A Thoenes-fele citomorfologiai 'Mainz klasszifikacio' alkalmazasa vesesejtes rakok hisztologiai osztalyozasakor

Translated title of the contribution: Use of Thoenes cytomorphological ('Mainz') classification for human renal cell cancer (RCC) histological subtyping

I. Buzogany, T. Magyarlaki, K. Villanyi, F. Sukosd

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Most of the renal malignant tumors are histogenetically derived from the cortical tubules or collecting ducts of the kidney parenchyma. A wide variety of histological classifications is still used in the practice. This motivated us to study the clinicopathological renal cell carcinoma classification published recently in 1990 by Thoenes. In our study histological parameters like cytomorphological tumor type (clear, chromophil, chromophob, 'Bellini duct', oncocytoma, pleomorphic, mixed), tumor growth pattern (compact, tubulopapillary, cystic, mixed) and tumor grade were compared with the clinical stage of 137 renal cell cancer patients. The results showed that most of our patients were histologically characterized to have 'clear' (94/137) 68% or 'chromophil (13/137) 9,4%, i.e. renal cell cancers of proximal tubule origin (107/137) 78%. Significantly higher number of early clinical stages (R I-II) were found in these cancers of proximal tubular type (p <0,0270). No significant correlation (p <0,8455) between tumor grade and clinical stage was found. The prognostic meaning of these findings needs to be further analysed. In conclusion the 'Mainz' classification is histogenetically logical, easy to reproduce and suggested for general use in the clinicopathological practice.

Original languageHungarian
Pages (from-to)324-331
Number of pages8
JournalMagyar Urologia
Volume9
Issue number4
Publication statusPublished - 1997

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Renal Cell Carcinoma
Neoplasms
Collecting Kidney Tubules
Oxyphilic Adenoma
Kidney
Growth

ASJC Scopus subject areas

  • Urology

Cite this

A Thoenes-fele citomorfologiai 'Mainz klasszifikacio' alkalmazasa vesesejtes rakok hisztologiai osztalyozasakor. / Buzogany, I.; Magyarlaki, T.; Villanyi, K.; Sukosd, F.

In: Magyar Urologia, Vol. 9, No. 4, 1997, p. 324-331.

Research output: Contribution to journalArticle

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