A hörgónyálkahártya ultrastrukturális vizsgálata ciliaris dyskinesia gyanúja esetén.

Translated title of the contribution: Ultrastructural study of bronchial mucosa in suspicion of ciliary dyskinesia

L. Tiszlavicz, Z. Rázga, G. Baktai, E. Péterffy, T. Márialigeti, K. Gyurkovits, A. Szabó

Research output: Contribution to journalArticle

Abstract

In the ciliary dyskinesia (immotile cilia syndrome) shows the partial or total lacking of cilia's elements. The ciliary dyskinesia may be developed congenital or acquired. The authors report on the experience with 72 biopsies from bronchial mucosa of 68 children, submitted with the question of immotile cilia syndrome. On micrographs (M: 64,000x) of the specimens processed by routine electron microscopical method the number of outer and inner dynein arm, A and B peripheral tubules, central tubules and central sheet were determined to normal 9 + 2 structure. 50-100 ciliaris per case were examined. Total or partial lacking of dynein and non-dynein elements were expressed for the total number of ciliaris compartments. Considering any earlier quantitative examination with this expression there was ease to characterised the quantitative behaviour of the components of ciliaris. Seven Kartagener's syndrome cases was the positive control for determined the quantitative differences between the primer and secondary ciliary changes. In the primary ciliary defects where the situs inversus were presented the total lacking of outer or/and inner dynein arms, where the situs inversus were not presented only the total lacking of inner dynein arms could be found. In secondary ciliary defects the partial lacking of the dynein arms and tubular components were presented. The used method is suitable to characterise the primary or secondary ciliary defects of bronchial mucosa.

Original languageHungarian
Pages (from-to)1349-1353
Number of pages5
JournalOrvosi hetilap
Volume141
Issue number24
Publication statusPublished - Jun 11 2000

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tiszlavicz, L., Rázga, Z., Baktai, G., Péterffy, E., Márialigeti, T., Gyurkovits, K., & Szabó, A. (2000). A hörgónyálkahártya ultrastrukturális vizsgálata ciliaris dyskinesia gyanúja esetén. Orvosi hetilap, 141(24), 1349-1353.