Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion

E. Mezey, J. Z. Kiss

Research output: Contribution to journalArticle

139 Citations (Scopus)

Abstract

Vasoactive intestinal polypeptide (VIP) immunoreactivity is present in varicosities and fibers in the hypothalamic paraventricular nucleus (PVN) in normal control animals. Adrenalectomy and lactation combined with colchicine treatment results in the appearance of a large population of VIP-immunopositive cell bodies in the parvocellular part of the PVN. Adrenalectomy, as well as lactation, significantly increases the number of VIP-positive fibers in the external zone of the median eminence. These observations suggest that the VIP-immunopositive neurons in the PVN may participate in regulating prolactin and corticotropin secretion.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalProceedings of the National Academy of Sciences of the United States of America
Volume82
Issue number1
DOIs
Publication statusPublished - 1985
Externally publishedYes

ASJC Scopus subject areas

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