Urinary steroids at time of surgery in postmenopausal women with breast cancer

Susan Juricskay, I. Szabó, Károly Kett

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Urinary steroid metabolites were measured by capillary gas chromatography in 22 postmenopausal women with operable breast cancer on day before the tumour excision and in 20 hospitalised control who were before an operation from other cause than cancer. Serum dehydroepiandrosterone-sulphat (DHEAS) and testosterone (T) level were measured by radioimmunassay in the same groups and same time. There was no significant difference in the level of urinary androgen metabolites. Pregnanediol level was significantly lower (P <0.05) in cancer patients. In the 5 patients with positive axillary nodes the tetrahydrocortisol and α-cortolone levels were significantly (P <0.05) higher than in node negative ones. There was no significant differences in the serum DHEAS and T levels. These results indicate that metabolic changes are existing in postmenopausal patients which may be a cause or a consequence of the disease.

Original languageEnglish
Pages (from-to)83-89
Number of pages7
JournalBreast Cancer Research and Treatment
Volume44
Issue number1
Publication statusPublished - 1997

Fingerprint

Dehydroepiandrosterone
Steroids
Breast Neoplasms
Tetrahydrocortisol
Pregnanediol
Neoplasms
Serum
Gas Chromatography
Androgens
Testosterone
cortolone

Keywords

  • Breast cancer
  • Capillary gas chromatography
  • Postmenopausal women
  • Urine steroids

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Urinary steroids at time of surgery in postmenopausal women with breast cancer. / Juricskay, Susan; Szabó, I.; Kett, Károly.

In: Breast Cancer Research and Treatment, Vol. 44, No. 1, 1997, p. 83-89.

Research output: Contribution to journalArticle

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