Tumor Growth Control by TP-LPV-LMI Based Controller

Gyorgy Eigner, Daniel Andras Drexler, L. Kovács

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The advantages of using advanced control techniques related to physiological applications are unquestionable as it was proven in many cases in the recent times. Although, there are several challenges that practitioners need to face. For example, the lack of precise information about the internal state of the patients, i.e. the inter-and intra-patient variabilities which cause uncertainties that need to be tolerated by the applied controllers. In this study an alternative solution is presented for control of tumor growth. Uncertainties and nonlinearities are handled by the applied Linear Parameter Varying (LPV) methodology completed by Tensor Product (TP) model transformation. Linear Matrix Inequalities (LMI) based optimization are used for controller design. The lack of information about the internal state is solved by using Extended Kalman Filter (EKF) to estimate the non-measurable state variables. The developed control structure is able to enforce the controlled system to behave as a predefined reference system. We show that the control framework operates well and reaches the determined aims of the control.

Original languageEnglish
Title of host publicationProceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2564-2569
Number of pages6
ISBN (Electronic)9781538666500
DOIs
Publication statusPublished - Jan 16 2019
Event2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018 - Miyazaki, Japan
Duration: Oct 7 2018Oct 10 2018

Publication series

NameProceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018

Conference

Conference2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018
CountryJapan
CityMiyazaki
Period10/7/1810/10/18

Fingerprint

Linear matrix inequalities
Uncertainty
Tensors
Tumors
Controllers
Growth
Neoplasms
Extended Kalman filters
Linear matrix inequality
Growth control
Tumor
Controller

Keywords

  • Linear Matrix Inequality
  • Linear Parameter Varying
  • Parallel Distribution Control
  • Tensor Model transformation
  • tumor control

ASJC Scopus subject areas

  • Information Systems
  • Information Systems and Management
  • Health Informatics
  • Artificial Intelligence
  • Computer Networks and Communications
  • Human-Computer Interaction

Cite this

Eigner, G., Drexler, D. A., & Kovács, L. (2019). Tumor Growth Control by TP-LPV-LMI Based Controller. In Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018 (pp. 2564-2569). [8616435] (Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SMC.2018.00439

Tumor Growth Control by TP-LPV-LMI Based Controller. / Eigner, Gyorgy; Drexler, Daniel Andras; Kovács, L.

Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. Institute of Electrical and Electronics Engineers Inc., 2019. p. 2564-2569 8616435 (Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Eigner, G, Drexler, DA & Kovács, L 2019, Tumor Growth Control by TP-LPV-LMI Based Controller. in Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018., 8616435, Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018, Institute of Electrical and Electronics Engineers Inc., pp. 2564-2569, 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018, Miyazaki, Japan, 10/7/18. https://doi.org/10.1109/SMC.2018.00439
Eigner G, Drexler DA, Kovács L. Tumor Growth Control by TP-LPV-LMI Based Controller. In Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. Institute of Electrical and Electronics Engineers Inc. 2019. p. 2564-2569. 8616435. (Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018). https://doi.org/10.1109/SMC.2018.00439
Eigner, Gyorgy ; Drexler, Daniel Andras ; Kovács, L. / Tumor Growth Control by TP-LPV-LMI Based Controller. Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 2564-2569 (Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018).
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