Use of porous graphitized carbon column for determining taxol in Taxus baccata

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Abstract

Porous graphitized carbon columns have been used for the separation and quantitative determination of the anticancer drug taxol in the bark and foliage of Taxus baccata. Successful separations were achieved using water:dioxane 54:46 v/v eluent. Peak purity tests and the spectra of taxol peaks taken at different retention times indicated that the taxol peak is not entirely homogeneous and probably contains other taxoteres coeluted with the main compound.

Original languageEnglish
Pages (from-to)740-742
Number of pages3
JournalChromatographia
Volume39
Issue number11-12
DOIs
Publication statusPublished - Dec 1 1994

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Keywords

  • Column liquid chromatography
  • Porous graphitized carbon
  • Taxol
  • Taxus baccata

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry

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