Use of distance-based topological indices in modeling antihypertensive activity: Case of 2-aryl-imino-imidazolidines

Vijay K. Agrawal, Sneha Karmarkar, Padmakar V. Khadikar, Shachi Shrivastava, Istavan Lukovits

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8 Citations (Scopus)


This paper describes topological modeling of amihypertensive activity of 2-aryl-imino-imidazolidines. A large pool of distance-based topological indices consisting of W, B, χ J, Sz, and log RB is initially used for this purpose. An excellent model is obtained in multi-parametric regression containing χ and logRB along with two indicator parameters.

Original languageEnglish
Pages (from-to)1426-1435
Number of pages10
JournalIndian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry
Issue number6
Publication statusPublished - Jun 1 2003


ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

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