Ultrastructure of the thymus and the neuromuscular junction in patients with myasthenia

S. Szekamova, G. Répássy, K. Lapis

Research output: Contribution to journalArticle

Abstract

Ultrastructural changes in 35 neuromuscular junctions taken from myasthenic patients (in 2 cases: hyperplasia of the thymus, in 1 case: epithelial thymoma was present) treated with anticholinesterase during 1-2 years, appeared to be similar to those observed in non-myasthenic patients with lymphoid thymoma (getting no treatment with anticholinesterase). Number of the secretory granules in the epithelial cells of the thymus was in accordance with the severity of the disease. It can be assumed that in the disturbance of the neuro-muscular transmission of the stimuli the activation of the epithelial cells may play a part.

Original languageEnglish
Pages (from-to)107-116
Number of pages10
JournalMorphologiai es igazsagugyi orvosi szemle
Volume18
Issue number2
Publication statusPublished - 1978

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Thymoma
Neuromuscular Junction
Cholinesterase Inhibitors
Thymus Gland
Thymus Hyperplasia
Epithelial Cells
Muscle Weakness
Secretory Vesicles
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

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Ultrastructure of the thymus and the neuromuscular junction in patients with myasthenia. / Szekamova, S.; Répássy, G.; Lapis, K.

In: Morphologiai es igazsagugyi orvosi szemle, Vol. 18, No. 2, 1978, p. 107-116.

Research output: Contribution to journalArticle

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