Local Multipoint Distribution Service (LMDS) is an emerging technology among broadband point-to-multipoint (PMP) wireless networks. The most critical point in designing LMDS networks is interference. Dominant access methods are FDMA and TDMA in LMDS, whereas CDMA received less attention. In this paper our aim is to demonstrate the feasibility of applying CDMA in LMDS networks with exploiting the results of research activities in CDMA interference suppression (e.g. multiuser detection). Uplink direction is the bottleneck of cellular PMP networks in terms of interference. Therefore, we analyzed uplink interference in CDMA-based LMDS networks. Frequency-sectorized TDMA uplink interference scenarios were compared to those of CDMA using single user detector (matched filter) and multiuser detection algorithms i.e. parallel interference cancellation (PIC) and successive interference cancellation (SIC). Uplink investigations of an LMDS sector by carrier to interference ratio (C/I) maps and BER vs. SNR simulations are presented.