Ultrastructural changes in the nerve elements in Crohn's disease.

V. Szabó, E. Fehér

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Electron microscopic investigations were carried out to study the nerve elements in the wall of the small intestine in Crohn's disease, comparing it with the control. In the ileum of Crohn's disease only a few synapses were found. The number of nerve terminals were decreased, as well as that of the vesicle population in the remaining nerve terminals. Some of the nerve processes were observed in degeneration. The number of the lysosomes in the nerve cell bodies increased. Inflammatory cells as lymphocytes, plasma cells, mast cells were noted in the tola submucosa and in the mucous membrane, their number was also increased. It is suggested that the immunological effector cells and their products could be responsible for changing the neuronal elements.

Original languageEnglish
Pages (from-to)25-32
Number of pages8
JournalActa Chirurgica Hungarica
Volume32
Issue number1
Publication statusPublished - 1991

Fingerprint

Crohn Disease
Lysosomes
Plasma Cells
Ileum
Mast Cells
Synapses
Small Intestine
Mucous Membrane
Lymphocytes
Electrons
Neurons
Population
Cell Body

ASJC Scopus subject areas

  • Surgery

Cite this

Ultrastructural changes in the nerve elements in Crohn's disease. / Szabó, V.; Fehér, E.

In: Acta Chirurgica Hungarica, Vol. 32, No. 1, 1991, p. 25-32.

Research output: Contribution to journalArticle

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