A kalciumürítés vizsgálata. (A vizelet kalcium/kreatinin hányadosának magyarországi normálértékei). Multicentrikus tanulmány.

Translated title of the contribution: Urinary calcium excretion. (Normal values for urinary calcium/creatinine ratio in Hungary). Multicenter study

P. Lakatos, I. Takács, B. Büki, J. Németh, C. Horváth

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Metabolic bone disorders have attracted increasing attention in Hungary due to their significant impact on public health care. Measuring urinary calcium excretion is the first step in the biochemical assessment of bone metabolism. Fasting urinary calcium corrected by creatinine excretion is widely used all over the world. The aim of the present study was to establish standard methods and normal values for the calcium/creatinine ratio in Hungary. Twenty-four centers specializing in metabolic bone diseases participated in the study. Urine standards were sent out to these centers for calcium and creatine determinations. Based on the collected data, methods were corrected in order to achieve similar results for the standards. In the second phase of the study, the normal values for calcium/creatinine ratio were determined in SI units based on the data from 1846 healthy subjects (age 20-80 yrs) including 944 females and 902 males. The normal value for females was 0.438 +/- 0.391 (means +/- SD), and 0.395 +/- 0.352 for males, respectively (p <0.03). The ratio increased with age in both sexes. The highest values were observed between 60-64 years in women and 70-74 years in men, respectively. After this peak, the calcium/creatinine ratio decreased. The values before and after 45 years of age were significantly different both in women (0.37 +/- 0.36, vs. 0.52 +/- 0.41, p <0.001; and men (0.32 +/- 0.23, vs. 0.47 +/- 0.45, p <0.001). The use of this distinction is recommended in the everyday practice.

Original languageHungarian
Pages (from-to)1405-1409
Number of pages5
JournalOrvosi Hetilap
Volume138
Issue number22
Publication statusPublished - Jun 1 1997

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Hungary
Multicenter Studies
Creatinine
Reference Values
Calcium
International System of Units
Bone and Bones
Creatine
Metabolic Bone Diseases
Fasting
Healthy Volunteers
Public Health
Urine
Delivery of Health Care

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A kalciumürítés vizsgálata. (A vizelet kalcium/kreatinin hányadosának magyarországi normálértékei). Multicentrikus tanulmány. / Lakatos, P.; Takács, I.; Büki, B.; Németh, J.; Horváth, C.

In: Orvosi Hetilap, Vol. 138, No. 22, 01.06.1997, p. 1405-1409.

Research output: Contribution to journalArticle

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