Uptake of heparin by cells

G. Csaba, Eszter Kapa

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

IN a previous communication1 we showed that the epithelial cells and lymphocytes of the thymus gland are capable of being converted into mast cells under conditions of tissue proliferation. With the view of confirming the correctness of this finding, we added partially decomposed heparin in cultures of thymus, spleen and lymph-node tissues and found that the heparinoid substance was taken up considerably by the thymus and by the other two tissues to a lesser extent. The heparinoid matter is then synthesized into complete metachromatic substance in the cells2. Tissues obtained from new-born to 1-month-old rats were used in those experiments. We have now attempted to ascertain whether there exists such a difference between the various tissues also in respect of heparin which has not been decomposed and to observe the behaviour of the different tissues in respect to their readiness to take up heparin in the successive phases of ontogenesis.

Original languageEnglish
Pages (from-to)711-713
Number of pages3
JournalNature
Volume187
Issue number4738
DOIs
Publication statusPublished - 1960

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Heparin
Heparinoids
Thymus Gland
Mast Cells
Spleen
Lymph Nodes
Epithelial Cells
Lymphocytes

ASJC Scopus subject areas

  • General

Cite this

Uptake of heparin by cells. / Csaba, G.; Kapa, Eszter.

In: Nature, Vol. 187, No. 4738, 1960, p. 711-713.

Research output: Contribution to journalArticle

Csaba, G & Kapa, E 1960, 'Uptake of heparin by cells', Nature, vol. 187, no. 4738, pp. 711-713. https://doi.org/10.1038/187711a0
Csaba, G. ; Kapa, Eszter. / Uptake of heparin by cells. In: Nature. 1960 ; Vol. 187, No. 4738. pp. 711-713.
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