Malformations of the abdominal and thoracic walls are amongst the most important malformations. In addition to their high incidence rate, they carry a special importance since they are frequently complicated with/linked to other malformations. The aim of our investigation was to check the accuracy and possible mistakes of prenatal diagnoses in case of thoracic/abdominal wall defects. In our study, we processed detailed data of 69 pregnancies, terminated at our department on medical grounds due to abdominal and thoracic wall malformations. Data procession was based on the computerized database of the department. In case of gastroschisis, omphalocele and diaphragmatic hernia the mean maternal ages were 25±5.63, 28±4.73 and 27±5.37 years, respectively. Positive history was significantly lower (<0.05) in gastroschisis as compared to omphalocele and diaphragmatic hernia. In case of gastroschisis and omphalocele, a practically similar girl dominance was seen, while in case of diaphragmatic hernia a male dominance was found. Among the complications associated with the aforementioned malformations, those effecting the cardiovascular system and, consequently, the respiratory system were especially common. As far as the diagnostic efficacy of sonography is considered, it was found that, based on the foetopathological investigations, the hit rate accuracy for omphalocele and diaphragmatic hernia was equally high being approximately 75%, while in case of gastroschisis, autopsy confirmed the sonographic findings in only 55% of the patients. In this latter malformation, in approximately 38% (11) of the cases, the post mortem findings yielded a completely different diagnosis. Upon comparing the cases of gastroschisis, prenatal sonographic diagnosis turned out to be much more accurate in cases of diaphragmatic hernias and omphaloceles. Since omphalocele is relatively often diagnosed for gastroschisis and because omphalocele and chromosomal anomalies are often associated, it makes a point to perform intrauterine karyotyping in the cases diagnosed as gastroschisis and appearing to have a better prognosis. Since gastroschisis is relatively often complicated with various cardiovascular malformations, the necessity of performing echocardiography also emerges.
|Translated title of the contribution||Ultrasonographic diagnosis of abdominal and thoracic wall malformations in foetopathological investigations|
|Number of pages||7|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - Jan 1 2008|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology