Use of Bioplant HTR Synthetic bone to eliminate major jawbone defects

Long-term human histological examinations

G. Szabo, Z. Suba, J. Barabás

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

This article describes the long-term follow-up of Bioplant HTR Synthetic bone (HTR: hard tissue replacement) in the human organism, as revealed by clinical, radiological and histological examinations and observations over a period of 5 years. Twenty-nine patients with lesions, 9 keratocysts, 16 radicular cysts, 3 traumatic cysts and 1 odontome were followed continuously during this period. All patients selected for follow-up had two criteria in common: the initial intervention had been performed at least 5 years previously; and the largest diameter of the bone defect was at least 2 cm. In all cases, when large bone defects were filled with HTR, the cavity was eventually filled with newly formed and remodelled bone. The process of ossification was relatively slow. In these cases, complete bony regeneration took up to 5 years. Ossification did not continue in the soft parts around the bone cavity. The histological pictures confirmed complete bone healing over the time.

Original languageEnglish
Pages (from-to)63-68
Number of pages6
JournalJournal of Cranio-Maxillofacial Surgery
Volume25
Issue number2
Publication statusPublished - 1997

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Bone and Bones
Osteogenesis
Tooth Abnormalities
Radicular Cyst
Odontogenic Cysts
HTR bioplant
Cysts
Regeneration

ASJC Scopus subject areas

  • Dentistry(all)
  • Otorhinolaryngology
  • Surgery

Cite this

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abstract = "This article describes the long-term follow-up of Bioplant HTR Synthetic bone (HTR: hard tissue replacement) in the human organism, as revealed by clinical, radiological and histological examinations and observations over a period of 5 years. Twenty-nine patients with lesions, 9 keratocysts, 16 radicular cysts, 3 traumatic cysts and 1 odontome were followed continuously during this period. All patients selected for follow-up had two criteria in common: the initial intervention had been performed at least 5 years previously; and the largest diameter of the bone defect was at least 2 cm. In all cases, when large bone defects were filled with HTR, the cavity was eventually filled with newly formed and remodelled bone. The process of ossification was relatively slow. In these cases, complete bony regeneration took up to 5 years. Ossification did not continue in the soft parts around the bone cavity. The histological pictures confirmed complete bone healing over the time.",
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