Urinary tract infection presenting with conjugated bilirubinaemia and the plasma amino acid pattern in young infants

G. Soltész, J. Mestyan, T. Dizseri

Research output: Contribution to journalArticle

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Abstract

Fasting blood glucose and plasma free amino acid levels were determined in 16 infants (average postnatal age, 44±6 days) suffering from urinary tract infection associated with jaundice and cholestasis. There were no significant differences in the fasting blood glucose values of the control and jaundiced babies. The concentration of two glucogenic amino acids: alanine and lysine, decreased significantly and phenylalanine, citrulline and cystine levels were elevated, suggesting an impairment of the metabolism of these amino acids in the liver. A close positive correlation was found between bilirubin, SGPT and phenylalanine concentration. After 2 to 4 wk. of antibiotic treatment the urine became sterile, bilirubinemia disappeared and the amino acid levels returned to normal.

Original languageEnglish
Pages (from-to)211-219
Number of pages9
JournalActa Paediatrica Academiae Scientiarum Hungaricae
Volume19
Issue number3
Publication statusPublished - 1978

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Hyperbilirubinemia
Urinary Tract Infections
Amino Acids
Jaundice
Phenylalanine
Blood Glucose
Fasting
Citrulline
Cystine
Cholestasis
Alanine Transaminase
Bilirubin
Alanine
Lysine
Urine
Anti-Bacterial Agents
Liver
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Urinary tract infection presenting with conjugated bilirubinaemia and the plasma amino acid pattern in young infants. / Soltész, G.; Mestyan, J.; Dizseri, T.

In: Acta Paediatrica Academiae Scientiarum Hungaricae, Vol. 19, No. 3, 1978, p. 211-219.

Research output: Contribution to journalArticle

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