A D-fruktoz szokatlan viselkedese dimetilon(IV)2+ kation jelenleteben: Az alkoholos hidroxilcsoport femion altal indukalt deprotonalodasa vizes kozegben, alacsony pH-n

Translated title of the contribution: Unusual coordination behavior of D-fructose towards dimethyltin(IV)2+: Metal-promoted deprotonation of alcoholic OH groups in aqueous solutions of low pH

Nagy László, Buzás Norbert, Barátné Jankovics Hajnalka, Gajda Tamás, Kuzmann Erno, Vértes Attila, Burger Kálmán

Research output: Contribution to journalArticle

Abstract

To study the effect of the conformation of sugar hydroxy groups on metal complexation processes, complex formation of eight saccharides (D-fructose, L-sorbose, L-arabinose, D-arabinose, D-glucose, D-sorbitol, 2-deoxy-D-glucose and D-saccharose) with dimethyltin(IV)2+ cations was investigated in aqueous solution by potentiometric equilibrium measurements, 13C NMR, polarimetric and Mossbauer spectroscopic methods. The experimental results proved that deprotonation of D-fructose and L-sorbose is caused by the coordination of dimethyltin(IV)2+ in the unusual low pH interval 4-6 in contrast to the other saccharides deprotonated in analogous way at pH > 8. Increasing the pH of the solution resulted in the formation of further complexes. Stability and composition of the species was determined by potentiometric studies. 13C NMR measurements led to the assignment of the sugar OH groups participating in the processes. Mossbauer investigations in the quick-frozen solutions permitted the determination of the stereochemistry of tin(IV) in the complexes.

Translated title of the contributionUnusual coordination behavior of D-fructose towards dimethyltin(IV)2+: Metal-promoted deprotonation of alcoholic OH groups in aqueous solutions of low pH
Original languageHungarian
Pages (from-to)9-19
Number of pages11
JournalActa pharmaceutica Hungarica
Volume69
Issue number1
Publication statusPublished - Jan 1999

ASJC Scopus subject areas

  • Pharmaceutical Science

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