A simple cell homogenate fractionation procedure was used to enrich for virus-specific reverse transcriptase. Animal cells infected with Rauscher leukaemic viruses provided the positive controls necessary to establish guidelines for fractionation, enzyme preparation and assay of human malignant cells. In the peripheral blood of five acute lymphoblastic leukaemic children we found no evidence to support the presence of any oncorna viruses. The results obtained with acute leukaemic lymphoblasts and with healthy thymocytes were similar.
|Number of pages||10|
|Journal||Acta paediatrica Academiae Scientiarum Hungaricae|
|Publication status||Published - Dec 1 1981|
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