Two types of neuron are found within the PPT, a small percentage of which project to both the LM-SG and SC

Kaeko Hoshino, Attila Nagy, Gabriella Eördegh, György Benedek, Masao Norita

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The pedunculopontine tegmental nucleus (PPT) projects its cholinergic fibers to both the lateralis medialis-suprageniculate nucleus (LM-Sg) and the superior colliculus (SC). For the purpose of verification of whether a single neuron in the PPT projects to both the LM-Sg and the SC, we injected dextran tetramethylrhodamine (DR) into the LM-Sg and dextran fluorescein (DF) into the ipsilateral SC. The DR-positive neurons labeled retrogradely in the PPT are small (mean: 27.13±1.22 μm) and distributed in the rostral two-thirds of this nucleus, whereas the DF-positive neurons are small (mean: 27.54±1.16 μm) or medium-sized (mean: 40.18±1.43 μm), and are located throughout the PPT Thirty-five percent of all labeled neurons are double-labeled and small. The present study indicates that the PPT projection to the LM-Sg in part involves neurons bifurcating to the SC.

Original languageEnglish
Pages (from-to)421-426
Number of pages6
JournalExperimental brain research
Volume155
Issue number4
DOIs
Publication statusPublished - Apr 1 2004

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Keywords

  • Bifurcating
  • Fluorescent double labeling
  • Visual thalamus
  • Visuomotor

ASJC Scopus subject areas

  • Neuroscience(all)

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