1821-1828. https://doi.org/10.1556/OH.2013.29750