Tumor necrosis faktor-alpha

az elhízás-inzulinrezisztencia-nem inzulindependens diabetes mellitus kapcsolat lehetséges patogenetikai faktora?

Translated title of the contribution: Tumor necrosis factor-alpha; a possible pathogenic factor in obesity in insulin resistant and non-insulin-dependent diabetes mellitus?

G. Winkler, F. Salamon, K. Simon, K. Cseh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The role of tumor necrosis factor (TNF)-alpha in the development of insulin resistance has repeatedly been emphasized in the past few years. The present paper summarizes the data (including the authors' observations as well) focusing on the potential role of TNF-alpha in the pathogenesis of obesity and non-insulin-dependent diabetes mellitus: alteration of insulin receptor function, lipid metabolism, expression of sulphonylurea receptors, all of them suggested to be related to the TNF-alpha. The potential clinical relevances are shortly reviewed.

Original languageHungarian
Pages (from-to)1627-1632
Number of pages6
JournalOrvosi Hetilap
Volume139
Issue number27
Publication statusPublished - Jul 5 1998

Fingerprint

Type 2 Diabetes Mellitus
Tumor Necrosis Factor-alpha
Obesity
Insulin
Sulfonylurea Receptors
Insulin Receptor
Lipid Metabolism
Insulin Resistance

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tumor necrosis faktor-alpha : az elhízás-inzulinrezisztencia-nem inzulindependens diabetes mellitus kapcsolat lehetséges patogenetikai faktora? / Winkler, G.; Salamon, F.; Simon, K.; Cseh, K.

In: Orvosi Hetilap, Vol. 139, No. 27, 05.07.1998, p. 1627-1632.

Research output: Contribution to journalArticle

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