Trends in the epidemiology of human G1P[8] rotaviruses: A Hungarian study

K. Bányai, Jon R. Gentsch, Vito Martella, Àgnes Bogdán, V. Havasi, P. Kisfali, A. Szabó, Ilona Mihály, Péter Molnár, B. Melegh, György Szücs

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Epidemiological trends of the globally most common rotavirus genotype, G1P[8], were investigated in Hungary during a 16-year period by sequencing and phylogenetic analysis of the surface antigens. Antigen shift among epidemiologically major G1P[8] strains was observed in 6 seasons, as indicated by changes in the sublineages of the G1 VP7 and the P[8] VP4 genes. The temporal clustering of some rotavirus VP4 and VP7 gene sublineages and the periodic emergence and/or resurgence of previously unrecognized rotavirus sublineages in the study population suggest a dynamic nature for these common strains. Recently established international strain surveillance networks may help to identify and track the spread of epidemiologically important rotavirus strains across countries and continents.

Original languageEnglish
JournalJournal of Infectious Diseases
Volume200
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Nov 2009

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Rotavirus
Epidemiology
Hungary
Surface Antigens
Genes
Cluster Analysis
Genotype
Antigens
Population

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology and Allergy

Cite this

Trends in the epidemiology of human G1P[8] rotaviruses : A Hungarian study. / Bányai, K.; Gentsch, Jon R.; Martella, Vito; Bogdán, Àgnes; Havasi, V.; Kisfali, P.; Szabó, A.; Mihály, Ilona; Molnár, Péter; Melegh, B.; Szücs, György.

In: Journal of Infectious Diseases, Vol. 200, No. SUPPL. 1, 11.2009.

Research output: Contribution to journalArticle

Bányai, K. ; Gentsch, Jon R. ; Martella, Vito ; Bogdán, Àgnes ; Havasi, V. ; Kisfali, P. ; Szabó, A. ; Mihály, Ilona ; Molnár, Péter ; Melegh, B. ; Szücs, György. / Trends in the epidemiology of human G1P[8] rotaviruses : A Hungarian study. In: Journal of Infectious Diseases. 2009 ; Vol. 200, No. SUPPL. 1.
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