Unexpected change of the sense of the enantioselective hydrogenation of ethyl pyruvate catalyzed by a Pt-alumina-cinchona alkaloid system

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

In the enantioselective hydrogenation of ethyl pyruvate (EtPy) over β-isocinchonine (β-ICN) modified Pt-alumina catalysts, the major enantiomer was (R)-ethyl lactate ((R)-EtLt (ee 50%)) in toluene, while in AcOH (S)-EtLt (ee 60%) was formed; the (R) configuration is opposite to what is expected from the absolute configuration of the cinchonine backbone.

Original languageEnglish
Pages (from-to)1130-1131
Number of pages2
JournalChemical Communications
Volume2
Issue number10
DOIs
Publication statusPublished - Jan 1 2002

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Unexpected change of the sense of the enantioselective hydrogenation of ethyl pyruvate catalyzed by a Pt-alumina-cinchona alkaloid system'. Together they form a unique fingerprint.

  • Cite this