Vibrational spectroscopic detection of beta- and gamma-turns in synthetic and natural peptides and proteins

Elemér Vass, Miklós Hollósi, Françoise Besson, René Buchet

Research output: Contribution to journalArticle

230 Citations (Scopus)

Abstract

Vibrational spectroscopy of polypeptides and proteins can reveal their overall structure and details of their local conformations resulting from the formation of hydrogen bonds or deformation of chemical bonds. The dual nature of information of obtained from IR and Raman spectroscopies allow to expand the application of vibrational spectroscopy to various chemical and biological problems but also to support the interpretation of vibrational spectra. This paper discusses the problems related with the contribution of turns to the vibrational spectra of polypeptides and with the estimation of turn content.

Original languageEnglish
Pages (from-to)1917-1954
Number of pages38
JournalChemical reviews
Volume103
Issue number5
DOIs
Publication statusPublished - May 2003

ASJC Scopus subject areas

  • Chemistry(all)

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