Uptake of beta-hydroxybutyrate, acetoacetate and glucose by the forearm of the newborn infant.

B. Melegh, J. Kerner, M. Vincellér, G. Kispál

Research output: Contribution to journalArticle

Abstract

Forearm muscle metabolism was studied in twelve appropriate for gestational age premature infants suffering from respiratory distress. Arterial blood was obtained by puncture of the radial artery as clinically indicated for measuring oxygen tension, and venous blood samples were taken from the same arm's deep brachial vein. This arrangement allowed to study the arterial-deep venous differences of beta-hydroxybutyrate, acetoacetate and glucose in simultaneously taken blood samples. Net muscular uptakes of beta-hydroxybutyrate and glucose were observed, however, in four studies a virtual net production of acetoacetate was found. The arterial-deep venous concentration differences of both ketone bodies correlated positively with their arterial concentration within the 20 to 120 nanomol/ml range. Such a correlation was not observed in glucose utilization. It is concluded that forearm muscles in the neonate take up ketone bodies and this is in part concentration regulated.

Original languageEnglish
Pages (from-to)323-327
Number of pages5
JournalActa Paediatrica Hungarica
Volume27
Issue number4
Publication statusPublished - 1986

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3-Hydroxybutyric Acid
Forearm
Ketone Bodies
Newborn Infant
Glucose
Arm
Muscles
Radial Artery
Punctures
Premature Infants
Gestational Age
Veins
Oxygen
acetoacetic acid

ASJC Scopus subject areas

  • Medicine(all)

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Uptake of beta-hydroxybutyrate, acetoacetate and glucose by the forearm of the newborn infant. / Melegh, B.; Kerner, J.; Vincellér, M.; Kispál, G.

In: Acta Paediatrica Hungarica, Vol. 27, No. 4, 1986, p. 323-327.

Research output: Contribution to journalArticle

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