Uncommon lymphadenopathies of immunopathogenesis can be misinterpreted as malignant diseases

László Váróczy, Árpád Illés, Lajos Gergely, Zsófia Simon, Ali Bassam, László Krenács

Research output: Contribution to journalArticle

1 Citation (Scopus)


Lymphadenomegaly is a common sign of benign and malignant disorders. In our practice, only every fifth patient is found to have primary or secondary nodal malignancy. Benign disorders, including banal infections and other non-neoplastic conditions, however, cause most of the cases. Among these, there are some rare entities, resulting in persistent lymphadenopathy that may cause differential diagnostic problems in the daily practice. We report here three patients, having Rosai-Dorfman disease, multicentric Castleman's disease and Kikuchi's lymphadenitis, who exemplify such cases. Our purpose with this presentation is to emphasise importance of vigorous co-operation between clinicians and pathologists. In general, it is imperative to prefer specialised haematopathological laboratories that may facilitate proper diagnosis.

Original languageEnglish
Pages (from-to)753-757
Number of pages5
JournalRheumatology International
Issue number8
Publication statusPublished - Jun 1 2007


  • Castleman's disease
  • Kikuchi's lymphadenitis
  • Lymphadenomegaly
  • Malignant lymphoma
  • Rosai-Dorfman disease

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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