Treatment with pantethine

Zoltán Horváth, L. Vécsei

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The current increase in cardiovascular and cerebrovascular morbidity is a growing burden for society. Consideration must therefore be given to compounds capable of slowing down these pathological processes without significant adverse effects. The natural vitamins pantetheine/pantothenic acid are major precursors of coenzyme A and acyl carrier protein, which are essential for fatty acid oxidation and participate in the metabolism of cholesterol and carbohydrates and in at least 70 other enzymatic processes. Following a number of theoretical considerations and clinical observations, various clinical studies have revealed that they possess significant beneficial effects. In particular, they demonstrate useful moderating effects on vascular pathological processes, lowering lipid levels, and inhibiting platelet functions and lipid peroxidation. Although they are natural, well-tolerated therapeutic agents, few controlled clinical trials have been conducted. The available data suggest the need for larger clinical trials and possible use of pantetheine/pantothenic acid as adjuvant therapy.

Original languageEnglish
Pages (from-to)21-28
Number of pages8
JournalJournal of Evidence-Based Complementary and Alternative Medicine
Volume16
Issue number2
Publication statusPublished - 2011

Fingerprint

Pantetheine
Pantothenic Acid
Pathologic Processes
Acyl Carrier Protein
Essential Fatty Acids
Controlled Clinical Trials
Carbohydrate Metabolism
Coenzyme A
Vitamins
Lipid Peroxidation
Blood Vessels
Blood Platelets
Cholesterol
Clinical Trials
Morbidity
Lipids
Therapeutics
pantethine

Keywords

  • Atherosclerosis
  • Coenzyme A
  • Cysteamine
  • Dyslipidemia
  • Lipids
  • Pantetheine
  • Pantethine
  • Pantothenic acid
  • PKAN
  • Platelets

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

Treatment with pantethine. / Horváth, Zoltán; Vécsei, L.

In: Journal of Evidence-Based Complementary and Alternative Medicine, Vol. 16, No. 2, 2011, p. 21-28.

Research output: Contribution to journalArticle

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