Virus-specific reverse transcriptase in acute leukaemia

S. Kiss, D. Schuler

Research output: Contribution to journalArticle

Abstract

A simple cell homogenate fractionation procedure was used to enrich for virus-specific reverse transcriptase. Animal cells infected with Rauscher leukaemic viruses provided the positive controls necessary to establish guidelines for fractionation, enzyme preparation and assay of human malignant cells. In the peripheral blood of five acute lymphoblastic leukaemic children we found no evidence to support the presence of any oncorna viruses. The results obtained with acute leukaemic lymphoblasts and with healthy thymocytes were similar.

Original languageEnglish
Pages (from-to)33-42
Number of pages10
JournalActa paediatrica Academiae Scientiarum Hungaricae
Volume22
Issue number1-2
Publication statusPublished - Dec 1 1981

ASJC Scopus subject areas

  • Medicine(all)

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