Hidroxi-propil-metil-cellulóz (methocel) és karboxi-metil-cellulóz (CMC) alapú münyálak alkalmazása a xerostomia tüneti kezelésében.

Translated title of the contribution: Use of hydroxy-propyl-methyl cellulose (methocel) and carboxy-methyl cellulose containing artificial saliva in the symptomatic treatment of xerostomia

G. Nagy, E. Olveti, M. Zeher, S. Márton, G. Keszthelyi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Salivary gland hypofunction is a common sequela of Sjögren's syndrome and irradiation treatment of tumors in head and neck region. The aim of the present study was to evaluate the therapeutic effect of a recently developed hydroxy-propyl-methyl-cellulose (HPMC) containing artificial saliva and to compare it with that of the carboxy-methyl-cellulose (CMC) based saliva substitute. The therapeutic effects of both preparations were assessed by means of self-administered questionnaires which had to be completed before and after the use of each type of artificial saliva after one week treatment. We found significant improvement in symptoms of nocturnal discomfort and difficulty in speech, and results were better in case of HPMC based artificial saliva. The retention time in oral cavity and the frequency of daily administration also were better in case of HPMC containing preparation. It is concluded that the use of HPMC containing artificial saliva can be recommended in the treatment of salivary hypofunction.

Original languageHungarian
Pages (from-to)299-304
Number of pages6
JournalFogorvosi szemle
Volume88
Issue number9
Publication statusPublished - Sep 1995

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Artificial Saliva
Xerostomia
Methylcellulose
Therapeutic Uses
Therapeutics
Salivary Glands
Saliva
Mouth
Neck
Head
Neoplasms

Cite this

Hidroxi-propil-metil-cellulóz (methocel) és karboxi-metil-cellulóz (CMC) alapú münyálak alkalmazása a xerostomia tüneti kezelésében. / Nagy, G.; Olveti, E.; Zeher, M.; Márton, S.; Keszthelyi, G.

In: Fogorvosi szemle, Vol. 88, No. 9, 09.1995, p. 299-304.

Research output: Contribution to journalArticle

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