Two-year outcomes in patients admitted with non-ST elevation acute coronary syndrome: Results of the OASIS registry 1 and 2

Dorairaj Prabhakaran, Salim Yusuf, Shamir Mehta, Janice Pogue, Alvaro Avezum, Andrzej Budaj, Leszek Cerumzynski, Marcus Flather, Keith Fox, David Hunt, Liu Lisheng, M. Keltai, Alexander Parkhomenko, Prem Pais, Srinath Reddy, Mikhail Ruda, Tan Hiquing, Zhu Jun

Research output: Contribution to journalArticle

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Abstract

Background: Acute coronary syndrome continues to have significant long-term morbidity and mortality. This study sought to compare baseline characteristics, practice patterns and clinical outcomes for patients with non-ST elevation acute coronary syndrome from a broad range of low-, middle- and high-income countries. Methods and Results: We compared the data from a prospective registry of patients with non-ST elevation acute coronary syndrome involving 4615 patients from 65 centers in 8 low and middle income countries (OASIS registry 2) with those obtained from 7987 patients from 95 centers in 6 middle and high income countries (OASIS registry 1). Patients in the OASIS registry 2 were younger, were more often males and smokers, presented later to the hospital after symptom onset and had a lower prevalence of diabetes at admission [with the exception of India, which had the highest age-adjusted prevalence (39.1%)]. There were marked variations in the angiography and intervention rates during the hospital stay, but the uses of proven pharmacological therapies were comparable. The two-year mortality rates adjusted for baseline covariates ranged from 6.9% to 15%. Patients from China had the lowest two-year mortality rate (6.9%) and patients from India had the highest rate (15%). Combining the two registries, the covariate-adjusted rate of death or myocardial infarction did not differ across countries with in-hospital angiographic rates of ≥50% (17.1%), 25-49% (16.7%) or

Original languageEnglish
Pages (from-to)217-225
Number of pages9
JournalIndian Heart Journal
Volume57
Issue number3
Publication statusPublished - May 2005

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Acute Coronary Syndrome
Registries
Mortality
India
Physicians' Practice Patterns
poly(divinyl-co-N-vinylpyrrolidinone)
China
Length of Stay
Angiography
Myocardial Infarction
Pharmacology
Morbidity

Keywords

  • Acute coronary syndrome
  • Coronary artery disease
  • Unstable angina

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Prabhakaran, D., Yusuf, S., Mehta, S., Pogue, J., Avezum, A., Budaj, A., ... Jun, Z. (2005). Two-year outcomes in patients admitted with non-ST elevation acute coronary syndrome: Results of the OASIS registry 1 and 2. Indian Heart Journal, 57(3), 217-225.

Two-year outcomes in patients admitted with non-ST elevation acute coronary syndrome : Results of the OASIS registry 1 and 2. / Prabhakaran, Dorairaj; Yusuf, Salim; Mehta, Shamir; Pogue, Janice; Avezum, Alvaro; Budaj, Andrzej; Cerumzynski, Leszek; Flather, Marcus; Fox, Keith; Hunt, David; Lisheng, Liu; Keltai, M.; Parkhomenko, Alexander; Pais, Prem; Reddy, Srinath; Ruda, Mikhail; Hiquing, Tan; Jun, Zhu.

In: Indian Heart Journal, Vol. 57, No. 3, 05.2005, p. 217-225.

Research output: Contribution to journalArticle

Prabhakaran, D, Yusuf, S, Mehta, S, Pogue, J, Avezum, A, Budaj, A, Cerumzynski, L, Flather, M, Fox, K, Hunt, D, Lisheng, L, Keltai, M, Parkhomenko, A, Pais, P, Reddy, S, Ruda, M, Hiquing, T & Jun, Z 2005, 'Two-year outcomes in patients admitted with non-ST elevation acute coronary syndrome: Results of the OASIS registry 1 and 2', Indian Heart Journal, vol. 57, no. 3, pp. 217-225.
Prabhakaran, Dorairaj ; Yusuf, Salim ; Mehta, Shamir ; Pogue, Janice ; Avezum, Alvaro ; Budaj, Andrzej ; Cerumzynski, Leszek ; Flather, Marcus ; Fox, Keith ; Hunt, David ; Lisheng, Liu ; Keltai, M. ; Parkhomenko, Alexander ; Pais, Prem ; Reddy, Srinath ; Ruda, Mikhail ; Hiquing, Tan ; Jun, Zhu. / Two-year outcomes in patients admitted with non-ST elevation acute coronary syndrome : Results of the OASIS registry 1 and 2. In: Indian Heart Journal. 2005 ; Vol. 57, No. 3. pp. 217-225.
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AU - Pogue, Janice

AU - Avezum, Alvaro

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AU - Cerumzynski, Leszek

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AU - Hunt, David

AU - Lisheng, Liu

AU - Keltai, M.

AU - Parkhomenko, Alexander

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