GONADOTROPIN RELEASING HORMON TERHELESES TESZTRE KAPOTT HYPOPHYSEALIS VALASZ ERTEKELESE OLIGOZOOSPERMIA ESETEBEN

Translated title of the contribution: Valuation of the hypophyseal response to the gonadotrophin releasing hormone loading test in case of oligozoospermia

S. Koloszar, J. Szöllősi

Research output: Contribution to journalArticle

Abstract

Twenty-two infertile men with oligozoospermia were selected for gonadotrophin releasing hormone loading test. Prior to the test semen analyses, ultrasound examination of the testis and plasma FSH, LH, prolactin and testosterone determination were performed in ail cases. The basal values of FSH, LH and prolactin were (0.23-2.84 IU/l), (0.81-6.42 IU/l), (116-398 mU/l), respectively. During the test 100 mcg GnRH (Lutrelef®, Ferring) was given intravenously and blood samples were taken in every 15, 30, 60, 90, 120, 180 minutes after the injection. Plasma FSH, LH, prolactin and testosterone levels were measured by RIA method. In 11 case (1st group) hypophyseal response was reactive (increase in FSH 2-fold and LH 4-fold or more). The average increase in FSH in 6 cases (1.5-fold: 2nd group) and in LH 5 cases (2.5-3.0-fold: 3rd group) was less than in normal conditions. Our data demonstrate that in case of reactive GnRH loading test the pulsatile GnRH (1st group), pure FSH i.m. (2nd group) and human menopausal gonadotrophin i.m. or human chorionic gonadotrophin i.m. (3rd group) administration is the applicable hormone treatment strategy in case of oligozoospermia.

Original languageHungarian
Pages (from-to)361-363
Number of pages3
JournalMagyar Noorvosok Lapja
Volume58
Issue number5
Publication statusPublished - 1995

Fingerprint

Oligospermia
Gonadotropin-Releasing Hormone
Prolactin
Testosterone
Menotropins
Semen Analysis
Chorionic Gonadotropin
Testis
Hormones
Injections
Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

GONADOTROPIN RELEASING HORMON TERHELESES TESZTRE KAPOTT HYPOPHYSEALIS VALASZ ERTEKELESE OLIGOZOOSPERMIA ESETEBEN. / Koloszar, S.; Szöllősi, J.

In: Magyar Noorvosok Lapja, Vol. 58, No. 5, 1995, p. 361-363.

Research output: Contribution to journalArticle

@article{9b89a23bdfb1411e8a09dc43990750be,
title = "GONADOTROPIN RELEASING HORMON TERHELESES TESZTRE KAPOTT HYPOPHYSEALIS VALASZ ERTEKELESE OLIGOZOOSPERMIA ESETEBEN",
abstract = "Twenty-two infertile men with oligozoospermia were selected for gonadotrophin releasing hormone loading test. Prior to the test semen analyses, ultrasound examination of the testis and plasma FSH, LH, prolactin and testosterone determination were performed in ail cases. The basal values of FSH, LH and prolactin were (0.23-2.84 IU/l), (0.81-6.42 IU/l), (116-398 mU/l), respectively. During the test 100 mcg GnRH (Lutrelef{\circledR}, Ferring) was given intravenously and blood samples were taken in every 15, 30, 60, 90, 120, 180 minutes after the injection. Plasma FSH, LH, prolactin and testosterone levels were measured by RIA method. In 11 case (1st group) hypophyseal response was reactive (increase in FSH 2-fold and LH 4-fold or more). The average increase in FSH in 6 cases (1.5-fold: 2nd group) and in LH 5 cases (2.5-3.0-fold: 3rd group) was less than in normal conditions. Our data demonstrate that in case of reactive GnRH loading test the pulsatile GnRH (1st group), pure FSH i.m. (2nd group) and human menopausal gonadotrophin i.m. or human chorionic gonadotrophin i.m. (3rd group) administration is the applicable hormone treatment strategy in case of oligozoospermia.",
keywords = "Gonadotrophin releasing hormone, Loading test, Oligozoospermia",
author = "S. Koloszar and J. Sz{\"o}llősi",
year = "1995",
language = "Hungarian",
volume = "58",
pages = "361--363",
journal = "Magyar Noorvosok Lapja",
issn = "0025-021X",
publisher = "Magyar Noovos Tarsasag",
number = "5",

}

TY - JOUR

T1 - GONADOTROPIN RELEASING HORMON TERHELESES TESZTRE KAPOTT HYPOPHYSEALIS VALASZ ERTEKELESE OLIGOZOOSPERMIA ESETEBEN

AU - Koloszar, S.

AU - Szöllősi, J.

PY - 1995

Y1 - 1995

N2 - Twenty-two infertile men with oligozoospermia were selected for gonadotrophin releasing hormone loading test. Prior to the test semen analyses, ultrasound examination of the testis and plasma FSH, LH, prolactin and testosterone determination were performed in ail cases. The basal values of FSH, LH and prolactin were (0.23-2.84 IU/l), (0.81-6.42 IU/l), (116-398 mU/l), respectively. During the test 100 mcg GnRH (Lutrelef®, Ferring) was given intravenously and blood samples were taken in every 15, 30, 60, 90, 120, 180 minutes after the injection. Plasma FSH, LH, prolactin and testosterone levels were measured by RIA method. In 11 case (1st group) hypophyseal response was reactive (increase in FSH 2-fold and LH 4-fold or more). The average increase in FSH in 6 cases (1.5-fold: 2nd group) and in LH 5 cases (2.5-3.0-fold: 3rd group) was less than in normal conditions. Our data demonstrate that in case of reactive GnRH loading test the pulsatile GnRH (1st group), pure FSH i.m. (2nd group) and human menopausal gonadotrophin i.m. or human chorionic gonadotrophin i.m. (3rd group) administration is the applicable hormone treatment strategy in case of oligozoospermia.

AB - Twenty-two infertile men with oligozoospermia were selected for gonadotrophin releasing hormone loading test. Prior to the test semen analyses, ultrasound examination of the testis and plasma FSH, LH, prolactin and testosterone determination were performed in ail cases. The basal values of FSH, LH and prolactin were (0.23-2.84 IU/l), (0.81-6.42 IU/l), (116-398 mU/l), respectively. During the test 100 mcg GnRH (Lutrelef®, Ferring) was given intravenously and blood samples were taken in every 15, 30, 60, 90, 120, 180 minutes after the injection. Plasma FSH, LH, prolactin and testosterone levels were measured by RIA method. In 11 case (1st group) hypophyseal response was reactive (increase in FSH 2-fold and LH 4-fold or more). The average increase in FSH in 6 cases (1.5-fold: 2nd group) and in LH 5 cases (2.5-3.0-fold: 3rd group) was less than in normal conditions. Our data demonstrate that in case of reactive GnRH loading test the pulsatile GnRH (1st group), pure FSH i.m. (2nd group) and human menopausal gonadotrophin i.m. or human chorionic gonadotrophin i.m. (3rd group) administration is the applicable hormone treatment strategy in case of oligozoospermia.

KW - Gonadotrophin releasing hormone

KW - Loading test

KW - Oligozoospermia

UR - http://www.scopus.com/inward/record.url?scp=0028810182&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028810182&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0028810182

VL - 58

SP - 361

EP - 363

JO - Magyar Noorvosok Lapja

JF - Magyar Noorvosok Lapja

SN - 0025-021X

IS - 5

ER -