Validation of videodensitometric myocardial perfusion assessment: Research Article

Ferenc T. Nagy, Attila Nemes, Tamás Szucsborus, Tamás Ungi, András Katona, Viktor Sasi, Zsolt Zimmermann, Anita Kalapos, T. Forster, Imre Ungi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Invasive methods for assessment of coronary microcirculatory function are time- and instrumentation-consuming tools. Recently, novel computer-assisted videodensitometric methods have been demonstrated to provide quantitative information on myocardial (re)perfusion. The aim of the present prospective study was to evaluate the accuracy of videodensitometry-derived perfusion parameters in patients with stable angina undergoing elective coronary angiography. Methods: The study comprised 13 patients with borderline epicardial coronary artery stenosis (40-70%). Coronary flow reserve and index of microcirculatory resistance were measured by using an intracoronary pressure and temperature sensor-tipped guidewire. A videodensitometric quantitative parameter of myocardial perfusion was calculated by the ratio of maximal density (Gmax) and the time to reach maximum density (Tmax) of the time-density curves in regions of interest on conventional coronary angiograms. Myocardium perfusion reserve was calculated as a ratio of hyperemic and baseline Gmax/Tmax. Results: At hyperemia a significant increase in Gmax/Tmax could be observed (p max/Tmax and hyperemic index of microcirculatory resistance (r =-0.72, p =0.0058). Conclusions: Videodensitometric Gmax/Tmax assessment seems to be a promising method to assess the myocardial microcirculatory state.

Original languageEnglish
Pages (from-to)600-607
Number of pages8
JournalCentral European Journal of Medicine
Volume8
Issue number5
DOIs
Publication statusPublished - Oct 2013

Fingerprint

Perfusion
Research
Stable Angina
Coronary Stenosis
Hyperemia
Coronary Angiography
Myocardium
Angiography
Prospective Studies
Pressure
Temperature

Keywords

  • Coronary flow reserve
  • Fractional flow reserve
  • Index of microcirculatory resistance
  • Videodensitometry

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nagy, F. T., Nemes, A., Szucsborus, T., Ungi, T., Katona, A., Sasi, V., ... Ungi, I. (2013). Validation of videodensitometric myocardial perfusion assessment: Research Article. Central European Journal of Medicine, 8(5), 600-607. https://doi.org/10.2478/s11536-013-0168-3

Validation of videodensitometric myocardial perfusion assessment : Research Article. / Nagy, Ferenc T.; Nemes, Attila; Szucsborus, Tamás; Ungi, Tamás; Katona, András; Sasi, Viktor; Zimmermann, Zsolt; Kalapos, Anita; Forster, T.; Ungi, Imre.

In: Central European Journal of Medicine, Vol. 8, No. 5, 10.2013, p. 600-607.

Research output: Contribution to journalArticle

Nagy, FT, Nemes, A, Szucsborus, T, Ungi, T, Katona, A, Sasi, V, Zimmermann, Z, Kalapos, A, Forster, T & Ungi, I 2013, 'Validation of videodensitometric myocardial perfusion assessment: Research Article', Central European Journal of Medicine, vol. 8, no. 5, pp. 600-607. https://doi.org/10.2478/s11536-013-0168-3
Nagy, Ferenc T. ; Nemes, Attila ; Szucsborus, Tamás ; Ungi, Tamás ; Katona, András ; Sasi, Viktor ; Zimmermann, Zsolt ; Kalapos, Anita ; Forster, T. ; Ungi, Imre. / Validation of videodensitometric myocardial perfusion assessment : Research Article. In: Central European Journal of Medicine. 2013 ; Vol. 8, No. 5. pp. 600-607.
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