Visually evoked cerebral vasomotor response in smoking and nonsmoking young adults, investigated by functional transcranial doppler

L. Oláh, Yaron Raiter, Claudia Candale, Sándor Molnár, Bernhard Rosengarten, Natan Bornstein, L. Csiba

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Smoking has been known to cause endothelial dysfunction and is an important risk factor for ischemic stroke. In our study we investigated whether chronic cigarette smoking affects the cerebral blood flow velocity response to a physiological, visual stimulus. By using a visual cortex stimulation paradigm, the flow velocity response in the posterior cerebral arteries (PCA) was measured bilaterally, in 32 young healthy adults (16 smokers, 16 nonsmokers). The stimulation protocol consisted of 10 cycles with a resting phase of 20 s and a stimulating phase of 40 s for each cycle. Besides functional transcranial Doppler (TCD), laboratory tests and measurement of intima-media-thickness (IMT) were also performed. Repeated-measure analysis of variance (ANOVA) was used to detect differences in visually evoked relative flow velocity time courses between smokers and nonsmokers. Repeated-measure ANOVA revealed marked difference in the peak systolic flow velocity time courses between smokers and nonsmokers (p

Original languageEnglish
Pages (from-to)353-358
Number of pages6
JournalNicotine and Tobacco Research
Volume10
Issue number2
DOIs
Publication statusPublished - Feb 2008

Fingerprint

Young Adult
Cerebrovascular Circulation
Analysis of Variance
Smoking
Posterior Cerebral Artery
Photic Stimulation
Blood Flow Velocity
Visual Cortex
Stroke

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Visually evoked cerebral vasomotor response in smoking and nonsmoking young adults, investigated by functional transcranial doppler. / Oláh, L.; Raiter, Yaron; Candale, Claudia; Molnár, Sándor; Rosengarten, Bernhard; Bornstein, Natan; Csiba, L.

In: Nicotine and Tobacco Research, Vol. 10, No. 2, 02.2008, p. 353-358.

Research output: Contribution to journalArticle

Oláh, L. ; Raiter, Yaron ; Candale, Claudia ; Molnár, Sándor ; Rosengarten, Bernhard ; Bornstein, Natan ; Csiba, L. / Visually evoked cerebral vasomotor response in smoking and nonsmoking young adults, investigated by functional transcranial doppler. In: Nicotine and Tobacco Research. 2008 ; Vol. 10, No. 2. pp. 353-358.
@article{fb5781639c1a43199957f870cb12387a,
title = "Visually evoked cerebral vasomotor response in smoking and nonsmoking young adults, investigated by functional transcranial doppler",
abstract = "Smoking has been known to cause endothelial dysfunction and is an important risk factor for ischemic stroke. In our study we investigated whether chronic cigarette smoking affects the cerebral blood flow velocity response to a physiological, visual stimulus. By using a visual cortex stimulation paradigm, the flow velocity response in the posterior cerebral arteries (PCA) was measured bilaterally, in 32 young healthy adults (16 smokers, 16 nonsmokers). The stimulation protocol consisted of 10 cycles with a resting phase of 20 s and a stimulating phase of 40 s for each cycle. Besides functional transcranial Doppler (TCD), laboratory tests and measurement of intima-media-thickness (IMT) were also performed. Repeated-measure analysis of variance (ANOVA) was used to detect differences in visually evoked relative flow velocity time courses between smokers and nonsmokers. Repeated-measure ANOVA revealed marked difference in the peak systolic flow velocity time courses between smokers and nonsmokers (p",
author = "L. Ol{\'a}h and Yaron Raiter and Claudia Candale and S{\'a}ndor Moln{\'a}r and Bernhard Rosengarten and Natan Bornstein and L. Csiba",
year = "2008",
month = "2",
doi = "10.1080/14622200701825874",
language = "English",
volume = "10",
pages = "353--358",
journal = "Nicotine and Tobacco Research",
issn = "1462-2203",
publisher = "Oxford University Press",
number = "2",

}

TY - JOUR

T1 - Visually evoked cerebral vasomotor response in smoking and nonsmoking young adults, investigated by functional transcranial doppler

AU - Oláh, L.

AU - Raiter, Yaron

AU - Candale, Claudia

AU - Molnár, Sándor

AU - Rosengarten, Bernhard

AU - Bornstein, Natan

AU - Csiba, L.

PY - 2008/2

Y1 - 2008/2

N2 - Smoking has been known to cause endothelial dysfunction and is an important risk factor for ischemic stroke. In our study we investigated whether chronic cigarette smoking affects the cerebral blood flow velocity response to a physiological, visual stimulus. By using a visual cortex stimulation paradigm, the flow velocity response in the posterior cerebral arteries (PCA) was measured bilaterally, in 32 young healthy adults (16 smokers, 16 nonsmokers). The stimulation protocol consisted of 10 cycles with a resting phase of 20 s and a stimulating phase of 40 s for each cycle. Besides functional transcranial Doppler (TCD), laboratory tests and measurement of intima-media-thickness (IMT) were also performed. Repeated-measure analysis of variance (ANOVA) was used to detect differences in visually evoked relative flow velocity time courses between smokers and nonsmokers. Repeated-measure ANOVA revealed marked difference in the peak systolic flow velocity time courses between smokers and nonsmokers (p

AB - Smoking has been known to cause endothelial dysfunction and is an important risk factor for ischemic stroke. In our study we investigated whether chronic cigarette smoking affects the cerebral blood flow velocity response to a physiological, visual stimulus. By using a visual cortex stimulation paradigm, the flow velocity response in the posterior cerebral arteries (PCA) was measured bilaterally, in 32 young healthy adults (16 smokers, 16 nonsmokers). The stimulation protocol consisted of 10 cycles with a resting phase of 20 s and a stimulating phase of 40 s for each cycle. Besides functional transcranial Doppler (TCD), laboratory tests and measurement of intima-media-thickness (IMT) were also performed. Repeated-measure analysis of variance (ANOVA) was used to detect differences in visually evoked relative flow velocity time courses between smokers and nonsmokers. Repeated-measure ANOVA revealed marked difference in the peak systolic flow velocity time courses between smokers and nonsmokers (p

UR - http://www.scopus.com/inward/record.url?scp=38849083948&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38849083948&partnerID=8YFLogxK

U2 - 10.1080/14622200701825874

DO - 10.1080/14622200701825874

M3 - Article

C2 - 18236300

AN - SCOPUS:38849083948

VL - 10

SP - 353

EP - 358

JO - Nicotine and Tobacco Research

JF - Nicotine and Tobacco Research

SN - 1462-2203

IS - 2

ER -