Video capsule colonoscopy in routine clinical practice

E. Tóth, Diana E. Yung, Artur Nemeth, Gabriele Wurm Johansson, Henrik Thorlacius, Anastasios Koulaouzidis

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Colon capsule endoscopy (CCE) offers direct mucosal visualisation without sedation or gas insufflation required in conventional colonoscopy (CC). However, evidence for the role of CCE as an adjunct or alternative to CC remains equivocal. In this observational cohort study, we report our experience of using CCE to investigate patients with suspected colon pathology at a tertiary referral centre. Methods: From 2007-2015, consecutive patients requiring colonoscopy were recruited from a tertiary care centre in Malmo, Sweden. Data collected: patient demographics, indication for CCE, findings, bowel cleansing, colon transit time (CTT) and completeness of colon examination. Results: Seventy-seven patients (57 F/20 F, median age 56 years) were included. The reason for CCE was previously incomplete or refused CC in 39 and 26 cases, and follow up of previous findings in 12 cases, respectively. The main clinical indications were gastrointestinal (GI) bleeding (n=28; 36%) and suspected inflammatory bowel disease (IBD) or follow-up of known IBD (n=23; 30%). CCE was complete in 58/77 (75%) patients. In 3 patients the colon was not reached; in the other 16, the capsule reached the rectum (n=4), sigmoid (n=6), descending colon (n=5) and transverse colon (n=1). Findings were: normal CCE (n=15; 19%) colonic diverticula (n=29; 38%), polyps (n=17; 22%), active IBD (n=12; 16%), haemorrhoids (n=8; 10%), colonic angioectasia (n=4; 5%) and cancer (n=1; 1%). Small-bowel findings were recorded in 8 (10%) patients. All patients tolerated bowel preparation and CCE well. Two patients with an ulcerated small-bowel stricture and cancer respectively experienced temporary capsule retention with spontaneous resolution. Conclusions: CCE is a well-tolerated alternative to CC, but requires technological improvement and optimisation of clinical practice to meet current reference standards. Although further technical development is required, CCE may complement or even replace CC for certain clinical indications.

Original languageEnglish
Article number195
JournalAnnals of Translational Medicine
Volume5
Issue number9
DOIs
Publication statusPublished - May 1 2017

Fingerprint

Colonoscopy
Capsule Endoscopy
Capsules
Colon
Tertiary Care Centers
Colon Diverticula
Descending Colon
Hemorrhoids
Transverse Colon
Insufflation
Sigmoid Colon
Polyps
Inflammatory Bowel Diseases
Rectum
Sweden
Observational Studies
Neoplasms
Pathologic Constriction
Cohort Studies
Gases

Keywords

  • Capsule colonoscopy
  • Colon capsule endoscopy (CCE)
  • Colorectal cancer (CRC)
  • Gastrointestinal (GI) bleeding
  • Inflammatory bowel disease (IBD)

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tóth, E., Yung, D. E., Nemeth, A., Johansson, G. W., Thorlacius, H., & Koulaouzidis, A. (2017). Video capsule colonoscopy in routine clinical practice. Annals of Translational Medicine, 5(9), [195]. https://doi.org/10.21037/atm.2017.03.91

Video capsule colonoscopy in routine clinical practice. / Tóth, E.; Yung, Diana E.; Nemeth, Artur; Johansson, Gabriele Wurm; Thorlacius, Henrik; Koulaouzidis, Anastasios.

In: Annals of Translational Medicine, Vol. 5, No. 9, 195, 01.05.2017.

Research output: Contribution to journalArticle

Tóth, E, Yung, DE, Nemeth, A, Johansson, GW, Thorlacius, H & Koulaouzidis, A 2017, 'Video capsule colonoscopy in routine clinical practice', Annals of Translational Medicine, vol. 5, no. 9, 195. https://doi.org/10.21037/atm.2017.03.91
Tóth E, Yung DE, Nemeth A, Johansson GW, Thorlacius H, Koulaouzidis A. Video capsule colonoscopy in routine clinical practice. Annals of Translational Medicine. 2017 May 1;5(9). 195. https://doi.org/10.21037/atm.2017.03.91
Tóth, E. ; Yung, Diana E. ; Nemeth, Artur ; Johansson, Gabriele Wurm ; Thorlacius, Henrik ; Koulaouzidis, Anastasios. / Video capsule colonoscopy in routine clinical practice. In: Annals of Translational Medicine. 2017 ; Vol. 5, No. 9.
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