Various signal molecules modulate voltage-activated ion currents on snail neurons.

A. Szücs, G. B. Stefano, T. K. Hughes, K. S. Rózsa

Research output: Contribution to journalArticle

Abstract

The modulatory effects of interleukin-1 (IL-1), an immunotransmitter, and FMRFamide, a molluscan neuropeptide, were studied on identified neurons of Helix pomatia L. (Mollusca, Gastropoda) by using the method of two microelectrode voltage clamp. IL-1 and FMRFamide uniformly decreased the voltage-activated inward current (ICa), while the voltage-dependent outward potassium current (Inet K) increased. IL-1 and FMRFamide were shown to use the same cellular targets as used by the low molecular weight neurotransmitters.

Original languageEnglish
Pages (from-to)139-143
Number of pages5
JournalActa Biochimica et Biophysica Hungarica
Volume26
Issue number1-4
Publication statusPublished - 1991

Fingerprint

FMRFamide
Snails
Interleukin-1
Neurons
Ions
Molecules
Electric potential
Gastropoda
Mollusca
Microelectrodes
Clamping devices
Neuropeptides
Neurotransmitter Agents
Potassium
Molecular Weight
Molecular weight

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry

Cite this

Various signal molecules modulate voltage-activated ion currents on snail neurons. / Szücs, A.; Stefano, G. B.; Hughes, T. K.; Rózsa, K. S.

In: Acta Biochimica et Biophysica Hungarica, Vol. 26, No. 1-4, 1991, p. 139-143.

Research output: Contribution to journalArticle

Szücs, A. ; Stefano, G. B. ; Hughes, T. K. ; Rózsa, K. S. / Various signal molecules modulate voltage-activated ion currents on snail neurons. In: Acta Biochimica et Biophysica Hungarica. 1991 ; Vol. 26, No. 1-4. pp. 139-143.
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